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List of works by Jeff Keelan

15-Deoxy-Delta(12,14)-prostaglandin J(2), a ligand for peroxisome proliferator-activated receptor-gamma, induces apoptosis in JEG3 choriocarcinoma cells

scientific article published on 01 September 1999

15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.

scientific article published on December 2001

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

scientific article published on October 2003

A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome.

scientific article published on 4 May 2018

A New, Potent, and Placenta-Permeable Macrolide Antibiotic, Solithromycin, for the Prevention and Treatment of Bacterial Infections in Pregnancy

scientific article published in 2016

A Specific Bacterial DNA Signature in the Vagina of Australian Women in Mid-Pregnancy Predicts High Risk of Spontaneous Preterm Birth (The Predict1000 Study)

scientific article published on 27 August 2020

A radioimmunoassay for plasma dehydroepiandrosterone sulphate incorporating placental steroid sulphatase as a hydrolysing reagent

scientific article published on 01 September 1986

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

scientific article published in December 2005

ABCA1 and placental cholesterol efflux

scientific article published on 24 June 2011

Active transport across the human placenta: impact on drug efficacy and toxicity

scientific article published on February 2006

Activin A exerts both pro- and anti-inflammatory effects on human term gestational tissues

scientific article published on 01 January 2000

Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity.

scientific article published on 13 January 2015

Altered placental lactogen and leptin expression in placentomes from bovine nuclear transfer pregnancies

scientific article published on 11 August 2004

Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

scientific article published on 20 August 2012

Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

scientific article published in Scientific Reports

Antioxidant defenses in the rat placenta in late gestation: increased labyrinthine expression of superoxide dismutases, glutathione peroxidase 3, and uncoupling protein 2

scientific journal article

Applying Precision Public Health to Prevent Preterm Birth.

scientific article published on 04 April 2017

Author Correction: Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

scientific article published on 15 April 2020

Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism

scientific article published on 27 November 2007

Ceramide biosynthesis and metabolism in trophoblast syncytialization.

scientific article

Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

scientific article

Characterization of the amnion-derived AV3 cell line for use as a model for investigation of prostaglandin-cytokine interactions in human amnion

scientific article

Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

scientific article published on 15 February 2019

Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture

scientific article published on 01 December 1994

Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

scientific article published on 24 March 2020

Comparison of Meconium DNA Extraction Methods for Use in Microbiome Studies.

scientific article published on 20 February 2018

Concentrations of activin A, inhibin A and follistatin in human amnion, choriodecidual and placental tissues at term and preterm

scientific article published on 01 October 1999

Cord blood androgen measurements: the importance of assay validation

scientific article published on 27 April 2017

Corticotropin-releasing hormone, corticotropin-releasing hormone–binding protein, and activin A in maternal serum: Prediction of preterm delivery and response to glucocorticoids in women with symptoms of preterm labor

article

Critical paracrine interactions between TNF-alpha and IL-10 regulate lipopolysaccharide-stimulated human choriodecidual cytokine and prostaglandin E2 production.

scientific article

Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition

scientific article published on 01 December 1999

Cytokine-induced coordinate expression of enzymes of prostaglandin biosynthesis and metabolism: 15-hydroxyprostaglandin dehydrogenase.

scientific article published in January 2000

Cytokines of the placenta and extra-placental membranes: biosynthesis, secretion and roles in establishment of pregnancy in women.

scientific article

Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition.

scientific article

Cytokines, hypoxia, and preeclampsia

scientific article published in September 2005

Cytosolic phospholipase A(2)and 15-hydroxyprostaglandin dehydrogenase mRNA expression in murine uterine and gestational tissues during late pregnancy

scientific article published on 01 April 2001

Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

scientific article published on 23 February 2015

Development of a model for functional studies of ABCG2 (breast cancer resistance protein) efflux employing a standard BeWo clone (B24).

scientific article

Does leptin exhibit cytokine-like properties in tissues of pregnancy?

scientific article published on May 2000

Drug transfer and metabolism by the human placenta.

scientific article published on January 2004

Drugs to block cytokine signaling for the prevention and treatment of inflammation-induced preterm birth

scientific article

Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort

scientific article published on 24 June 2016

Editorial: Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

scientific article published on 30 June 2016

Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

scientific article published on 3 February 2014

Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

scientific article

Effects of interleukin-4 on the expression and activity of prostaglandin endoperoxide H synthase-2 in amnion-derived WISH cells

scientific article published on December 1998

Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors.

scientific article

Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

scientific article

Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

scientific article published on 5 November 2014

Efficacy and specificity of non-steroidal anti-inflammatory drugs for the inhibition of cytokine-stimulated prostaglandin E(2) secretion by amnion-derived WISH cells.

scientific article published on May 2002

Enhanced Expression of Intercellular Adhesion Molecule-1 (ICAM-1) in Amnion with Term and Preterm Labour

scientific article published on 01 January 2000

Epithelial cell-derived neutrophil-activating peptide-78 is present in fetal membranes and amniotic fluid at increased concentrations with intra-amniotic infection and preterm delivery

scientific article published on 17 September 2003

Expression of TGF-beta1, TGF-beta2, TGF-beta3 and the receptors TGF-betaRI and TGF-betaRII in placentomes of artificially inseminated and nuclear transfer derived bovine pregnancies.

scientific article published on 13 June 2005

Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua

scientific article published on 01 September 2002

Expression of intercellular adhesion molecule-1 (ICAM-1) in choriodecidua with labour and delivery at term and preterm

scientific article published on 01 January 1999

Expression of interleukin-1beta mRNA in murine uterine and gestational tissues: relationship with gestational age

scientific article published on 01 December 2001

Expression of prostaglandin H synthase-1 and -2 in murine intrauterine and gestational tissues from mid pregnancy until term

scientific article published on 01 August 2001

Expression, localisation and activity of ATP binding cassette (ABC) family of drug transporters in human amnion membranes

scientific article published on 07 May 2007

Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual caps

scientific article published on 01 February 2001

Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta.

scientific article

High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

scientific article published on 11 December 2013

Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation.

scientific article

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid

scientific article published on August 2004

Hypoxia attenuates PGE(2)but increases prostacyclin and thromboxane production in human term villous trophoblast

scientific article published in July 2001

Hypoxia inhibits activin A production by term villous trophoblast in vitro

scientific article published in November 2002

IFPA Meeting 2009 workshops report

scientific article published on 12 January 2010

IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.

scientific article published on 6 January 2016

Identification and removal of contaminating microbial DNA from PCR reagents: impact on low biomass microbiome analyses

scientific article published on 23 November 2018

Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor

scientific article (publication date: March 2002)

In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin

scientific article published on 19 June 2015

In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes

scientific article published on 29 October 2014

In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

scientific article published on 3 June 2015

Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors

scientific article published on 19 January 2007

Inflammation of the fetal ovine skin following in utero exposure to Ureaplasma parvum

scientific article published in November 2011

Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.

scientific article

Innate inflammatory responses of human decidual cells to periodontopathic bacteria

scientific article published on 01 May 2010

Insulin resistance is not due to persistently elevated serum tumor necrosis-alpha levels in small for gestational age, premature, or twin children

scientific article published in March 2004

Insulin-like growth factor-I and binding proteins 1, 2, and 3 in bovine nuclear transfer pregnancies.

scientific article published on 15 October 2003

Intercellular adhesion molecule-1 (ICAM-1) in cervicovaginal fluid of women presenting with preterm labor: predictive value for preterm delivery

scientific article published on 01 May 2000

Interleukin (IL)-6 and IL-8 production by human amnion: regulation by cytokines, growth factors, glucocorticoids, phorbol esters, and bacterial lipopolysaccharide

scientific article published on December 1997

Interleukin-4 differentially regulates prostaglandin production in amnion-derived WISH cells stimulated with pro-inflammatory cytokines and epidermal growth factor

scientific article published on April 1999

Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model.

scientific article published on 3 February 2015

Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

article

Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

scientific article published on 22 December 2017

Labor-associated changes in interleukin-10 production and its regulation by immunomodulators in human choriodecidua.

scientific article

Letter to the editor: "fatty acids and placental transport: insight or in vitro artifact?"

scientific article published on 01 December 2014

Macrophage inhibitory cytokine 1 in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes

scientific article published on 01 September 2003

Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model

scientific article

Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

scientific article published on 24 August 2017

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

scientific article published on 30 May 2013

Maternal dietary omega-3 fatty acid supplementation reduces placental oxidative stress and increases fetal and placental growth in the rat

scientific article published on 14 February 2013

Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy

scientific article published on 25 August 2014

Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection

scientific article published on 30 June 2014

Maternal serum activin A is not elevated before preeclampsia in women who are at high risk

scientific article published on March 2003

Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

scientific article published on 08 April 2011

Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation.

scientific article

Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development

scientific article

Metabolizing enzyme localization and activities in the first trimester human placenta: the effect of maternal and gestational age, smoking and alcohol consumption

scientific article published in October 2002

Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

scholarly article by Hui Yang published in December 2018

Nanomolar and micromolar effects of 15-deoxy-delta 12,14-prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of peroxisome proliferator-activated receptors gamma and delta and nuclear factor kappa B.

scientific article published on 8 April 2005

Nanoparticulate drug delivery in pregnancy: placental passage and fetal exposure

scientific article published on May 2011

Nanotoxicology: nanoparticles versus the placenta

scientific article published on 01 May 2011

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

scientific article

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

scientific article published on 03 January 2011

Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

scientific article published on 10 February 2015

Paradoxical proinflammatory actions of interleukin-10 in human amnion: potential roles in term and preterm labour

scientific article

Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

scientific article

Perinatal testosterone exposure and cerebral lateralisation in adult males: evidence for the callosal hypothesis.

scientific article published on 20 August 2014

Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth.

scientific article published on 14 January 2011

Placental ABC transporters, cellular toxicity and stress in pregnancy

scientific article published on 20 March 2013

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity

scientific article published on 4 June 2010

Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

scientific article published on 08 August 2019

Placental cytokines and preeclampsia

scientific article published on January 2007

Placental enzymes and transporters: new functions and genetic polymorphisms--a workshop report

scientific article published on 26 March 2007

Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

scientific article

Polymyxin B agonist capture therapy for intrauterine inflammation: proof-of-principle in a fetal ovine model

scientific article published on 12 November 2013

Preclinical evaluation of drugs to block inflammation-driven preterm birth

scientific article published on 7 November 2016

Predicting preterm delivery: comparison of cervicovaginal interleukin (IL)-1β, IL-6 and IL-8 with fetal fibronectin and cervical dilatation

scientific article published on 01 April 2001

Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood.

scientific article published in October 2015

Prevention of inflammatory activation of human gestational membranes in an ex vivo model using a pharmacological NF-kappaB inhibitor

scientific article published on 25 September 2009

Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement

scientific article published on 01 June 2017

Prostaglandin H synthase-2 and cytosolic phospholipase A2 in the hypoxic-ischemic brain: role in neuronal death or survival?

scientific article

Prostanoid stimulation of cytokine production in an amnion-derived cell line: evidence of a feed-forward mechanism with implications for term and preterm labor

scientific article

Randomised controlled trial of nebulised gentamicin in children with bronchiectasis

Re-analysis of the association between perinatal androgens and postnatal head circumference growth

scientific article published on 22 August 2014

Re-analysis of the association between perinatal androgens and pragmatic language ability

scientific article published in November 2014

Re: "Amniotic fluid from healthy term pregnancies does not harbor a detectable microbial community" (2018) 6:87, https://doi.org/10.1186/s40168-018-0475-7

scientific article published on 12 February 2019

Recent advances in the prevention of preterm birth

scientific article

Reducing preterm birth by a statewide multifaceted program: an implementation study.

scientific article published on 24 November 2016

Regulation of activin A, inhibin A, and follistatin production in human amnion and choriodecidual explants by inflammatory mediators

scientific article

Regulation of activin-A production by human amnion, decidua and placenta in vitro by pro-inflammatory cytokines

scientific article published in July 1998

Regulation of cytosolic phospholipase A2 expression by cytokines in human amnion cells

scientific article published on May 1999

Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs

scientific article

Regulation of trophoblast migration and survival by a novel neural regeneration peptide

scientific article published on 04 April 2010

Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study

scientific article published on 01 October 2018

Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy

scientific article published on 28 February 2014

Role of Wnt signalling in early pregnancy

scientific article published on 05 September 2014

Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women

scientific article published on 30 September 2014

Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies

scientific article published in February 2002

Serum concentrations of human chorionic gonadotrophin and immunoreactive inhibin in early pregnancy and recurrent miscarriage: a longitudinal study

article

Sex differences in umbilical cord serum levels of inhibin, testosterone, oestradiol, dehydroepiandrosterone sulphate, and sex hormone-binding globulin in human term neonates

scientific article published on 01 January 1994

Sex-specific associations between umbilical cord blood testosterone levels and language delay in early childhood

scientific article published on 26 January 2012

Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization.

scientific article

Strategies to prevent preterm birth

scientific article published on 19 November 2014

Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization

scientific article

Suppressors of cytokine signaling proteins in human preterm placental tissues

scientific article published on 01 August 2005

T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy

scientific article published on 17 March 2016

Targeting Toll-like receptor-4 to tackle preterm birth and fetal inflammatory injury

scientific article published on 14 April 2020

Testicular function in a birth cohort of young men.

scientific article published on 25 September 2015

The 15-deoxy-delta(12,14)-prostaglandin J(2)receptor, peroxisome proliferator activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells

scientific article

The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction.

scientific article published on 26 June 2007

The Maternal Serological Response to Intrauterine Ureaplasma sp. Infection and Prediction of Risk of Pre-Term Birth

scientific article

The Not-so-Sterile Womb: Evidence That the Human Fetus Is Exposed to Bacteria Prior to Birth.

scientific article

The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age.

scientific article

The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study

scientific article published on 01 December 2018

The association between perinatal testosterone concentration and early vocabulary development: A prospective cohort study ⬇️

scientific article published on November 13, 2012

The impact of antenatal Bisphenol A exposure on male reproductive function at 20-22 years of age.

scientific article published on 19 December 2017

The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone

scientific article published on 30 April 2013

The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study

scientific article published on 2 March 2014

The influence of prenatal exposure to phthalates on subsequent male growth and body composition in adolescence

scientific article published on 15 October 2020

The molecular mechanisms of term and preterm labor: recent progress and clinical implications

scientific article published on September 1997

The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study

scientific article published on 7 June 2015

The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy.

scientific article published on 14 June 2016

The relationship between oxytocin blood concentrations and antidepressants over pregnancy and the postpartum

scientific article published on 17 December 2020

The relationship between umbilical cord estrogens and perinatal characteristics

scientific article published on 17 March 2014

The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations.

scientific article

The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells

scientific article published on 31 January 2007

Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy

scientific article published on July 2015

Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

scientific article published on 30 January 2018

Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

scientific article published on 22 September 2014

Transport of lipids by ABC proteins: interactions and implications for cellular toxicity, viability and function

scientific article published on 06 May 2009

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), TRAIL receptors, and the soluble receptor osteoprotegerin in human gestational membranes and amniotic fluid during pregnancy and labor at term and preterm

scientific article published on 01 August 2003

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

scientific article (publication date: February 2002)

Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population

scientific article

Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study.

scientific article published on 31 January 2017

Umbilical cord blood testosterone and childhood internalizing and externalizing behavior: a prospective study.

scientific article published in April 2013

Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women

scientific article published on 18 October 2016

Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm.

scientific article published in April 2002

Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

scientific article published on 07 February 2020

Vaginal microbiota during pregnancy: Pathways of risk of preterm delivery in the absence of intrauterine infection?

scientific article published on 29 October 2015

Whole blood flow cytometric analysis of Ureaplasma-stimulated monocytes from pregnant women

scientific article published on 13 January 2015

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