List of works by David Otaegui

A New Risk Variant for Multiple Sclerosis at 11q23.3 Locus Is Associated with Expansion of CXCR5+ Circulating Regulatory T Cells

scientific article published on 26 February 2020

A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.

scientific article

A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease

scientific article published on 01 October 2003

ABO blood group distributions in multiple sclerosis patients from Basque Country; O- as a protective factor

scientific article published on 01 October 2019

ANKRD55 and DHCR7 are novel multiple sclerosis risk loci

article

Age gene expression and coexpression progressive signatures in peripheral blood leukocytes.

scientific article published on 8 September 2015

Apolipoprotein E epsilon4 allele in familial and sporadic Parkinson's disease

scientific article published on 14 August 2006

Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients.

scientific article published on 28 August 2008

Blood Markers in Healthy-Aged Nonagenarians: A Combination of High Telomere Length and Low Amyloidβ Are Strongly Associated With Healthy Aging in the Oldest Old

scientific article published on 28 November 2018

Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients.

scientific article published on 22 May 2014

CD24 V/V is an allele associated with the risk of developing multiple sclerosis in the Spanish population

scientific article published on 01 August 2006

Cancer risk in DM1 is sex-related and linked to miRNA-200/141 downregulation.

scientific article published on 24 August 2016

Characterization of novel CAPN3 isoforms in white blood cells: an alternative approach for limb-girdle muscular dystrophy 2A diagnosis.

scientific article published on 19 June 2008

Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis

scientific article published on 19 December 2011

CircRNAs and cancer: Biomarkers and master regulators

scientific article published on 11 December 2018

Circular RNA profiling reveals that circular RNAs from ANXA2 can be used as new biomarkers for multiple sclerosis

scientific article published on 23 June 2017

Circulating microparticles reflect treatment effects and clinical status in multiple sclerosis

scientific article published on 01 January 2014

Cognitive function in facioscapulohumeral dystrophy correlates with the molecular defect.

scientific article published on 22 September 2008

Cognitive performance and quality of life in multiple sclerosis in Gipuzkoa

scientific article

Cognitive/personality pattern and triplet expansion size in adult myotonic dystrophy type 1 (DM1): CTG repeats, cognition and personality in DM1.

scientific article published on 23 July 2009

Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study

scientific article published on 23 January 2015

Differential micro RNA expression in PBMC from multiple sclerosis patients

scientific article

ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential.

scientific article published on 6 February 2008

Editorial: Novel Clinical Applications of Extracellular Vesicles

scientific article published on 24 July 2015

Expression Profiling Analysis Reveals Key MicroRNA-mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa.

scientific article

Extracellular Vesicles in Multiple Sclerosis: What are They Telling Us?

scientific article

Ferritin-mediated siRNA delivery and gene silencing in human tumor and primary cells.

scientific article published on 5 May 2016

Fine mapping and functional analysis of the multiple sclerosis risk gene CD6

scientific article

Genes related to iron metabolism and susceptibility to Alzheimer's disease in Basque population

scientific article published on 02 October 2006

Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk.

scientific article published on 12 January 2013

HLA-DRB1*15:01 and multiple sclerosis: a female association?

scientific article published on 29 November 2011

Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis

scientific article published on 17 November 2012

Identification of ncRNAs as potential therapeutic targets in multiple sclerosis through differential ncRNA - mRNA network analysis.

scientific article

Increased transcriptional activity of milk-related genes following the active phase of experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article published in September 2007

Inflammaging and Frailty Status Do Not Result in an Increased Extracellular Vesicle Concentration in Circulation.

scientific article published on 20 July 2016

Influence of CCR5-Delta32 genotype in Spanish population with multiple sclerosis

scientific article published on 10 March 2007

LGMD2A: genotype-phenotype correlations based on a large mutational survey on the calpain 3 gene.

scientific article published on 2 February 2005

Liquid Biopsy in Glioblastoma: Opportunities, Applications and Challenges

scientific article published on 05 July 2019

Longitudinal clinical follow-up of a large family with the R357P Twinkle mutation.

scientific article

Methods for extracellular vesicles isolation in a hospital setting.

scientific article published on 13 February 2015

Minimizing creatine kinase variability in rats for neuromuscular research purposes

scientific article

Mitochondrial DNA depletion: mutations in thymidine kinase gene with myopathy and SMA.

scientific article published in October 2002

Mitochondrial haplogroups in Basque multiple sclerosis patients

scientific article published on 01 October 2004

Mitochondrial polymporphisms in Parkinson's Disease

scientific article published on 01 November 2004

Models for Studying Myelination, Demyelination and Remyelination

scientific article

Molecular characterization of putative modulatory factors in two Spanish families with A1555G deafness

scientific article published on 07 April 2008

Mutations in progranulin gene: clinical, pathological, and ribonucleic acid expression findings.

scientific article

Neural-competent cells of adult human dermis belong to the Schwann lineage

scientific article published on 16 October 2014

Neurogenetic disorders in the Basque population

scientific article

Open Access of COVID-19-related publications in the first quarter of 2020: a preliminary study based in PubMed

scientific article published on 26 June 2020

Open Access of COVID-19-related publications in the first quarter of 2020: a preliminary study based in PubMed

scientific article published on 12 August 2020

Penetrance in Parkinson's disease related to the LRRK2 R1441G mutation in the Basque country (Spain).

scientific article published on October 2010

Progressive changes in non-coding RNA profile in leucocytes with age.

scientific article published on 27 April 2017

Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.

scientific article published on 14 October 2010

Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes

article

SncRNA (microRNA &snoRNA) opposite expression pattern found in multiple sclerosis relapse and remission is sex dependent.

scientific article published on February 2016

Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene

article

Study of mitochondrial DNA mutations in patients with migraine with prolonged aura

scientific article published on 01 July 2004

T cells and immune functions of plasma extracellular vesicles are differentially modulated from adults to centenarians

scientific article published on 27 November 2019

TACI mutation in Good's Syndrome: in search of a genetic basis

scientific article published on 04 August 2012

The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

scientific article published on 19 August 2018

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

scientific article published on 10 January 2020

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis

scientific article published on 27 May 2010

The circulating transcriptome as a source of cancer liquid biopsy biomarkers

scientific article published on 23 January 2019

The circulating transcriptome as a source of non-invasive cancer biomarkers: concepts and controversies of non-coding and coding RNA in body fluids

scientific article

The genetics of multiple sclerosis: review of current and emerging candidates

scientific article

Therapeutic Potential of Extracellular Vesicles for Demyelinating Diseases; Challenges and Opportunities

scientific article published on 23 November 2018

To Be or Not to Be: Circular RNAs or mRNAs From Circular DNAs?

scientific article published on 11 October 2019

Transcriptomic profile reveals gender-specific molecular mechanisms driving multiple sclerosis progression

scientific article

UCP2 and mitochondrial haplogroups as a multiple sclerosis risk factor

scientific article published on 09 February 2007

Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.

scientific article published on 23 September 2010

Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.

scientific article published on 28 April 2010

Whole-Transcriptome Analysis in Peripheral Blood Mononuclear Cells from Patients with Lipid-Specific Oligoclonal IgM Band Characterization Reveals Two Circular RNAs and Two Linear RNAs as Biomarkers of Highly Active Disease

scientific article published on 26 November 2020

X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1 ⬇️

scientific article

Yerba mate (Ilex paraguariensis) inhibits lymphocyte activation in vitro

scientific article published on 7 October 2016

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