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List of works by Malcolm D. Tingle

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

scientific article published on October 2003

A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide

scientific article published in June 2001

A systematic review of clozapine-induced myocarditis

scientific article published in May 2018

Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy

scientific article published on 15 April 2011

Adenosine amine congener as a cochlear rescue agent

scientific article published on 26 August 2014

Aerobic 2- and 4-nitroreduction of CB 1954 by human liver

scientific article published on 29 August 2005

An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

scientific article published in November 1991

An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

scientific article published on 01 November 1993

Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes

scientific article

Ascending single dose pharmacokinetics of cytisine in healthy adult smokers

scientific article published on 11 December 2018

Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes.

scientific article published in February 1997

COMPARATIVE PROTEIN BINDING, STABILITY AND DEGRADATION OF SATRAPLATIN, JM118 AND CISPLATIN IN HUMAN PLASMAIN VITRO

scientific article published in July 2008

Can in vitro drug metabolism studies with human tissue replace in vivo animal studies? ⬇️

scientific article published on August 2, 2005

Circulating microRNA as biomarkers of clozapine-induced cardiotoxicity

scientific article published on 21 November 2019

Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection

scientific article published in October 1999

Drug-protein conjugates—XIV

scientific article published in January 1988

Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes

scientific article

Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes

scientific article published in June 1995

Gender differences in the metabolism and pharmacokinetics of the experimental anticancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).

scientific article published on 24 October 2001

Glucuronidation of anticancer prodrug PR-104A: species differences, identification of human UDP-glucuronosyltransferases, and implications for therapy

scientific article published on 22 March 2011

Gonadal influence on the metabolism and haematological toxicity of dapsone in the rat.

scientific article published in October 1990

Hepatic nitroreduction, toxicity and toxicokinetics of the anti-tumour prodrug CB 1954 in mouse and rat

scientific article published in October 2007

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid

scientific article published on August 2004

Identification and reactivity of the major metabolite (beta-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

scientific article published in May 2001

In vitro and in vivo kinetic interactions of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac

scientific article

In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations

scientific article published on 19 October 2008

In vivo metabolism of norbormide in rats and mice

scientific article published on 8 April 2009

Indirect regulation of CYP2C19 gene expression via DNA methylation.

scientific article published on 25 August 2017

Influence of mustard group structure on pathways of in vitro metabolism of anticancer N-(2-hydroxyethyl)-3,5-dinitrobenzamide 2-mustard prodrugs

scientific article published on 12 November 2007

Inhibition of Dapsone-Induced Methaemoglobinaemia by Cimetidine in the Rat During Chronic Dapsone Administration

scientific article published in March 1991

Inhibition of Dapsone-induced Methaemoglobinaemia by Cimetidine in the Presence of Trimethoprim in the Rat

scientific article published in February 1992

Measuring antibiotic levels and their relationship with the microbiome in chronic rhinosinusitis

scientific article published on 07 October 2019

Metabolic interactions with piperazine-based 'party pill' drugs

scientific article published in July 2009

Metabolism of praziquantel in kingfish Seriola lalandi

scientific article published in January 2008

Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans

scientific article published on 9 April 2004

Oral antibiotics used in the treatment of chronic rhinosinusitis have limited penetration into the sinonasal mucosa: a randomized trial

scientific article published on 25 August 2020

Pharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic Administration

scientific article published on 18 January 2017

Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria

scientific article published on 30 April 2013

Pharmacokinetics of cytisine, an α4β2nicotinic receptor partial agonist, in healthy smokers following a single dose

article

Rapid biotransformation of satraplatin by human red blood cells in vitro

scientific article published in July 2002

Regulating new psychoactive drugs: innovation leading to compromise

scientific article published on 13 August 2014

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

scientific article

Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro

scientific article published on 20 September 2005

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo

scientific article published in February 2002

Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry

scientific article published on 11 May 2006

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group

scientific article published in February 1997

Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides

scientific article published on 31 October 2013

Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides

scientific article published on 20 February 2014

Thalidomide pharmacokinetics and metabolite formation in mice, rabbits, and multiple myeloma patients

scientific article published in September 2004

The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: Chemical mechanisms and the effects of fluorine substitution

scientific article published in September 1995

The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation

scientific article published in December 2010

The effect of 2,2'-substitution on the metabolism and toxicity of dapsone in vitro and in vivo.

scientific article published in March 1998

The importance of correct assignment of CYP2B6 genetic variants with respect to cyclophosphamide metabolizer status ⬇️

scientific article published on 25 March 2011

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

scientific article (publication date: February 2002)

Use of a metabolic inhibitor to reduce dapsone-dependent haematological toxicity

scientific article published in 1992

Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans

scientific article published on 8 June 2010

Varenicline improves motor and cognitive symptoms in early Huntington's disease

scientific article published on 19 September 2016

Which CYP2B6 Variants Have Functional Consequences for Cyclophosphamide Bioactivation?

scientific article published on 8 December 2011

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