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List of works by Anne Eckert

A new link to mitochondrial impairment in tauopathies.

scientific article

Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction

scientific article

Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects

scientific article published on 15 October 2020

Acute stress induced modifications of calcium signaling in learned helpless rats

scientific article published in July 2000

Advanced Mitochondrial Respiration Assay for Evaluation of Mitochondrial Dysfunction in Alzheimer's Disease

scientific article published in January 2016

Age-related alteration of activity and gene expression of endothelial nitric oxide synthase in different parts of the brain in rats

scientific article published in November 2004

Age-related changes of apoptotic cell death in human lymphocytes

scientific article published on 01 September 2000

Age-related impairment of human T lymphocytes' activation: specific differences between CD4(+) and CD8(+) subsets

scientific article published in February 2002

Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761).

scientific article

Aging enhances the calcium sensitivity of central neurons of the mouse as an adaptive response to reduced free intracellular calcium

scientific article

Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice

scientific article published on 15 November 2005

Allopregnanolone and its analog BR 297 rescue neuronal cells from oxidative stress-induced death through bioenergetic improvement.

scientific article

Alterations of intracellular calcium regulation during aging and Alzheimer's disease in nonneuronal cells

scientific article published on January 1994

Alzheimer's disease models and functional genomics-How many needles are there in the haystack?

scientific article

Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship

scientific article

Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.

scientific article published in April 2001

Alzheimer, mitochondria and gender

scientific article published on 29 April 2016

Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.

scientific article

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

scientific article

Amyloid-Beta interaction with mitochondria

scientific article

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

scientific article

Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells

scientific article published on 7 April 2009

Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity

scientific journal article

Apolipoprotein E epsilon 4 is associated with an increased vulnerability to cell death in Alzheimer's disease

scientific article published in June 2006

Apoptosis of CD4+ T and Natural Killer Cells in Alzheimer's Disease

scientific article published on 01 November 2006

BDNF in sleep, insomnia, and sleep deprivation

scientific article

BDNF: an indicator of insomnia?

scientific article published on 12 February 2013

Brain aging and neurodegeneration: from a mitochondrial point of view

scientific article published on 11 April 2017

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

scientific article published on 24 July 2020

Changes of intracellular calcium regulation in Alzheimer's disease and vascular dementia

scientific article

Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration

scientific article published on 25 November 2009

Convergence of amyloid-beta and tau pathologies on mitochondria in vivo

scientific article

Decreased beta-amyloid sensitivity in Alzheimer's disease

scientific article published in September 1993

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

scientific journal article

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

scientific article

Dissecting toxicity of tau and beta-amyloid

scientific article

Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects

scientific article published on 16 November 2019

Disturbances of the neuronal calcium homeostasis in the aging nervous system

scientific article published on January 1994

Diurnal pattern of serum BDNF before partial sleep deprivation in stress-related mood disorders – an association with therapy response in major depression

article published in 2012

Dose-dependent and sequence-sensitive effects of amyloid-beta peptide on neurosteroidogenesis in human neuroblastoma cells

scientific article

Down-regulation of free intracellular calcium in dissociated brain cells of aged mice and rats

scientific article published in January 1996

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

scientific article

Effects of Aerobic Exercise as Add-On Treatment for Inpatients With Moderate to Severe Depression on Depression Severity, Sleep, Cognition, Psychological Well-Being, and Biomarkers: Study Protocol, Description of Study Population, and Manipulation Ch

Effects of Alzheimer's amyloid-beta and tau protein on mitochondrial function -- role of glucose metabolism and insulin signalling

scientific article published on June 2007

Effects of EGb 761 Ginkgo biloba extract on mitochondrial function and oxidative stress.

scientific article

Elevated intracellular calcium levels after 5-HT2 receptor stimulation in platelets of patients with affective disorders

Elevated levels of fragmented DNA nucleosomes in native and activated lymphocytes indicate an enhanced sensitivity to apoptosis in sporadic Alzheimer's disease. Specific differences to vascular dementia

scientific article published in March 2001

Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation

scientific article published in April 2001

Enhanced ROS-generation in lymphocytes from Alzheimer's patients

scientific article published on November 2005

Enhanced apoptosis, oxidative stress and mitochondrial dysfunction in lymphocytes as potential biomarkers for Alzheimer's disease

scientific article published on January 2007

Enhanced vulnerability to apoptotic cell death in sporadic Alzheimerʼs disease

scientific article published on 01 August 1998

Fast BDNF serum level increase and diurnal BDNF oscillations are associated with therapeutic response after partial sleep deprivation

scientific article published on 16 September 2014

Free intracellular calcium in aging and Alzheimer's disease

scientific article published on June 1996

Free intracellular calcium in peripheral cells in Alzheimer's disease

scientific article published on May 1997

Gamma-hydroxybutyrate, acting through an anti-apoptotic mechanism, protects native and amyloid-precursor-protein-transfected neuroblastoma cells against oxidative stress-induced death.

scientific article published on 20 January 2014

Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease.

scientific article published on 19 July 2016

Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure

scientific article

Ginkgo biloba extract increases neurite outgrowth and activates the Akt/mTOR pathway

scientific article published on 02 December 2019

High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression

scientific article published on 23 February 2014

Hippocampal volume and functional connectivity changes during the female menstrual cycle

scientific article published on 6 June 2015

Honeybush Extracts (Cyclopia spp.) Rescue Mitochondrial Functions and Bioenergetics against Oxidative Injury

scientific article published on 07 August 2020

Impact of Aging: Sporadic, and Genetic Risk Factors on Vulnerability to Apoptosis in Alzheimer's Disease

scientific article published on 01 January 2003

Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain

scientific article published on 14 May 2004

Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice

scientific article published in February 2005

Impaired calcium regulation in subcortical vascular encephalopathy

scientific article published on July 1997

Improved Alertness Is Associated with Early Increase in Serum Brain-Derived Neurotrophic Factor and Antidepressant Treatment Outcome in Major Depression

scientific article published on 26 August 2015

Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders

scientific article published on 2 October 2014

Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy

scientific article published on 26 October 2007

Increased superior frontal gyrus activation during working memory processing in psychosis: Significant relation to cumulative antipsychotic medication and to negative symptoms

scientific article published on 18 April 2016

Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol

scientific article

Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio

scientific article published on 30 January 2012

Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death

scientific article published on 7 February 2007

Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity

scientific article published on 2 February 2011

Lymphocytes and neutrophils as peripheral models to study the effect of beta-amyloid on cellular calcium signalling in Alzheimer's disease

scientific article

Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered

scientific article published in January 1998

Mature brain-derived neurotrophic factor (BDNF) is the major player of total BDNF in serum regarding prediction of antidepressant treatment outcome

scientific article published on 24 September 2015

Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies

scientific article published on 13 October 2019

Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence.

scientific article published on 12 May 2019

Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity ⬇️

scientific article published on May 5, 2011

Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease

scientific article

Mitochondrial dysfunction induced by disease relevant AbetaPP and tau protein mutations.

scientific article published on July 2006

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

scientific article published on October 2003

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

scientific article

Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease--therapeutic aspects

scientific article published on 12 May 2010

Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease?

scientific article published on October 2007

Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease

scientific article published on 14 October 2015

Mitochondrial effects of Ginkgo biloba extract ⬇️

scientific article published on August 1, 2012

Modes of Aβ toxicity in Alzheimer's disease

scientific article

Modulation of neurosteroid production in human neuroblastoma cells by Alzheimer's disease key proteins

scientific article published in July 2006

Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

scientific article published on May 2003

Nitric oxide alters arachidonic acid turnover in brain cortex synaptoneurosomes.

scientific article published on 10 October 2005

Non-24-Hour Sleep-Wake Disorder Revisited - A Case Study

scientific article published on 29 February 2016

Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice

scientific article published on 16 August 2008

Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytes

scientific article published on 22 July 2012

Pilot study of the application of magnetic bead protein profiling to the study of biomarkers in addiction research

scientific article

Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease.

scientific article published in October 2006

Piracetam improves mitochondrial dysfunction following oxidative stress

scientific article

Plasma and serum brain-derived neurotrophic factor (BDNF) levels and their association with neurocognition in at-risk mental state, first episode psychosis and chronic schizophrenia patients

scientific article published on 25 June 2018

Platelet and lymphocyte free intracellular calcium in affective disorders

scientific article

Premature aging in mice with error-prone protein synthesis

scientific article published on 02 March 2022

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

scientific article published on 14 April 2005

ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain

scientific article

Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations

scientific article published in October 2000

Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease.

scientific article

Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death

scientific article

Region-specific downregulation of free intracellular calcium in the aged rat brain

scientific article

Repetitive enhancement of serum BDNF subsequent to continuation ECT

scientific article published on 11 September 2019

Role of Serum Brain Derived Neurotrophic Factor and Central N-Acetylaspartate for Clinical Response under Antidepressive Pharmacotherapy

scientific article published on February 2016

Role of hippocalcin in mediating Aβ toxicity

scientific article

Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons

scientific journal article

Selective regulation of neurosteroid biosynthesis in human neuroblastoma cells under hydrogen peroxide-induced oxidative stress condition

scientific article published on 3 December 2007

Serum factors in older individuals change cellular clock properties

scientific article

Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein

scientific article

Similar age-related changes of free intracellular calcium in lymphocytes and central neurons: effects of Alzheimer's disease

scientific article

Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex.

scientific article published on 23 August 2016

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

article

Stabilization of mitochondrial function by Ginkgo biloba extract (EGb 761).

scientific article published on 15 September 2007

Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin.

scientific article published on 17 July 2009

Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons

scientific article published on 24 April 2015

Systemic and cellular reflections on ageing and the circadian oscillator: a mini-review

scientific article published on 28 October 2010

Tau physiology and pathomechanisms in frontotemporal lobar degeneration

scientific article

The MT2 melatonin receptor subtype is present in human retina and decreases in Alzheimer's disease

scientific article

The amplifying effect of beta-amyloid on cellular calcium signalling is reduced in Alzheimer's disease

scientific article

The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion

scientific article published on 19 October 2006

The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis

scientific article published in October 2003

The interplay of stress and sleep impacts BDNF level

scientific article

The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptide

scientific article

The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts

scientific article

The role of BDNF, leptin, and catecholamines in reward learning in bulimia nervosa

scientific article

beta-Amyloid peptide decreases membrane fluidity

scientific article

beta-Amyloid protein amplifies calcium signalling in central neurons from the adult mouse

scientific article published in August 1993

β-Amyloid protein enhances the mitogen-induced calcium response in circulating human lymphocytes

scientific article published on 01 September 1993

β-amyloid amplifies PLC activity and Ca2+signalling in fully differentiated brain cells of adult mice

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