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List of works by George R. Dubyak

Activation of calcium mobilization and calcium influx by alpha 1-adrenergic receptors in a smooth muscle cell line

scientific article

Activation of the inositol phospholipid signaling system by receptors for extracellular ATP in human neutrophils, monocytes, and neutrophil/monocyte progenitor cells

scientific article published on 01 January 1988

Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.

scientific article published on 6 July 2016

Adenosine triphosphate activates the phospholipase-C cascade system in human amnion cells without increasing prostaglandin production

scientific article published in April 1989

Agonist-induced calcium transients in cultured smooth muscle cells: measurements with fura-2 loaded monolayers

scientific article published on 01 May 1986

Antipyrylazo III, a "middle range" Ca2+ metallochromic indicator

scientific article published on 01 April 1978

Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells.

scientific article published on 04 February 2009

Basal and inducible expression of the thiol-sensitive ART2.1 ecto-ADP-ribosyltransferase in myeloid and lymphoid leukocytes

scientific article published on 30 April 2009

Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on "A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP".

scientific article published in February 2009

CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy

scientific article published on 29 July 2016

Calcium currents in the A7r5 smooth muscle-derived cell line

scientific article published on December 1990

Calcium is a key signaling molecule in beta-lapachone-mediated cell death

scientific article

Calcium-independent phospholipase A2 beta is dispensable in inflammasome activation and its inhibition by bromoenol lactone.

scientific article published on January 2009

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling

scientific article

Charge of the mito brigade. Focus on “Changes in mitochondrial surface charge mediate recruitment of signaling molecules during apoptosis” ⬇️

scientific article published on November 10, 2010

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis

scientific article published on 01 August 2018

Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism

scientific article

Chemotherapy engages multiple pathways leading to IL-1β production by myeloid leukocytes.

scientific article published on 3 January 2014

Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes.

scientific article published on 8 April 2003

Decreased protein kinase C activity during cerebral ischemia and after reperfusion in the adult rat.

scientific article published in December 1990

Differential regulation of P2X7 receptor activation by extracellular nicotinamide adenine dinucleotide and ecto-ADP-ribosyltransferases in murine macrophages and T cells.

scientific article published on July 2009

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria

scientific article published on 9 May 2007

Dueling nucleosides: cross-regulation of extracellular adenosine by guanosine. Focus on “Extracellular guanosine regulates extracellular adenosine levels” ⬇️

scientific article published on January 16, 2013

Effect of atrial natriuretic factor on cytosolic free calcium in rat glomerular mesangial cells

scientific article

Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells

scientific article published on 01 May 1993

Effects of 12-O-tetradecanoyl-phorbol-13-acetate on Myofibril integrity and Ca2+ content in developing myotubes

scientific article published on 01 February 1982

Effects of sea nettle toxin on glucose transport in hamster intestine

scientific article published on 01 December 1974

Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of Gq-coupled 5-HT2A receptors and Gs-coupled 5-HT7A receptors in PC12 cells

scientific article published in January 2005

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

scientific article

Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells

scientific article published on 01 February 1986

Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle ⬇️

scientific article published on April 13, 2011

Flow cytometric measurements of cytosolic [Ca2+] in normal and leukemic progenitor cells

scientific article published on 01 January 1988

Function without form: an ongoing search for maxi-anion channel proteins. Focus on “Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells” ⬇️

scientific article published on August 29, 2012

Functional expression of the parathyroid cell calcium receptor in Xenopus oocytes

scientific article published in October 1993

Functionalized congeners of tyrosine-based P2X(7) receptor antagonists: probing multiple sites for linking and dimerization

scientific article published on September 2002

Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels

scientific article

Human epidermal keratinocytes undergo (-)-epigallocatechin-3-gallate-dependent differentiation but not apoptosis

scientific article

Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7.

scientific article

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.

scientific article

IKKα negatively regulates ASC-dependent inflammasome activation

scientific article

Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity

scientific article published on 01 May 1997

Inhibition of tension development and actomyosin ATPase activity in barnacle muscle by the Ca2+-indicator dye antipyrylazo III.

scientific article published on June 1985

Intracellular calcium changes trigger connexin 32 hemichannel opening ⬇️

scientific article published on 8 December 2005

Ion homeostasis, channels, and transporters: an update on cellular mechanisms

scientific article

K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling

scientific article

Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells.

scientific article

Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV.

scientific article

Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

scientific article published on 24 December 2003

Microbes mediate mitochondrial misinformation to misguide neutrophils

scientific article published on 21 October 2019

Modification of β-Defensin-2 by Dicarbonyls Methylglyoxal and Glyoxal Inhibits Antibacterial and Chemotactic Function In Vitro

scientific article

Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation

scientific article published on 13 September 2010

NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx.

scientific article published on 11 May 2016

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux

scientific article

Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.

scientific article published on 15 February 2016

Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease

scientific article

Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms ⬇️

scientific article published on October 1, 2003

Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells

scientific article published on 01 October 1988

P2-purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells

scientific article published on 01 July 1990

P2X7 receptor regulation of non-classical secretion from immune effector cells

scientific article published on 24 August 2012

P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways

scientific article

Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation

scientific article published on 20 April 2011

Phosphorus-31 nuclear magnetic resonance studies of single muscle cells isolated from barnacle depressor muscle

scientific article published on 01 July 1983

Potent P2X7 Receptor Antagonists: Tyrosyl Derivatives Synthesized Using a Sequential Parallel Synthetic Approach

scientific article published on October 2001

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells

scientific article published on 27 September 2013

Purinergic Receptors: Key Mediators of HIV-1 Infection and Inflammation

scientific article

Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1 ⬇️

scientific article published on August 10, 2011

Rapid effects of phorbol ester on platelet shape change, cytoskeleton and calcium transient

scientific article published on 01 October 1986

Reciprocal Changes in Phosphoenolpyruvate Carboxykinase and Pyruvate Kinase with Age Are a Determinant of Aging in Caenorhabditis elegans

scientific article

Renal sugar transport in the winter flounder. IV. Effect of Ca2+ on sugar transport in teased renal tubules

scientific article published in October 1977

Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.

scientific article

Sarcoplasmic Ca2+ transients during the contractile cycle of single barnacle muscle fibres: measurements with arsenazo III-injected fibres

scientific article published on 01 March 1982

Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X.

scientific article

Stimulation of cytosolic free calcium and inositol phosphates by prostaglandins in cultured rat mesangial cells

scientific article published on 01 January 1987

Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors

scientific article

Sulfated signal from ASJ sensory neurons modulates stomatin-dependent coordination in Caenorhabditis elegans

scientific article published on 13 September 2006

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

scientific article published on 21 March 2016

The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation

scientific article published on 8 February 2008

The phlorizin effect on the transport of sugars at the antiluminal face of teased flounder tubules

scientific article published on 01 March 1977

The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes.

scientific article published on 17 October 2013

Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes.

scientific article

Up-regulated Ectonucleotidases in Fas-Associated Death Domain Protein- and Receptor-Interacting Protein Kinase 1-Deficient Jurkat Leukemia Cells Counteract Extracellular ATP/AMP Accumulation via Pannexin-1 Channels during Chemotherapeutic Drug-Induc

scientific article published in May 2017

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