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List of works by Sebastian Grönke

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin

scientific article

A nutritional memory effect counteracts benefits of dietary restriction in old mice

scientific article published on 21 October 2019

A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.

scientific article published on 15 September 2017

A triple drug combination targeting components of the nutrient-sensing network maximizes longevity

scientific article published on 30 September 2019

Aβ43 is neurotoxic and primes aggregation of Aβ40 in vivo

scientific article published on 11 April 2015

Branched-Chain Amino Acids Have Equivalent Effects to Other Essential Amino Acids on Lifespan and Aging-Related Traits in Drosophila

scientific article published on 01 January 2020

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

scientific article published in May 2005

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

scientific article published on 07 August 2014

Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies

scientific article published on 10 November 2015

Control of fat storage by a Drosophila PAT domain protein.

scientific article published in April 2003

Curled encodes the Drosophila homolog of the vertebrate circadian deadenylase Nocturnin

scientific article published on 06 July 2009

Deletion of endogenous Tau proteins is not detrimental in Drosophila

scientific article published on 15 March 2016

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

scientific article published on 28 March 2017

Dual lipolytic control of body fat storage and mobilization in Drosophila

scientific article

Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain

scientific article published on 16 December 2019

Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

article

Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila

scientific article published on 09 August 2016

Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system

scientific article published in 2024

Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

scientific article

Insulin signalling regulates remating in female Drosophila

scientific article published on 25 August 2010

Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production

scientific article published on 13 November 2019

Loss of miR-210 leads to progressive retinal degeneration in

scientific article published on 22 January 2019

Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila

scientific article

MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals

scientific article

Molecular evolution and functional characterization of Drosophila insulin-like peptides

scientific article

Mutations of mitochondrial DNA are not major contributors to aging of fruit flies

article published in the Proceedings of the National Academy of Sciences of the United States of America

Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization ⬇️

scientific article published on April 14, 2012

Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity

scientific article published on 30 August 2017

Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster.

scientific article

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

scientific article published on 09 June 2021

Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD.

scientific article

The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster

scientific article

Tissue-specific modulation of gene expression in response to lowered insulin signalling in <i>Drosophila</i>

scientific article published on 21 April 2021

Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions

scientific article

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