List of works by Philip C. Trackman

A Polymorphism in the Lysyl Oxidase Propeptide Domain Accelerates Carcinogen-induced Cancer.

scientific article published on 22 March 2018

A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples

scientific article

A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer

scientific article published on 04 August 2009

A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia

scientific article

A procollagen C-proteinase inhibitor diminishes collagen and lysyl oxidase processing but not collagen cross-linking in osteoblastic cultures

scientific article published in April 2005

A role for advanced glycation end products in diminished bone healing in type 1 diabetes

scientific article published on June 2003

A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures

scientific article published on July 2004

Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes

scientific article published on 9 November 2006

Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways

scientific article published on 6 December 2004

Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor

scientific article published on 27 September 2006

Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.

scientific article published on 24 October 2006

An interesting perspective on a well-studied pathway: does type III TGF-Β receptor have therapeutic potential?

scientific article published on 22 February 2015

Apoptosis in gingival overgrowth tissues.

scientific article published on September 2007

Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts

scientific article published on 4 June 2003

Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide

scientific article

CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins

scientific article

Characterization of recombinant lysyl oxidase propeptide

scientific article published on April 2010

Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence [Erratum to document cited in CA112(25):230629x]

article

Collagen advanced glycation inhibits its Discoidin Domain Receptor 2 (DDR2)-mediated induction of lysyl oxidase in osteoblasts

scientific article published on 10 October 2013

Connective tissue growth factor in drug-induced gingival overgrowth

scientific article published in July 2001

Connective tissue metabolism and gingival overgrowth.

scientific article published on 4 June 2004

Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase

scientific article

Controlled release of fibroblast growth factor 2 stimulates bone healing in an animal model of diabetes mellitus.

scientific article published in September 2006

Corrigendum to "Orthotopic non-metastatic and metastatic oral cancer mouse models" [Oral Oncol. 51(5) (2015) 476-482]

scientific article published on 22 July 2017

Cytokine regulation of gingival fibroblast lysyl oxidase, collagen, and elastin

scientific article published in February 2002

Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide

scientific article published on 6 August 2015

Development of a peroxidase-coupled fluorometric assay for lysyl oxidase

article

Diabetes-induced fibrotic matrix inhibits intramembranous bone healing

scientific article published on 4 September 2014

Diverse biological functions of extracellular collagen processing enzymes

scientific article

Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis

scientific article

Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy

scientific article published on 16 September 2019

Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways

scientific article

Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures

scientific article

Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone

scientific article published on 06 January 2016

Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis.

scientific article published on September 2006

Epithelial to mesenchymal transition in gingival overgrowth

scientific article

Expression of metalloproteinases and their tissue inhibitors in inflamed gingival biopsies.

scientific article

Functional analysis of the promoter and first intron of the human lysyl oxidase gene

scientific article published in January 1996

Functional importance of lysyl oxidase family propeptide regions

scientific article published on 30 October 2017

Hereditary gingival fibromatosis associated with generalized aggressive periodontitis: a case report

scientific article published in May 2004

High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function

scientific article

Hypoxia-inducible factor 1-regulated lysyl oxidase is involved in Staphylococcus aureus abscess formation

scientific article published on 06 May 2013

Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus

scientific article published on 07 August 2019

Increased mRNAs for procollagens and key regulating enzymes in rat skeletal muscle following downhill running

article

Induction of lung lysyl oxidase activity and lysyl oxidase protein by exposure of rats to cadmium chloride: properties of the induced enzyme

scientific article published on 01 January 1991

Inflammation-associated lysyl oxidase protein expression in vivo, and modulation by FGF-2 plus IGF-1.

scientific article published in July 1998

Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide

scientific article published on 22 October 2013

Intracellular distribution of the lysyl oxidase propeptide in osteoblastic cells

scientific article published on 7 February 2007

Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress

scientific article published on 18 June 2019

Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer

scientific article published on 5 February 2016

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.

scientific article published on 21 May 2009

Lysyl oxidase and rrg messenger RNA.

scientific article published on August 1991

Lysyl oxidase is associated with increased thrombosis and platelet reactivity.

scientific article published on 11 January 2016

Lysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts

scientific article

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.

scientific article

Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation

scientific article published on 3 December 2007

Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis

scientific article published on December 2010

Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo

scientific article published on December 2015

Measurement of lysyl oxidase activity from small tissue samples and cell cultures.

scientific article published on 28 October 2017

Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB

scientific article published on 13 May 2019

Megakaryocyte polyploidy is inhibited by lysyl oxidase propeptide

scientific article published on 21 March 2013

Molecular and clinical aspects of drug-induced gingival overgrowth.

scientific article

Molecular events that contribute to lysyl oxidase enzyme activity and insoluble collagen accumulation in osteosarcoma cell clones

scientific article

Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes

scientific article published on 22 May 2018

Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016.

scientific article published in January 2018

Orthotopic non-metastatic and metastatic oral cancer mouse models

scientific article

Pre- and post-translational regulation of lysyl oxidase by transforming growth factor-beta 1 in osteoblastic MC3T3-E1 cells

scientific article published on December 1995

Prevention of phenytoin-induced gingival overgrowth by lovastatin in mice

scientific article published on 2 April 2015

Properties and Function of Lysyl Oxidase ⬇️

scientific article published on September 1, 1991

Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts

scientific article

Regulation of MMP-9 expression by the A2b adenosine receptor and its dependency on TNF-α signaling.

scientific article

Regulation of collagen deposition and lysyl oxidase by tumor necrosis factor-alpha in osteoblasts

scientific article published on 10 May 2004

Regulation of lysyl oxidase by basic fibroblast growth factor in osteoblastic MC3T3-E1 cells

scientific article published on March 1996

Report on the 7(th) international workshop on the CCN family of genes : October 16-19, 2013-Nice, France.

scientific article published on 20 February 2014

Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

scientific article published in July 2007

Requirement for active glycogen synthase kinase-3β in TGF-β1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts

scientific article published on 03 July 2013

Role of lysyl oxidase propeptide in secretion and enzyme activity

scientific article published on December 2010

Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice.

scientific article published on 5 November 2015

Stimulation of osteoblasts with Emdogain increases the expression of specific mineralization markers

scientific article published on 11 June 2008

Studies on Lysyl Oxidase of Bovine Ligamentum Nuchae and Bovine Aorta ⬇️

scientific article published on January 1, 1977

TGF-β1- and CCN2-Stimulated Sirius Red Assay for Collagen Accumulation in Cultured Cells.

scientific article published in January 2017

The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells

scientific article

The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells

scientific article

The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits β-catenin transcriptional activity in lung cancer cells

scientific article

The metabolism of 1-phospho-5-methylthioribose

scientific article published on December 1981

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

scientific article published on 23 July 2004

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

scientific article published on February 2007

Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase

scientific article published on 10 April 2007

Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN

scientific article published on 20 February 2008

UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells

scientific article

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