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List of works by Kathrin M. Bernt

A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.

scientific article published on 4 October 2006

A role for DOT1L inMLL-rearranged leukemias

scientific article published on 01 December 2011

A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases.

scientific article published on April 2004

AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.

scientific article

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.

scientific article

Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy.

scientific article published in May 2005

Bridging the Gaps: iPSC-Based Models from CHIP to MDS to AML.

scientific article published in March 2017

Chromatin-modifying enzymes as modulators of reprogramming

scientific article

Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia

scientific article

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.

scientific article

Epigenetic modifiers in normal and malignant hematopoiesis

scientific article published on January 2015

Eradication of CD19+ leukemia by targeted calicheamicin θ.

scientific article

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

scientific article

Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 16 February 2016

HDAC expression patterns in pediatric ALL ⬇️

scientific article published on August 17, 2013

Histone profiles in cancer

scientific article published on 22 July 2015

Human milk and the response of intestinal epithelium to infection

scientific article

Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug-resistant T-cell leukemia.

scientific article published on 6 March 2003

Inactivation of Eed impedes MLL-AF9-mediated leukemogenesis through Cdkn2a-dependent and Cdkn2a-independent mechanisms in a murine model

scientific article

JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes

scientific article published on 12 February 2020

Leukemia stem cells and human acute lymphoblastic leukemia.

scientific article published on January 2009

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l ⬇️

scientific article published on January 29, 2013

MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.

scientific article published on 09 February 2017

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

scientific article published in July 2011

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia

scientific article published on 29 February 2016

Mechanisms of Pinometostat (EPZ-5676) Treatment-Emergent Resistance in MLL-Rearranged Leukemia.

scientific article published on 20 April 2017

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

scientific article

Synthesis, hydrolytic activation and cytotoxicity of etoposide prodrugs

scientific article published in February 2002

Targeting Epigenetic Programs in MLL-Rearranged Leukemias ⬇️

scientific article published on January 1, 2011

The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and Opportunities

scientific article

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution

scientific article published on 28 March 2019

The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors.

scientific article published on November 2003

The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia

scientific article published on 16 May 2018

Transient potential receptor melastatin-2 (Trpm2) does not influence murine MLL-AF9-driven AML leukemogenesis or in vitro response to chemotherapy.

scientific article published on 23 March 2016

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