List of works - Łukasz Berlicki

1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors

scientific article published on 14 August 2016

A computationally designed β-amino acid-containing miniprotein

scientific article published in 2021

A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases

scientific article published on 9 April 2016

Aminophosphinates against Helicobacter pylori ureolysis-Biochemical and whole-cell inhibition characteristics.

scientific article

An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.

scientific article

Analysis of pD-dependent complexation of N-benzyloxycarbonylaminophosphonic acids by alpha-cyclodextrin. Enantiodifferentiation of phosphonic acid pKa values.

scientific article

Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.

scientific article

Bis(aminomethyl)phosphinic Acid, a Highly Promising Scaffold for the Development of Bacterial Urease Inhibitors.

scientific article

Bisphosphonic acids and related compounds as inhibitors of nucleotide- and polyphosphate-processing enzymes: A PPK1 and PPK2 case study.

scientific article

Bisphosphonic acids as effective inhibitors of Mycobacterium tuberculosis glutamine synthetase

scientific article published on 03 August 2015

Catechol-based inhibitors of bacterial urease

scientific article published on 27 February 2019

Chiral discrimination of ethyl and phenyl N-benzyloxycarbonylaminophosphonates by cyclodextrins

Cinchona alkaloids as privileged chiral solvating agents for the enantiodiscrimination of N-protected aminoalkanephosphonates—a comparative NMR study

Computer-Aided Analysis and Design of Phosphonic and Phosphinic Enzyme Inhibitors as Potential Drugs and Agrochemicals

Computer-aided analysis of the interactions of glutamine synthetase with its inhibitors

scientific article published on 28 February 2006

Computer-aided optimization of phosphinic inhibitors of bacterial ureases.

scientific article published on August 2010

Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting

scientific article published on 12 January 2017

Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting.

scientific article published on 12 January 2017

Controlling the conformational stability of coiled-coil peptides with a single stereogenic center of a peripheral β-amino acid residue

scientific article

Covalent Inhibition of Bacterial Urease by Bifunctional Catechol-Based Phosphonates and Phosphinates

scientific article published on 28 December 2020

Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction

scientific article published on 20 August 2020

Cyclodextrins as NMR probes in the study of the enantiomeric compositions of N-benzyloxycarbonylamino-phosphonic and phosphinic acids

article

Design, synthesis, and activity of analogues of phosphinothricin as inhibitors of glutamine synthetase

scientific article

Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases

scientific article

Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity.

scientific article published on 19 July 2017

Effectiveness and mode of action of phosphonate inhibitors of plant glutamine synthetase

scientific article published in January 2010

Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis

scientific article published on 09 November 2006

Enantiodifferentiation of alpha-hydroxyalkanephosphonic acids in 31P NMR with application of alpha-cyclodextrin as chiral discriminating agent

scientific article published in January 2010

Enantiodifferentiation of aminophosphonic and aminophosphinic acids with α- and β-cyclodextrins

Frontispiece: Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics

scientific article published on 17 July 2018

Herbicidal pyridyl derivatives of aminomethylene-bisphosphonic acid inhibit plant glutamine synthetase

scientific article

Hierarchical approach for the rational construction of helix-containing nanofibrils using α,β-peptides

scientific article published in 2021

Inhibitors of glutamine synthetase and their potential application in medicine

scientific article published on August 2008

Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates

N-substituted aminomethanephosphonic and aminomethane-P-methylphosphinic acids as inhibitors of ureases.

scientific article

Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles

scientific article

Nuclear immunophilin FKBP39 from Drosophila melanogaster drives spontaneous liquid-liquid phase separation

scientific article published on 29 June 2020

Organophosphorus Supramolecular Chemistry Part 1. Receptors for Organophosphorus Compounds

Organophosphorus Supramolecular Chemistry. Part 2. Organophosphorus Receptors

Peptide-based inhibitors of protein-protein interactions.

scientific article

Peptides containing β-amino acid patterns: challenges and successes in medicinal chemistry

scientific article published on 24 September 2014

Phosphinothricin analogues as inhibitors of plant glutamine synthetases

scientific article published in February 2006

Phosphorylation as a method of tuning the enantiodiscrimination potency of quinine-An NMR study

scientific article published on 17 February 2012

Phytotoxicity of aminobisphosphonates targeting both δ1 -pyrroline-5-carboxylate reductase and glutamine synthetase

scientific article

Plant P5C reductase as a new target for aminomethylenebisphosphonates.

scientific article published on 3 May 2007

Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling.

scientific article published on 12 February 2017

Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry

scientific article published on 05 August 2011

Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane and cis-cyclopentane β-amino acids shifts selectivity toward the Y(4) receptor.

scientific article published on 25 October 2013

Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

scientific article

Structural exploration of cinnamate-based phosphonic acids as inhibitors of bacterial ureases

scientific article published on 02 October 2018

Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.

scientific article

Synthesis and evaluation of effective inhibitors of plant δ1-pyrroline-5-carboxylate reductase

scientific article

Systematic 'foldamerization' of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans- or cis-2-aminocyclopentanecarboxylic acid residues

scientific article published on 11 September 2020

Tailoring the structure of aminobisphosphonates to target plant P5C reductase

scientific article published on 10 April 2008

The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design

scientific article

The use of molecular modelling for comparison of three possible modes of action of herbicidally active derivatives of aminomethylenebisphosphonic acid

scientific article published in 2002

Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides

scientific article published on 24 May 2013

Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid

scholarly article by Łukasz Berlicki et al published 26 January 2012 in Angewandte Chemie International Edition

Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review ⬇️

scientific article published on 04 April 2011

Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy

scientific article published on 25 August 2015

Δ1-pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

scientific article published on 09 July 2011

List of works by Łukasz Berlicki

1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors

A computationally designed β-amino acid-containing miniprotein

A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases

Aminophosphinates against Helicobacter pylori ureolysis-Biochemical and whole-cell inhibition characteristics.

An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.

Analysis of pD-dependent complexation of N-benzyloxycarbonylaminophosphonic acids by alpha-cyclodextrin. Enantiodifferentiation of phosphonic acid pKa values.

Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.

Bis(aminomethyl)phosphinic Acid, a Highly Promising Scaffold for the Development of Bacterial Urease Inhibitors.

Bisphosphonic acids and related compounds as inhibitors of nucleotide- and polyphosphate-processing enzymes: A PPK1 and PPK2 case study.

Bisphosphonic acids as effective inhibitors of Mycobacterium tuberculosis glutamine synthetase

Catechol-based inhibitors of bacterial urease

Chiral discrimination of ethyl and phenyl N-benzyloxycarbonylaminophosphonates by cyclodextrins

Cinchona alkaloids as privileged chiral solvating agents for the enantiodiscrimination of N-protected aminoalkanephosphonates—a comparative NMR study

Computer-Aided Analysis and Design of Phosphonic and Phosphinic Enzyme Inhibitors as Potential Drugs and Agrochemicals

Computer-aided analysis of the interactions of glutamine synthetase with its inhibitors

Computer-aided optimization of phosphinic inhibitors of bacterial ureases.

Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting

Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting.

Controlling the conformational stability of coiled-coil peptides with a single stereogenic center of a peripheral β-amino acid residue

Covalent Inhibition of Bacterial Urease by Bifunctional Catechol-Based Phosphonates and Phosphinates

Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction

Cyclodextrins as NMR probes in the study of the enantiomeric compositions of N-benzyloxycarbonylamino-phosphonic and phosphinic acids

Design, synthesis, and activity of analogues of phosphinothricin as inhibitors of glutamine synthetase

Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases

Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity.

Effectiveness and mode of action of phosphonate inhibitors of plant glutamine synthetase

Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis

Enantiodifferentiation of alpha-hydroxyalkanephosphonic acids in 31P NMR with application of alpha-cyclodextrin as chiral discriminating agent

Enantiodifferentiation of aminophosphonic and aminophosphinic acids with α- and β-cyclodextrins

Frontispiece: Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics

Herbicidal pyridyl derivatives of aminomethylene-bisphosphonic acid inhibit plant glutamine synthetase

Hierarchical approach for the rational construction of helix-containing nanofibrils using α,β-peptides

Inhibitors of glutamine synthetase and their potential application in medicine

Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates

N-substituted aminomethanephosphonic and aminomethane-P-methylphosphinic acids as inhibitors of ureases.

Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles

Nuclear immunophilin FKBP39 from Drosophila melanogaster drives spontaneous liquid-liquid phase separation

Organophosphorus Supramolecular Chemistry Part 1. Receptors for Organophosphorus Compounds

Organophosphorus Supramolecular Chemistry. Part 2. Organophosphorus Receptors

Peptide-based inhibitors of protein-protein interactions.

Peptides containing β-amino acid patterns: challenges and successes in medicinal chemistry

Phosphinothricin analogues as inhibitors of plant glutamine synthetases

Phosphorylation as a method of tuning the enantiodiscrimination potency of quinine-An NMR study

Phytotoxicity of aminobisphosphonates targeting both δ1 -pyrroline-5-carboxylate reductase and glutamine synthetase

Plant P5C reductase as a new target for aminomethylenebisphosphonates.

Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling.

Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry

Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane and cis-cyclopentane β-amino acids shifts selectivity toward the Y(4) receptor.

Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

Structural exploration of cinnamate-based phosphonic acids as inhibitors of bacterial ureases

Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.

Synthesis and evaluation of effective inhibitors of plant δ1-pyrroline-5-carboxylate reductase

Systematic 'foldamerization' of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans- or cis-2-aminocyclopentanecarboxylic acid residues

Tailoring the structure of aminobisphosphonates to target plant P5C reductase

The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design

The use of molecular modelling for comparison of three possible modes of action of herbicidally active derivatives of aminomethylenebisphosphonic acid

Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides

Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid

Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review ⬇️

Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy

Δ1-pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo