Search filters

List of works by Nicoletta Bianchi

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

article

A chromatographic procedure for fully automated isolation of DNA from human whole blood

scientific article published on 01 April 1994

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

scientific article published on 31 March 2012

A long non-coding RNA inside the type 2 transglutaminase gene tightly correlates with the expression of its transcriptional variants.

scientific article published on 8 January 2018

A validated cellular biobank for β-thalassemia

scientific article published on 02 September 2016

Accumulation of gamma-globin mRNA and induction of erythroid differentiation after treatment of human leukaemic K562 cells with tallimustine

scientific article

Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin

scientific article published in September 2003

Alteration of the expression of human estrogen receptor gene by distamycin

scientific article

Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.

scientific article published on January 2007

An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production

scientific article published on 29 August 2017

Analytic and Dynamic Secretory Profile of Patient-Derived Cytokine-Induced Killer Cells.

scientific article published on 9 August 2017

Arginine transport in human erythroid cells: discrimination of CAT1 and 4F2hc/y+LAT2 roles.

scientific article published on 28 June 2009

Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.

scientific article

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

scientific article published on 26 November 2017

Benzoyl nitrogen mustard derivatives of benzoheterocyclic analogues of netropsin: synthesis and biological activity

scientific article published on May 2003

Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

scientific article

Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.

scientific article published on 16 April 2009

Binding of distamycin and chromomycin to human immunodeficiency type 1 virus DNA: a non-radioactive automated footprinting study

scientific article published in July 1995

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

scientific article published in February 2004

Biosensor Technology and Surface Plasmon Resonance for Real-Time Detection of Genetically Modified Roundup Ready Soybean Gene Sequences

article

Biosensor technology and surface plasmon resonance for real-time detection of HIV-1 genomic sequences amplified by polymerase chain reaction.

scientific article published in November 1997

Biosensor technology for real-time detection of the cystic fibrosis W1282X mutation in CFTR.

scientific article published in January 2001

Capillary electrophoresis: detection of hybridization between synthetic oligonucleotides and HIV-1 genomic DNA amplified by polymerase-chain reaction.

scientific article published in May 1994

Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors

scientific article

Changes in Adipose Tissue Distribution and Association between Uric Acid and Bone Health during Menopause Transition ⬇️

scientific article published on 14 December 2019

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-kappaB binding sites.

scientific article published on December 2000

Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells

scientific article published on 4 May 2012

Design, Synthesis and Growth Inhibition Activity of Bis-Epoxyethyl Derivatives of Stallimycin Modified on the Amidino Moiety

Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid

scientific article published on 01 November 1998

Detection of the deltaF508 (F508del) mutation of the cystic fibrosis gene by surface plasmon resonance and biosensor technology.

scientific article published in January 1999

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

scientific article published on 2 September 2015

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

scientific article published on 9 July 2009

Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives.

scientific article published on August 2009

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.

scientific article

Effects on erythroid differentiation of platinum(II) complexes of synthetic bile acid derivatives

scientific article published on 18 May 2006

Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells

scientific article published in September 2004

Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin

scientific article

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

scientific article published on 03 December 2014

Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.

scientific article published on September 2010

Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell. Arg.) latex

scientific article published in March 2003

Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.

scientific article

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

scientific article published on June 2014

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

scientific article published on 11 December 2007

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

scientific article published on 4 May 2015

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

scientific article published on 24 December 2015

In vitro and in vivo binding of a CC-1065 analogue to human gene sequences: a polymerase-chain reaction study.

scientific article published in January 1997

In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa

scientific article

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

scientific article published on 25 September 2009

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

scientific article

Induction of erythroid differentiation of human K562 cells by 3-O-acyl-1,2-O-isopropylidene-D-glucofuranose derivatives

scientific article published on 01 November 1999

Induction of erythroid differentiation of human K562 cells by cisplatin analogs

scientific article

Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.

scientific article published on 13 October 2007

Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences

scientific article published on September 2008

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

scientific article

Involvement of miRNA in erythroid differentiation

scientific article published on February 2012

Involvement of non-coding RNAs and transcription factors in the induction of Transglutaminase isoforms by ATRA

scientific article published on 22 August 2019

MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells

scientific article published on 15 March 2016

MicroRNAs Modulate the Purinergic Signaling Network.

scientific article published on 9 September 2016

Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells

scientific article published on 8 May 2003

Modular usage of the HLA-DRA promoter in extra-hematopoietic and hematopoietic cell types of transgenic mice.

scientific article published on June 2005

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

scientific article

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

scientific article published on December 2001

Molecular methods for validation of the biological activity of peptide nucleic acids targeting microRNAs

scientific article published on January 2014

Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

scientific article

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

scientific article

Polymerase-chain reaction as a tool for investigations on sequence-selectivity of DNA-drugs interactions

scientific article published on 01 December 1994

Polymerase-chain reaction: analysis of DNA/DNA hybridization by capillary electrophoresis.

scientific article published on July 1993

Preparation and biological evaluation of some 1,2-O-isopropylidene-D-hexofuranose esters.

scientific article published on 17 January 2006

Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O-isopropylidene-D-mannofuranose.

scientific article published in February 2002

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

scientific article published on November 2009

Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells

scientific article published on 27 August 2008

Quantitation of Bt-176 maize genomic sequences by surface plasmon resonance-based biospecific interaction analysis of multiplex polymerase chain reaction (PCR).

scientific article published in July 2003

Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.

scientific article published on August 2004

Recent trends in the gene therapy of β-thalassemia

scientific article

Regulation of IL-8 gene expression in gliomas by microRNA miR-93.

scientific article published on 8 October 2015

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

scientific article

Sequencing of an RNA transcript of the human estrogen receptor gene: Evidence for a new transcriptional event

article

Sequencing of an upstream region of the human HLA-DRA gene containing X' and Y' boxes.

scientific article

Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.

scientific article

Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A.

scientific article published on July 2000

Synthesis and growth inhibition activity of alpha-bromoacrylic heterocyclic and benzoheterocyclic derivatives of distamycin A modified on the amidino moiety

scientific article

Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells

scientific article published on 10 May 2008

Synthesis of hybrid distamycin–cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents

scientific article published on 01 June 2000

Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1, 4]benzodiazepine and minor-groove-binding oligopyrrole carriers

scientific article

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

scientific article published on 16 August 2011

The DNA-binding drugs mithramycin and chromomycin are powerful inducers of erythroid differentiation of human K562 cells

scientific article published on February 1999

Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients

scientific article (publication date: 2012)

Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites

scientific article

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

scientific article published on 10 December 2010

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

scientific article published on 5 March 2014

Vav1 Selectively Down-Regulates Akt2 through miR-29b in Certain Breast Tumors with Triple Negative Phenotype

scientific article published in 2022

Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis.

scientific article

Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes.

scientific article published in December 2009

gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions

scientific article

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

scientific article published on December 2011

Paulina is supported by:

About Paulina

Help