List of works - Robert H. Lipsky

A dinucleotide repeat in the third intron of CD36

scientific article published on 01 January 1994

A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder

scientific article

A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating

scientific article published on 31 October 2002

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression

scientific journal article

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate

scientific article published in November 1998

Additional functional variation at the SLC6A4 gene

scientific article published on January 2009

Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic?

scientific article

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression

scientific article published in July 2007

Association of COMT Val158Met genotype with executive functioning following traumatic brain injury

scientific article published in January 2005

Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort

scientific article

Association of cystathionine beta-synthase polymorphisms and aneurysmal subarachnoid hemorrhage

scientific article published on 4 August 2017

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations

scientific article

Associations of Endothelin Polymorphisms and Aneurysm Size at Time of Rupture

scientific article published on 16 March 2017

Authors' reply

BDNF polymorphism-dependent OFC and DLPFC plasticity differentially moderates implicit and explicit bias

scientific article

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects

scientific article published on July 2005

BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability.

scientific article

Brain adaptation to stressful stimuli: a new perspective on potential therapeutic approaches based on BDNF and NMDA receptors

scientific article published on October 2008

Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity

scientific article published on December 2007

Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation.

scientific article published in July 2005

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

scientific article published on 22 July 2013

CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques

scientific article published on August 2008

Cellular and molecular responses of cultured neurons to stressful stimuli

scientific article

Changes in nuclear proteins of astrocytes as a result of acute ammonia or ethanol exposure

scientific article

Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species

scientific article published in April 1980

Characterization of human cDNA and genomic clones for glial fibrillary acidic protein

scientific article

Characterization of two alternatively spliced 5'-untranslated exons of the human CD36 gene in different cell types

scientific article published on November 1993

Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-D-aspartate and TrkB receptors in cerebellar granule cell neurons

scientific article published in January 2002

Correlates of posttraumatic epilepsy 35 years following combat brain injury.

scientific article

Delineating and understanding cerebellar neuroprotective pathways: potential implication for protecting the cortex

scientific article

Demographic, structural and genetic predictors of late cognitive decline after penetrating head injury

scientific article published on 19 December 2007

Determination of melting temperature for variant detection using dHPLC: a comparison between an empirical approach and DNA melting prediction software

scientific article

Differences in nuclear proteins of neurons, astrocytes and C-6 glioma cells

scientific article

Differential actions of ethanol and trichloroethanol at sites in the M3 and M4 domains of the NMDA receptor GluN2A (NR2A) subunit.

scientific article published on 25 September 2009

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay

scientific article

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

scientific article

Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1.

scientific article published on 23 March 2009

Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons

scientific article published on June 2010

Epigenetic mechanisms regulating learning and long‐term memory ⬇️

scientific article published on November 6, 2012

Epigenetics of depression

scientific article

Estimation of Haplotypes at DRD2 May Have Produced Misleading Results—Reply

Evidence that the B2 chain of laminin is responsible for the neurite outgrowth-promoting activity of astrocyte extracellular matrix

scientific article

Genetic predictors of outcome following traumatic brain injury.

scientific article

Genetic variation in human NPY expression affects stress response and emotion

scientific article published on 02 April 2008

Genomics and variation of ionotropic glutamate receptors

scientific article published on November 2003

Genomics and variation of ionotropic glutamate receptors: implications for neuroplasticity

scientific article published on 18 February 2005

Haplotype architecture of the norepinephrine transporter gene SLC6A2 in four populations

scientific article published in January 2004

Haplotype structure of the beta adrenergic receptor genes in US Caucasians and African Americans

scientific article published in March 2005

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene

scientific article published on 8 December 2004

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations

scientific article

Hormesis: a promising strategy to sustain endogenous neuronal survival pathways against neurodegenerative disorders

scientific article published on 24 August 2007

Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution

scientific article

Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway

scientific article published on 01 January 2004

Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus.

scientific article

Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes

scientific article published on April 2009

Mutations at F637 in the NMDA receptor NR2A subunit M3 domain influence agonist potency, ion channel gating and alcohol action

scientific article

N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway

scientific article

NMDA receptor activation induces differential epigenetic modification of Bdnf promoters in hippocampal neurons

scientific article

Oxytocin receptor genetic variation promotes human trust behavior.

scientific article published on 2 February 2012

Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans

scientific article published on 21 September 2014

Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16.

scientific article

Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder

scientific article

Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor

scientific article published on April 2004

Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke.

scientific article published on 29 July 2009

The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

scientific article published on 11 January 2008

The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons

scientific article published on 5 July 2005

The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage

scientific article published on 24 October 2017

The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury

scientific article

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment

scientific article

Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome

scientific article

Zhou et al. reply

scientific article published in Nature

List of works by Robert H. Lipsky

A dinucleotide repeat in the third intron of CD36

A missense variant (P10L) of the melanopsin (OPN4) gene in seasonal affective disorder

A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating

AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate

Additional functional variation at the SLC6A4 gene

Alpha-linolenic acid: an omega-3 fatty acid with neuroprotective properties-ready for use in the stroke clinic?

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression

Association of COMT Val158Met genotype with executive functioning following traumatic brain injury

Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort

Association of cystathionine beta-synthase polymorphisms and aneurysmal subarachnoid hemorrhage

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations

Associations of Endothelin Polymorphisms and Aneurysm Size at Time of Rupture

Authors' reply

BDNF polymorphism-dependent OFC and DLPFC plasticity differentially moderates implicit and explicit bias

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects

BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability.

Brain adaptation to stressful stimuli: a new perspective on potential therapeutic approaches based on BDNF and NMDA receptors

Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity

Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation.

CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response

CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques

Cellular and molecular responses of cultured neurons to stressful stimuli

Changes in nuclear proteins of astrocytes as a result of acute ammonia or ethanol exposure

Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species

Characterization of human cDNA and genomic clones for glial fibrillary acidic protein

Characterization of two alternatively spliced 5'-untranslated exons of the human CD36 gene in different cell types

Co-activation of the phosphatidylinositol-3-kinase/Akt signaling pathway by N-methyl-D-aspartate and TrkB receptors in cerebellar granule cell neurons

Correlates of posttraumatic epilepsy 35 years following combat brain injury.

Delineating and understanding cerebellar neuroprotective pathways: potential implication for protecting the cortex

Demographic, structural and genetic predictors of late cognitive decline after penetrating head injury

Determination of melting temperature for variant detection using dHPLC: a comparison between an empirical approach and DNA melting prediction software

Differences in nuclear proteins of neurons, astrocytes and C-6 glioma cells

Differential actions of ethanol and trichloroethanol at sites in the M3 and M4 domains of the NMDA receptor GluN2A (NR2A) subunit.

Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1.

Effects of histone deacetylase inhibitor Trichostatin A on epigenetic changes and transcriptional activation of Bdnf promoter 1 by rat hippocampal neurons

Epigenetic mechanisms regulating learning and long‐term memory ⬇️

Epigenetics of depression

Estimation of Haplotypes at DRD2 May Have Produced Misleading Results—Reply

Evidence that the B2 chain of laminin is responsible for the neurite outgrowth-promoting activity of astrocyte extracellular matrix

Genetic predictors of outcome following traumatic brain injury.

Genetic variation in human NPY expression affects stress response and emotion

Genomics and variation of ionotropic glutamate receptors

Genomics and variation of ionotropic glutamate receptors: implications for neuroplasticity

Haplotype architecture of the norepinephrine transporter gene SLC6A2 in four populations

Haplotype structure of the beta adrenergic receptor genes in US Caucasians and African Americans

Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations

Hormesis: a promising strategy to sustain endogenous neuronal survival pathways against neurodegenerative disorders

Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution

Inhibition of protein kinase C promotes neuronal survival in low potassium through an Akt-dependent pathway

Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus.

Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes

Mutations at F637 in the NMDA receptor NR2A subunit M3 domain influence agonist potency, ion channel gating and alcohol action

N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway

NMDA receptor activation induces differential epigenetic modification of Bdnf promoters in hippocampal neurons

Oxytocin receptor genetic variation promotes human trust behavior.

Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans

Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16.

Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder

Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor

Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: a versatile potential therapy for stroke.

The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons

The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage

The role of the Met66 brain-derived neurotrophic factor allele in the recovery of executive functioning after combat-related traumatic brain injury

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment

Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome

Zhou et al. reply