List of works by Konrad Hochedlinger

A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.

scientific article published on March 2016

A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs

scientific article

A gutsy way to grow: intestinal stem cells as nutrient sensors.

scientific article published in October 2011

A high-efficiency system for the generation and study of human induced pluripotent stem cells

scientific article

A molecular roadmap of reprogramming somatic cells into iPS cells

scientific article published on December 2012

A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

scientific article

A reprogrammable mouse strain from gene-targeted embryonic stem cells

scientific article published on 13 December 2009

A variant CRISPR-Cas9 system adds versatility to genome engineering

scientific article published on 06 September 2013

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

scientific article

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

scientific article

An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition

scientific article published on 24 May 2018

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

scientific article published on 5 December 2008

Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells

scientific article

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization

scientific article

Balancing work and life: a conversation with Konrad Hochedlinger. Interview by Majlinda Lako and Susan Daher

scientific article published in May 2009

Cell reprogramming: Brain versus brawn

scientific article published on 8 June 2016

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

scientific article (publication date: August 2010)

Chromatin connections to pluripotency and cellular reprogramming

scientific article published on June 2011

Chromatin dynamics during cellular reprogramming

scientific article

Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy

scientific article

Corrigendum: Failure to replicate the STAP cell phenomenon

scientific article published on 16 December 2015

Corrigendum: Hallmarks of pluripotency

correction of a scholarly article

Cross-regulation of the Nanog and Cdx2 promoters

scientific article

DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells

scientific article

De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency

scientific article published on 02 May 2019

Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

scientific article published on 14 February 2008

Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis

scientific article published on April 2002

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

scientific article published on 09 August 2009

Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.

scientific article

Direct in vivo VH to JH rearrangement violating the 12/23 rule

scientific article

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

scientific article (publication date: 7 June 2007)

Disease-specific induced pluripotent stem cells

scientific article

Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity

scientific article published on 19 December 2013

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

scientific article published on September 2004

Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation

scientific article

Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium

scientific article

ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable

scientific article

Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes

scientific article published on 01 July 2007

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

scientific article

Efficient generation of iPS cells from skeletal muscle stem cells

scientific article (publication date: 2011)

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

scientific article published in January 2006

Embryonic stem cells: testing the germ-cell theory

scientific article published on 01 October 2011

Emerging roles of the histone chaperone CAF-1 in cellular plasticity

scientific article

Epigenetic reprogramming and induced pluripotency

scientific article published on February 2009

Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation

scientific article published on 6 July 2017

Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells

scientific article published on 02 August 2016

Failure to replicate the STAP cell phenomenon

scientific article published in September 2015

Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions

scientific article

From MYOD1 to iPS cells

scientific article published on 01 December 2010

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming

scientific article published on 9 May 2013

Guidelines and techniques for the generation of induced pluripotent stem cells

scientific article

Hallmarks of pluripotency

scientific article published on September 2015

Harnessing the potential of induced pluripotent stem cells for regenerative medicine

scientific article published in May 2011

Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency

scientific article published on December 2012

Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs

scientific article published on September 2014

Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination

scientific article published on February 2013

ISSCR 2013: back to Bean Town

scientific article published on 17 December 2013

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

scientific article

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.

scientific article published on 17 April 2011

Induced Pluripotency and Epigenetic Reprogramming

scientific article

Induced pluripotency: history, mechanisms, and applications

scientific article

Induced pluripotent stem cell generation using a single lentiviral stem cell cassette

scientific article published on March 2009

Induced pluripotent stem cells and reprogramming: seeing the science through the hype

scientific article published on 27 October 2009

Induced pluripotent stem cells generated without viral integration

scientific article (publication date: 7 November 2008)

Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo

scientific article published on 28 October 2019

Konrad Hochedlinger: the new kid of nuclear reprogramming

scientific article

Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea

scientific article

Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage

scientific article published on 22 June 2015

Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming

scientific article published on May 2016

Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency

scientific article

Modeling Rett Syndrome with Stem Cells ⬇️

scientific article published on November 12, 2010

Monoclonal mice generated by nuclear transfer from mature B and T donor cells

scientific article published on 10 February 2002

Nanog is dispensable for the generation of induced pluripotent stem cells

scientific article published on 23 January 2014

New advances in iPS cell research do not obviate the need for human embryonic stem cells

scientific article published on 01 October 2007

Novel Roles for SUMOylation in Cellular Plasticity

scientific article published on 26 October 2018

Nuclear Cloning, Epigenetic Reprogramming and Cellular Differentiation

Nuclear cloning of embryonal carcinoma cells

scholarly article

Nuclear cloning, epigenetic reprogramming and cellular differentiation.

scientific article

Nuclear cloning, stem cells, and genomic reprogramming

scientific article

Nuclear reprogramming and pluripotency

scientific article

Nuclear transplantation, embryonic stem cells and the potential for cell therapy

scientific article published on January 2004

Nuclear transplantation, embryonic stem cells, and the potential for cell therapy

scientific article

Nuclear transplantation: lessons from frogs and mice

scientific article

Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming

scientific article

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

scientific article published on 30 November 2017

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

scientific article published in January 2018

Oct4 expression is not required for mouse somatic stem cell self-renewal

scientific article

On the cloning of animals from terminally differentiated cells

scientific article published on 01 February 2007

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

scientific article published on 31 January 2019

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

scientific article published on 01 March 2019

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

scientific article published on 19 August 2015

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice

scientific article

Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes

scientific article

Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

scientific article published on December 2016

Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming

scientific article published on 12 July 2018

Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma

scientific article published on 19 June 2014

Rearranging the chromatin for pluripotency

scientific article published on 15 November 2013

Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells

scientific article published on 20 August 2018

Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system

scientific article published on 25 October 2012

Removing reprogramming roadblocks: Mbd3 depletion allows deterministic iPSC generation

scientific article published on 01 October 2013

Renewed proliferation in adult mouse cochlea and regeneration of hair cells

scientific article published on 04 December 2019

Reproductive biology: Stem cells bear eggs

scientific article published in November 2012

Reprogramming of a melanoma genome by nuclear transplantation

scientific article published on August 2004

Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression

scientific article

Reprogramming of pancreatic beta cells into induced pluripotent stem cells

scientific article

Reprogramming to recover youthful epigenetic information and restore vision

scientific article published on 02 December 2020

Reprogramming: identifying the mechanisms that safeguard cell identity

scientific article published on 02 December 2019

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

scientific article published on 31 July 2019

Small molecules facilitate rapid and synchronous iPSC generation

scientific article

Sox2 Suppresses Gastric Tumorigenesis in Mice

scientific article published on 3 August 2016

Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

scientific article published on September 2009

Sox2 marks epithelial competence to generate teeth in mammals and reptiles

scientific article published on 5 March 2013

Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice

scientific article

Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors

scientific article published on 19 July 2012

Stem cells assessed

scientific article published on 8 June 2012

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell ⬇️

scientific article published on October 18, 2010

TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes

scientific article

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

scientific article

Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc

scientific article

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis

scientific article published on 03 October 2019

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming

scientific journal article

The histone chaperone CAF-1 safeguards somatic cell identity

scientific article

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

scientific article published on 27 April 2015

The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development

scientific journal article

The sox family of transcription factors: versatile regulators of stem and progenitor cell fate

scientific article published on January 2013

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

scientific article published on 01 December 2018

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

scientific article published on 13 September 2018

When fibroblasts MET iPSCs

scientific article published on 17 June 2010

Without a trace? PiggyBac-ing toward pluripotency

scientific article published in May 2009

X chromosome choice occurs independently of asynchronous replication timing

scientific article

Your inner healers

scientific article published on 01 May 2010

gPS navigates germ cells to pluripotency

scientific article published on July 2009

iPS cells under attack

scientific article published in Nature

α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells

scientific article published on 27 July 2016

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