List of works - Troy A Hornberger

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling.

scientific article

A deep analysis of the proteomic and phosphoproteomic alterations that occur in skeletal muscle after the onset of immobilization

scientific article published on 09 May 2021

A map of the phosphoproteomic alterations that occur after a bout of maximal-intensity contractions

scientific article

A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy

scientific article

A role for Raptor phosphorylation in the mechanical activation of mTOR signaling.

scientific article

Aging does not alter the mechanosensitivity of the p38, p70S6k, and JNK2 signaling pathways in skeletal muscle

scientific article published on 10 September 2004

COX-2 inhibitor reduces skeletal muscle hypertrophy in mice.

scientific article

Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome.

scientific article published on 3 June 2013

Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy

scientific article published on 11 April 2011

Evidence that mechanosensors with distinct biomechanical properties allow for specificity in mechanotransduction

scientific article published on July 2009

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

scientific article

Identifying the Structural Adaptations that Drive the Mechanical Load-Induced Growth of Skeletal Muscle: A Scoping Review

scientific article published on 09 July 2020

Imaging of protein synthesis with puromycin.

scientific article published on 23 March 2012

Inflammatory cells in rat skeletal muscle are elevated after electrically stimulated contractions

scientific article published on 01 November 2002

Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans

scientific article published on 01 February 2004

Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis.

scientific article published on 6 May 2009

Lipid domain-dependent regulation of single-cell wound repair

scientific article

Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration

scientific article

Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid ⬇️

scientific article published on October 15, 2012

Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.

scientific article published in April 2006

Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism

scientific article published on June 2004

Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle

scientific article published on 19 May 2011

Mechanotransduction and the regulation of protein synthesis in skeletal muscle.

scientific article published in May 2004

Muscle fiber type-dependent differences in the regulation of protein synthesis

scientific article

New roles for Smad signaling and phosphatidic acid in the regulation of skeletal muscle mass.

scientific article published on April 2014

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

scientific article

Phosphatidic acid enhances mTOR signaling and resistance exercise induced hypertrophy

scientific article

Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat.

scientific article published in February 2004

Prioritization of skeletal muscle growth for emergence from hibernation

scientific article

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

scientific article published on 23 July 2011

Regulation of mTOR by mechanically induced signaling events in skeletal muscle.

scientific article published on July 2006

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats

scientific article published on 01 July 2001

Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth

scientific article published on 01 October 2003

Skeletal muscle intermediate filaments form a stress-transmitting and stress-signaling network.

scientific article

Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo.

scientific article published on 03 September 2013

Soy-derived Phosphatidic Acid, Lysophosphatidic acid and Phosphatidylserine are sufficient to induce an increase in mTOR signaling.

scientific article published on 6 December 2013

The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting

scientific article published on 29 October 2013

The role of diacylglycerol kinase ζ and phosphatidic acid in the mechanical activation of mammalian target of rapamycin (mTOR) signaling and skeletal muscle hypertrophy

scientific article published on 03 December 2013

The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.

scientific article published on 26 May 2009

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

scholarly article

The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth

scientific article published on 26 September 2011

Translational control: implications for skeletal muscle hypertrophy.

scientific article

Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice

scientific article published on 25 July 2007

mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)

scientific article published on 31 August 2007

List of works by Troy A Hornberger

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling.

A deep analysis of the proteomic and phosphoproteomic alterations that occur in skeletal muscle after the onset of immobilization

A map of the phosphoproteomic alterations that occur after a bout of maximal-intensity contractions

A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy

A role for Raptor phosphorylation in the mechanical activation of mTOR signaling.

Aging does not alter the mechanosensitivity of the p38, p70S6k, and JNK2 signaling pathways in skeletal muscle

COX-2 inhibitor reduces skeletal muscle hypertrophy in mice.

Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome.

Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy

Evidence that mechanosensors with distinct biomechanical properties allow for specificity in mechanotransduction

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

Identifying the Structural Adaptations that Drive the Mechanical Load-Induced Growth of Skeletal Muscle: A Scoping Review

Imaging of protein synthesis with puromycin.

Inflammatory cells in rat skeletal muscle are elevated after electrically stimulated contractions

Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans

Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis.

Lipid domain-dependent regulation of single-cell wound repair

Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration

Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid ⬇️

Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.

Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism

Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle

Mechanotransduction and the regulation of protein synthesis in skeletal muscle.

Muscle fiber type-dependent differences in the regulation of protein synthesis

New roles for Smad signaling and phosphatidic acid in the regulation of skeletal muscle mass.

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

Phosphatidic acid enhances mTOR signaling and resistance exercise induced hypertrophy

Physiological hypertrophy of the FHL muscle following 8 weeks of progressive resistance exercise in the rat.

Prioritization of skeletal muscle growth for emergence from hibernation

Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass

Regulation of mTOR by mechanically induced signaling events in skeletal muscle.

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats

Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth

Skeletal muscle intermediate filaments form a stress-transmitting and stress-signaling network.

Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo.

Soy-derived Phosphatidic Acid, Lysophosphatidic acid and Phosphatidylserine are sufficient to induce an increase in mTOR signaling.

The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting

The role of diacylglycerol kinase ζ and phosphatidic acid in the mechanical activation of mammalian target of rapamycin (mTOR) signaling and skeletal muscle hypertrophy

The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth

Translational control: implications for skeletal muscle hypertrophy.

Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice

mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)