Search filters

List of works by Caroline L. Relton

25-Hydroxyvitamin D in pregnancy and genome wide cord blood DNA methylation in two pregnancy cohorts (MoBa and ALSPAC).

scientific article published on 4 March 2016

A Methylome-Wide Association Study of Trajectories of Oppositional Defiant Behaviors and Biological Overlap With Attention Deficit Hyperactivity Disorder

scientific article published on 20 September 2017

A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data

scientific article published on 17 July 2019

A common variant in the PTPN11 gene contributes to the risk of tetralogy of Fallot.

scientific article published on 13 April 2012

A prospective study of one-carbon metabolism biomarkers and cancer of the head and neck and esophagus

A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57

scientific article published on 18 February 2019

A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk

scientific article published on 27 March 2013

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

scientific article published on 10 January 2020

AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality

scientific article published on 18 January 2017

Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome

scientific article published on 01 January 2015

Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children

scientific article published on 06 November 2019

Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception.

scientific article

Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study

scientific article

Alternative COVID-19 mitigation measures in school classrooms: analysis using an agent-based model of SARS-CoV-2 transmission

scholarly article

Alternative Covid-19 mitigation measures in school classrooms: analysis using an agent-based model of SARS-CoV-2 transmission

preprint

An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication

scientific article published on 18 February 2016

An epigenome-wide association study meta-analysis of educational attainment.

scientific article

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

scientific article published on 01 June 2019

An investigation of folate-related genetic factors in the determination of birthweight

scientific article

Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer

scientific article published in May 2022

Appraising the causal relevance of DNA methylation for risk of lung cancer

Appraising the causal relevance of DNA methylation for risk of lung cancer

scientific article published on 01 October 2019

Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

scientific article published on 07 August 2019

Approaches for drawing causal inferences from epidemiological birth cohorts: a review

scientific article published on 26 September 2014

Approaches for strengthening causal inference regarding prenatal risk factors for childhood behavioural and psychiatric disorders

scientific article published on October 2013

Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort.

scientific article published in November 2017

Assessing the Role of DNA Methylation-Derived Neutrophil-to-Lymphocyte Ratio in Rheumatoid Arthritis

article

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

scientific article published on 29 March 2022

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling.

scientific article

Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer

scientific article published on 01 February 2020

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

scientific article

Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort

scientific article published in August 2023

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts

scientific article published on 01 July 2021

Associations between high blood pressure and DNA methylation

scientific article published on 30 January 2020

Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

scientific article published in January 2021

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

scientific article published on 14 December 2018

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

scientific article published in Nature Communications

BMI trajectory in childhood is associated with asthma incidence at young adulthood mediated by DNA methylation

scientific article published on 23 July 2021

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

scientific article published on 9 March 2016

Bioinformatic selection of putative epigenetically regulated loci associated with obesity using gene expression data

scientific article

Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation

scientific article

Birth weight and early socio-economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49-51 years

scientific article published on 10 November 2010

Breastfeeding effects on DNA methylation in the offspring: A systematic literature review

scientific article published on 03 March 2017

Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach

scientific article published on 29 January 2020

Challenges and novel approaches for investigating molecular mediation.

scientific article published on 20 July 2016

Chance, choice and cause in cancer aetiology: individual and population perspectives

scientific article

Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures

scientific article published on 02 December 2019

Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans

scientific article published on 15 October 2022

Characterization of whole-genome autosomal differences of DNA methylation between men and women

scientific article

Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight

scientific article published on 12 January 2021

Childhood adversity and DNA methylation in two population-based cohorts

scientific article published on 03 December 2018

Chromosome 18 Loss of Heterozygosity in Small Intestinal Neuroendocrine Tumours: Multi-Omic and Tumour Composition Analyses

scientific article published on 10 March 2023

Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3).

scientific article published in January 2018

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

scientific article published on 23 October 2018

Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis

Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival

scientific article

Circulating biomarkers of tryptophan and the kynurenine pathway and lung cancer risk

scientific article published on 19 December 2013

Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations

scientific article

Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)

scientific article published on 22 July 2019

Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort

scientific article

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

scientific article published on 13 September 2017

Cohort profile: the Gateshead Millennium Study

scientific article

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

scientific article published on 24 August 2016

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

scientific article published on 19 September 2019

Complex trait methylation scores in the prediction of major depressive disorder

scientific article published in 2022

Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/2021 academic year

scientific article published on 3 June 2021

DNA Methylation Signatures of Breastfeeding in Buccal Cells Collected in Mid-Childhood

scientific article published on 17 November 2019

DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework.

scientific article published on 9 February 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

scientific article published on 30 March 2016

DNA Methylome Marks of Exposure to Particulate Matter at Three Time Points in Early Life

scientific article published on 30 March 2018

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

scientific article published on 25 November 2020

DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence.

scientific article published on 06 December 2016

DNA methylation as a marker for prenatal smoke exposure in adults

DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia

scientific article published on April 2016

DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium

scientific article published in March 2022

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

scientific article published on 15 September 2016

DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival

article published in 2018

DNA methylation from birth to late adolescence and development of multiple-risk behaviours

scientific article published on 15 November 2017

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

scientific article published on 01 July 2019

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

scientific article

DNA methylation patterns in cord blood DNA and body size in childhood

scientific article (publication date: 2012)

DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort

scientific article

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

scientific article published on 31 March 2022

DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers

scientific article

Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES).

scientific article published on 19 May 2015

Deriving the Dietary Approaches to Stop Hypertension (DASH) Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium

scientific article published on 08 November 2019

Dietary Quality and Dietary Inflammatory Potential During Pregnancy and Offspring Emotional and Behavioral Symptoms in Childhood: An Individual Participant Data Meta-analysis of Four European Cohorts

scientific article published on 24 October 2020

Differences in smoking associated DNA methylation patterns in South Asians and Europeans

scientific article published on 03 February 2014

Differential methylation of the type 2 diabetes susceptibility locus KCNQ1 is associated with insulin sensitivity and is predicted by CpG site specific genetic variation

Distinct DNA methylation profiles in subtypes of orofacial cleft.

scientific article

Do Depression and Stressful Events Cause Premature Aging?

scientific article published on 01 August 2018

Early-life dietary and epigenetic influences on childhood musculoskeletal health: Update on the UK component of the ALPHABET project

scientific article published on 8 May 2018

Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study.

scientific article

Epigenetic Regulation of Associates With Myocardial Infarction and Platelet Function

scientific article published on 4 February 2022

Epigenetic clocks and research implications of the lack of data on whom they have been developed: a review of reported and missing sociodemographic characteristics

scientific article published in January 2023

Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment

scientific article

Epigenetic gestational age acceleration: a prospective cohort study investigating associations with familial, sociodemographic and birth characteristics.

scientific article

Epigenetic profiling of ADHD symptoms trajectories: a prospective, methylome-wide study

scientific article published on 24 May 2016

Epigenetics and Orofacial Clefts

scientific article published on 26 February 2018

Epigenetics and child health: basic principles.

scientific article published on 23 July 2010

Epigenetics and noncommunicable diseases

scientific article published on 19 May 2017

Epigenetics, epidemiology and mitochondrial DNA diseases ⬇️

scientific article published on January 28, 2012

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

scientific article published on 24 July 2019

Epigenome-wide association study of asthma and wheeze in childhood and adolescence

scientific article published on 13 October 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Epigenome-wide association study of seizures in childhood and adolescence

scientific article published on 08 January 2020

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

scientific article published in December 2018

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

scientific article published on 02 March 2020

Epigenomics of being bullied: changes in DNA methylation following bullying exposure

scientific article published on 28 January 2020

Erratum: Whole-genome sequence-based analysis of thyroid function

scientific article published on 20 May 2015

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

scientific article published on 15 March 2023

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate.

scientific article published on 14 January 2019

Exploring a causal role of DNA methylation in the relationship between maternal vitamin B12 during pregnancy and child's IQ at age 8, cognitive performance and educational attainment: a two-step Mendelian randomization study.

scientific article

Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post-natal environmental exposures and risk of childhood acute lymphoblastic leukaemia

scientific article published on 19 March 2019

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans

scientific article published on 11 January 2018

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

scientific article

Filaggrin null mutations and childhood atopic eczema: A population-based case-control study

article

Folic acid supplementation and social deprivation.

scientific article

From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive

scientific article published on August 2015

Genetic and non-genetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12

scientific article

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma

scientific article published on 01 April 2019

Genetic epidemiologic studies of preterm birth: guidelines for research

scientific article published on February 2007

Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.

scientific article published on 23 August 2011

Genetic selection? A study of individual variation in the enzymes of folate metabolism

scientific article

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

scientific article

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

scientific article

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

scientific article published on 3 January 2018

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

scientific article published on 15 August 2018

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Gestational route to healthy birth (GaRBH): protocol for an Indian prospective cohort study

scientific article published on 01 May 2019

Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles

scientific article published in February 2012

Growth and metabolic outcome in adolescents born preterm (GROWMORE): follow-up protocol for the Newcastle Preterm Birth GRowth study (PTBGS).

scientific article

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report

scientific article published in March 2022

Hereditary hemochromatosis gene (HFE) variants are associated with birth weight and childhood leukemia risk

scientific article published in December 2009

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

scientific article published on 17 August 2021

How the Newcastle Thousand Families birth cohort study has contributed to the understanding of the impact of birth weight and early life socioeconomic position on disease in later life

scientific article published on 04 March 2012

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

scientific article published on 24 June 2019

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

scientific article

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

scientific article published on 29 June 2018

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

scientific article published on 07 January 2020

Impaired functional vitamin B6 status is associated with increased risk of lung cancer

scientific article published on 14 December 2017

Induction of Epigenetic Alterations by Dietary and Other Environmental Factors

scientific article published on January 1, 2010

Inflammation-related epigenetic risk and child and adolescent mental health: A prospective study from pregnancy to middle adolescence

scientific article published on 01 August 2018

Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women

scientific article

Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study

scientific article published on 26 June 2019

Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

Investigating causality in the association between DNA methylation and type 2 diabetes using bidirectional two-sample Mendelian randomisation

scientific article published in July 2023

Investigating the impact of cigarette smoking behaviours on DNA methylation patterns in adolescence

scientific article published on 01 January 2019

Is epidemiology ready for epigenetics? ⬇️

scientific article published on February 1, 2012

Is high vitamin B12 status a cause of lung cancer?

Juvenile idiopathic arthritis polygenic risk scores are associated with cardiovascular phenotypes in early adulthood: a phenome-wide association study

scientific article published on 19 November 2022

Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

Longitudinal analysis of DNA methylation associated with birth weight and gestational age.

scientific article published on 13 April 2015

Longitudinal analysis strategies for modelling epigenetic trajectories

scientific article published on 16 February 2018

Longitudinal epigenetic predictors of amygdala:hippocampus volume ratio

scientific article published on 8 May 2017

Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences

scientific article published on 04 February 2019

Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy

scientific article published in April 2004

Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot

scientific article

MELODI: Mining Enriched Literature Objects to Derive Intermediates

scientific article published on 12 January 2018

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

scientific article published on October 2017

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

scientific article published on 10 October 2019

Maternal adiposity--a determinant of perinatal and offspring outcomes?

scientific article published on 25 September 2012

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

scientific article

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

scientific article published on 07 January 2021

Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 07 November 2018

Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium

scientific article published on 22 February 2021

Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study

scientific article published on 27 October 2017

Maternal folate supply and sex influence gene-specific DNA methylation in the fetal gut.

scientific article

Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children.

scientific article

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study

scientific article published on 26 March 2019

Maternal smoking during pregnancy and autism: using causal inference methods in a birth cohort study

scientific article published on 29 November 2018

Meffil: efficient normalization and analysis of very large DNA methylation datasets

scientific article published on 21 June 2018

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

scientific article published in October 2017

Mendelian randomization: applications and limitations in epigenetic studies

scientific article published on 07 December 2015

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills

scientific article published in April 2022

Methods for Dealing With Missing Covariate Data in Epigenome-Wide Association Studies

scientific article published on 01 November 2019

Migration and DNA methylation: a comparison of methylation patterns in type 2 diabetes susceptibility genes between indians and europeans

scientific article published on 6 February 2013

Mitochondrial DNA Mutations in Individuals Occupationally Exposed to Ionizing Radiation

scientific article published in February 2006

Modelling pooling strategies for SARS-CoV-2 testing in a university setting

scientific article published on 30 March 2021

Moving from nature to nurture: a systematic review and meta-analysis of environmental factors associated with juvenile idiopathic arthritis

publication published on 01 February 2022

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

scientific article published on 13 December 2011

Neonatal DNA methylation and early-onset conduct problems: A genome-wide, prospective study

scientific article published on 09 June 2017

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

scientific article published on 14 February 2019

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

scientific article published on 8 June 2017

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey

scientific article published on 14 October 2008

Pathogenic mitochondrial DNA mutations are common in the general population

scientific article published on August 2008

Pathways between early-life adversity and adolescent self-harm: the mediating role of inflammation in the Avon Longitudinal Study of Parents and Children

scientific article published on 04 September 2019

People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population

scientific article published on 10 August 2011

Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer

scientific article

Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass

scientific article published on 21 December 2011

Pre-adolescence DNA methylation is associated with BMI status change from pre- to post-adolescence

scientific article published on 25 March 2021

Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood

scientific article published on 06 January 2021

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis

scientific article published on 31 May 2019

Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies

scientific article published on 5 November 2015

Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age.

scientific article

Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC).

scientific article

Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?

scientific article published on June 2012

Prenatal unhealthy diet, insulin-like growth factor 2 gene (IGF2) methylation, and attention deficit hyperactivity disorder symptoms in youth with early-onset conduct problems

scientific article published on 18 August 2016

Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema

article

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

article

Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.

scientific article published on 22 January 2018

RE: Prenatal smoke exposure, DNA methylation and a link between DRD1 and lung cancer

scientific article published on 01 August 2019

Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor

scientific article published on 28 February 2017

Role of DNA methylation in the relationship between glioma risk factors and glioma incidence: a two-step Mendelian randomization study

scientific article published on 21 April 2023

Role of obesity in smoking behaviour: Mendelian randomisation study in UK Biobank.

scientific article

SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts

scientific article published on 22 August 2018

Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study

scientific article published on 21 January 2019

Serum B vitamin levels and risk of lung cancer

scientific article published in June 2010

Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study

scientific article published on 27 July 2016

Sex differences in the association between infant feeding and blood cholesterol in later life: the Newcastle thousand families cohort study at age 49-51 years.

scientific article published on 29 May 2009

Sex discordance in asthma and wheeze prevalence in two longitudinal cohorts

scientific article

Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study

scientific article published on 8 October 2022

Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood

Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways

scientific article published on 20 February 2020

Smoking, Secondhand Smoke, and Cotinine Levels in a Subset of EPIC Cohort

Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth cohort

scientific article published on 01 February 2019

Statistical and integrative system-level analysis of DNA methylation data

scientific article

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease

scientific article published on 15 September 2018

Systematic identification of genetic influences on methylation across the human life course

scientific article published on 31 March 2016

The EWAS Catalog: a database of epigenome-wide association studies

scientific article published in 2022

The MR-Base platform supports systematic causal inference across the human phenome.

scientific article published on 30 May 2018

The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study

scientific article published in September 2017

The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings

scientific article published on 3 May 2017

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

scientific article published in May 2023

The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study

scientific article published on 04 August 2016

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

scientific article published on 01 April 2019

The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort.

scientific article published on 15 January 2017

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

scientific article published in December 2022

The influence of erythrocyte folate and serum vitamin B12 status on birth weight

scientific article published in May 2005

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study ⬇️

scientific article published on 03 January 2019

The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST).

scientific article published on 12 March 2018

The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities ⬇️

scientific article (publication date: 29 June 2012)

Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom

article

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

scientific journal article

Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data

scientific article published on 01 January 2019

Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease ⬇️

scientific article published on February 1, 2012

Use of Correct and Incorrect Methods of Accounting for Age in Studies of Epigenetic Accelerated Aging: Implications and Recommendations for Best Practices

scientific article published on 5 May 2023

Use of Mendelian andomization for dentifying isk actors for rain umors

scholarly article by Amy Elizabeth Howell et al published 2018 in Frontiers in Genetics

Using Openly Accessible Resources to Strengthen Causal Inference in Epigenetic Epidemiology of Neurodevelopment and Mental Health

scientific article published on 01 March 2019

Validation and characterisation of a DNA methylation alcohol biomarker across the life course

scientific article published on 27 November 2019

Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts

scientific article

Variation in DNA methylation of the oxytocin receptor gene predicts children's resilience to prenatal stress

scientific article

Vitamin B6 catabolism and lung cancer risk: results from the Lung Cancer Cohort Consortium (LC3)

scholarly article by H Zuo et al published 1 March 2019 in Annals of Oncology

What is it about boys?

scientific article published in February 2014

When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?

scientific article published in The Journal of the American Medical Association

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

scientific article published on 23 May 2017

Whole-genome sequence-based analysis of thyroid function.

scientific article

Paulina is supported by:

About Paulina

Help