List of works - Mark V. Boekschoten

A Robust Auxin Response Network Controls Embryo and Suspensor Development through a Basic Helix Loop Helix Transcriptional Module

scientific article published on 20 December 2018

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences

scientific article (publication date: 2010)

A weekly alternating diet between caloric restriction and medium fat protects the liver from fatty liver development in middle-aged C57BL/6J mice.

scientific article

Absorption, distribution, and biliary excretion of cafestol, a potent cholesterol-elevating compound in unfiltered coffees, in mice

scientific article published on 4 January 2010

Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice.

scientific article published on 21 September 2010

An 8-week high-fat diet induces obesity and insulin resistance with small changes in the muscle transcriptome of C57BL/6J mice

scientific article published in January 2009

An acute intake of plant stanol esters alters immune-related pathways in the jejunum of healthy volunteers.

scientific article published on 16 February 2015

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

scientific article

Coffee bean extracts rich and poor in kahweol both give rise to elevation of liver enzymes in healthy volunteers

scientific article

Coffee oil consumption increases plasma levels of 7alpha-hydroxy-4-cholesten-3-one in humans

scientific article published on 01 April 2005

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

scientific article published on 18 December 2015

Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice

scientific article published on 27 September 2011

Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine

scientific article

Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart

article

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

scientific article published on 22 May 2011

Dietary heme induces acute oxidative stress, but delayed cytotoxicity and compensatory hyperproliferation in mouse colon

scientific article published in March 2013

Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

scientific article

Differential regulation of pancreatic digestive enzymes during chronic high-fat diet-induced obesity in C57BL/6J mice

scientific article

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice

scientific article

Erratum: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance

scientific article published on 12 January 2015

Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness

scientific article published on 2 February 2016

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

scientific article published on 2 May 2014

Global testing of shifts in metabolic phenotype

scientific article published on 04 October 2018

Gut bacteria-host metabolic interplay during conventionalisation of the mouse germfree colon.

scientific article published on 22 November 2012

Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury

scientific article published on 27 August 2014

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

scientific article published on 6 May 2013

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice

scientific article

Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways

scientific article

Hypothalamic food intake regulation in a cancer-cachectic mouse model.

scientific article published on 13 November 2013

IL-22-STAT3 pathway plays a key role in the maintenance of ileal homeostasis in mice lacking secreted mucus barrier.

scientific article published on March 2015

IL-37 protects against obesity-induced inflammation and insulin resistance

scientific article published on 3 September 2014

In Male Rats with Concurrent Iron and (n-3) Fatty Acid Deficiency, Provision of Either Iron or (n-3) Fatty Acids Alone Alters Monoamine Metabolism and Exacerbates the Cognitive Deficits Associated with Combined Deficiency ⬇️

scientific article published on June 27, 2012

Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome

scientific article

Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress

scientific article

Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice.

scientific article published in May 2018

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

scientific article published on 13 September 2013

LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux

scientific article

Maternal High-fat Diet Accelerates Development of Crohn's Disease-like Ileitis in TNFΔARE/WT Offspring.

scientific article published on September 2015

Maternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspring

scientific article

Maternal exposure to a Western-style diet causes differences in intestinal microbiota composition and gene expression of suckling mouse pups.

scientific article published on 30 April 2016

Metabolic switching of human myotubes is improved by n-3 fatty acids

scientific article

Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis

scientific article published on 29 November 2010

PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.

scientific article

PUFAs acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increase postprandial insulin sensitivity

scientific article published on 15 February 2012

Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase

scientific article published on 13 July 2012

Plant development. Integration of growth and patterning during vascular tissue formation in Arabidopsis

scientific article published in August 2014

Pronounced effects of acute endurance exercise on gene expression in resting and exercising human skeletal muscle.

scientific article

Reproducibility of the serum lipid response to coffee oil in healthy volunteers

scientific article

Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

scientific article

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

scientific article

Short-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice

scientific article published on 27 November 2007

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

scientific article

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

scientific article published on 9 August 2013

The Muscle Metabolome Differs between Healthy and Frail Older Adults.

scientific article published on 6 January 2016

The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

scientific article (publication date: 26 November 2008)

The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors

scientific article

The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men.

scientific article published on 20 August 2013

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way.

scientific article

The role of epoxidation and electrophile-responsive element-regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol

scientific article

Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.

scientific article published on 15 December 2009

Which are the greatest recent discoveries and the greatest future challenges in nutrition?

scientific article published on 10 October 2007

[Negligible amounts of cholesterol-raising diterpenes in coffee made with coffee pads in comparison with unfiltered coffee]

scientific article published on 01 December 2006

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice

scientific article published on 5 February 2009

p21 ablation in liver enhances DNA damage, cholestasis, and carcinogenesis

scientific article published on 21 January 2015

List of works by Mark V. Boekschoten

A Robust Auxin Response Network Controls Embryo and Suspensor Development through a Basic Helix Loop Helix Transcriptional Module

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences

A weekly alternating diet between caloric restriction and medium fat protects the liver from fatty liver development in middle-aged C57BL/6J mice.

Absorption, distribution, and biliary excretion of cafestol, a potent cholesterol-elevating compound in unfiltered coffees, in mice

Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice.

An 8-week high-fat diet induces obesity and insulin resistance with small changes in the muscle transcriptome of C57BL/6J mice

An acute intake of plant stanol esters alters immune-related pathways in the jejunum of healthy volunteers.

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

Coffee bean extracts rich and poor in kahweol both give rise to elevation of liver enzymes in healthy volunteers

Coffee oil consumption increases plasma levels of 7alpha-hydroxy-4-cholesten-3-one in humans

Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.

Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice

Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine

Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

Dietary heme induces acute oxidative stress, but delayed cytotoxicity and compensatory hyperproliferation in mouse colon

Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

Differential regulation of pancreatic digestive enzymes during chronic high-fat diet-induced obesity in C57BL/6J mice

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice

Erratum: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance

Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

Global testing of shifts in metabolic phenotype

Gut bacteria-host metabolic interplay during conventionalisation of the mouse germfree colon.

Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury

Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice

Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways

Hypothalamic food intake regulation in a cancer-cachectic mouse model.

IL-22-STAT3 pathway plays a key role in the maintenance of ileal homeostasis in mice lacking secreted mucus barrier.

IL-37 protects against obesity-induced inflammation and insulin resistance

In Male Rats with Concurrent Iron and (n-3) Fatty Acid Deficiency, Provision of Either Iron or (n-3) Fatty Acids Alone Alters Monoamine Metabolism and Exacerbates the Cognitive Deficits Associated with Combined Deficiency ⬇️

Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome

Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress

Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice.

Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux

Maternal High-fat Diet Accelerates Development of Crohn's Disease-like Ileitis in TNFΔARE/WT Offspring.

Maternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspring

Maternal exposure to a Western-style diet causes differences in intestinal microbiota composition and gene expression of suckling mouse pups.

Metabolic switching of human myotubes is improved by n-3 fatty acids

Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis

PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.

PUFAs acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increase postprandial insulin sensitivity

Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase

Plant development. Integration of growth and patterning during vascular tissue formation in Arabidopsis

Pronounced effects of acute endurance exercise on gene expression in resting and exercising human skeletal muscle.

Reproducibility of the serum lipid response to coffee oil in healthy volunteers

Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

Short-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

The Muscle Metabolome Differs between Healthy and Frail Older Adults.

The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation

The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors

The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men.

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way.

The role of epoxidation and electrophile-responsive element-regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol

Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.

Which are the greatest recent discoveries and the greatest future challenges in nutrition?

[Negligible amounts of cholesterol-raising diterpenes in coffee made with coffee pads in comparison with unfiltered coffee]

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice

p21 ablation in liver enhances DNA damage, cholestasis, and carcinogenesis