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List of works by Michele Galluccio

Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

scientific article published on 6 January 2018

Bacterial over-expression and purification of the 3'phosphoadenosine 5'phosphosulfate (PAPS) reductase domain of human FAD synthase: functional characterization and homology modeling

scientific article published on 11 December 2012

Bacterial production and reconstitution in proteoliposomes of Solanum lycopersicum CAT2: a transporter of basic amino acids and organic cations.

scientific article

Biosynthesis of flavin cofactors in man: implications in health and disease.

scientific article

Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark

scientific article published in 2021

Cloning, large scale over-expression in E. coli and purification of the components of the human LAT 1 (SLC7A5) amino acid transporter

scientific article published in August 2013

Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Effect of Cholesterol on the Organic Cation Transporter OCTN1 (SLC22A4)

scientific article published on 06 February 2020

Exploiting Cysteine Residues of SLC Membrane Transporters as Targets for Drugs

scientific article published on 28 June 2019

Functional and molecular effects of mercury compounds on the human OCTN1 cation transporter: C50 and C136 are the targets for potent inhibition

scientific article published on 8 December 2014

Functional reconstitution into liposomes and characterization of the carnitine transporter from rat liver microsomes

scientific article published on 30 January 2006

Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth.

scientific article published on 11 December 2017

Glutamine transport. From energy supply to sensing and beyond

scientific article published on 4 March 2016

Human FAD synthase (isoform 2): a component of the machinery that delivers FAD to apo-flavoproteins

scientific article published on 20 October 2011

Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain

scientific article published on 12 August 2015

Human OCTN2 (SLC22A5) is down-regulated in virus- and nonvirus-mediated cancer.

scientific article

Inactivation by Hg2+ and methylmercury of the glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: Prediction of the involvement of a CXXC motif by homology modelling

scientific article published on July 2010

Inflammation and Organic Cation Transporters Novel (OCTNs)

scientific article published in 2024

Insights into the transport side of the human SLC38A9 transceptor

scientific article published on 08 July 2019

Interaction of beta-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter

scientific article published on 21 March 2008

LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter.

scientific article published on 6 August 2015

Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris--functional and kinetic asymmetry revealed in proteoliposomes

scientific article published on 10 June 2013

Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring

scientific article published on 03 September 2020

Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health.

scientific article

Mitochondrial localization of human FAD synthetase isoform 1.

scientific article

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

scientific article published on 09 December 2019

Nesfatin-1 as a novel cardiac peptide: identification, functional characterization, and protection against ischemia/reperfusion injury.

scientific article

Novel insights into the transport mechanism of the human amino acid transporter LAT1 (SLC7A5). Probing critical residues for substrate translocation

scientific article published on 11 January 2017

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics

scientific article published on 07 December 2018

Over-expression in E. coli and purification of the human OCTN1 transport protein.

scientific article published on 28 June 2009

Over-expression in E. coli and purification of the human OCTN2 transport protein.

scientific article published in January 2012

Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase.

scientific article

Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase

scientific article

Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: the mouse carnitine transporter OCTN3.

scientific article published on 27 April 2012

Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs.

scientific article published on 11 July 2017

Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli.

scientific article

Reconstitution into liposomes of the glutamine/amino acid transporter from renal cell plasma membrane: functional characterization, kinetics and activation by nucleotides.

scientific article published in December 2004

Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system.

scientific article published on 30 April 2012

Regulatory Aspects of the Vacuolar CAT2 Arginine Transporter of : Role of Osmotic Pressure and Cations

scientific article published on 19 February 2019

Riboflavin transport and metabolism in humans

scientific article

Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency

scientific article

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

scientific article

Significance of redox-active cysteines in human FAD synthase isoform 2

scholarly article by Angelica Miccolis published in December 2014

Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamily ⬇️

scientific article published on June 1, 2013

Structure/function relationships of the human mitochondrial ornithine/citrulline carrier by Cys site-directed mutagenesis. Relevance to mercury toxicity

scientific article published on 16 August 2018

Studying interactions of drugs with cell membrane nutrient transporters: new frontiers of proteoliposome nanotechnology.

scientific article published on 15 June 2017

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health.

scientific article published on 22 June 2018

The glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: transport mechanism, regulation by ATP and characterization of the glutamine/glutamate antiport

scientific article published on 16 September 2006

The hidden side of the human FAD synthase 2

scientific article published on 24 July 2019

The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease.

scientific article

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