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List of works by Laura M. Bohn

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.

scientific article

Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.

scientific article

Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo

scientific article

Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology.

scientific article published on 26 November 2011

Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors

scientific article published on October 2002

Brain opioid receptor adaptation and expression after prenatal exposure to buprenorphine

scientific article published in November 1998

Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice

scientific article

Community guidelines for GPCR ligand bias: IUPHAR review 32

Constitutive trafficking--more than just running in circles?

scientific article published on 24 January 2007

Desensitization of G protein-coupled receptors and neuronal functions

scientific article published in January 2004

Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

scientific article published on December 2002

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

scientific article

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

scientific article

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

scientific article (publication date: 24 April 2003)

Drosophila CG8422 encodes a functional diuretic hormone receptor

scientific article published in February 2004

Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.

scientific article published in November 2003

Evidence for κ‐ and μ‐Opioid Receptor Expression in C6 Glioma Cells ⬇️

scientific article published on May 1, 1998

Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.

scientific article

G protein signaling–biased agonism at the κ-opioid receptor is maintained in striatal neurons

article

G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice.

scientific article published on January 2004

GIRK channel modulation by assembly with allosterically regulated RGS proteins ⬇️

scientific article published on November 19, 2012

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter

scientific article

Herkinorin analogues with differential beta-arrestin-2 interactions

scientific article

How Specific Are "Target-Specific" Drugs? Celecoxib as a Case in Point

scientific article published on 01 August 2006

Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions

scientific article published on 10 October 2003

Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways

scientific article

Kappa-opioid receptor binding varies inversely with tumor grade in human gliomas

scientific article published in December 1998

Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse.

scientific article

Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine

scientific article published on 23 December 2010

Morphine side effects in beta-arrestin 2 knockout mice

scientific article published on 25 May 2005

Mu opioid receptor regulation and opiate responsiveness

scientific article

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

scientific article published on 01 December 1999

Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer

scientific article

Opioid receptor signaling: relevance for gastrointestinal therapy

scientific article published on 28 August 2006

Pharmacological characterization of a selective agonist for bombesin receptor subtype-3.

scientific article published on 04 July 2009

Physiological and pharmacological implications of beta-arrestin regulation.

scientific article published on 06 December 2008

Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies

scientific article published on 6 February 2008

Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

scientific article

Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo

scientific article

Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon.

scientific article published on 29 January 2009

Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.

scientific article

Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.

scientific article

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.

scientific article

β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner

scientific article published on 20 January 2012

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