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List of works by Vincent W. Keng

A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.

scientific article

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

scientific article published on 22 February 2009

A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver

scientific article

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance

scientific article published on 27 March 2013

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice

scientific article

Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.

scientific article

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity.

scientific article

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

scientific article published on 18 December 2012

Conditional Inactivation of and in Schwann Cells Results in Abnormal Neuromuscular Junction Maturation

scientific article published on 09 January 2019

Efficient transposition of Tol2 in the mouse germline

scientific article published on 05 October 2009

Expression of Hex mRNA in early murine postimplantation embryo development

scientific article published on April 1998

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

scientific article published on 19 May 2013

Generating mutant rats using the Sleeping Beauty transposon system

scientific article published on 4 May 2009

Genomic organization and promoter analysis of a mouse homeobox gene, Hex.

scientific article

Germline mutagenesis mediated by Sleeping Beauty transposon system in mice

scientific article published on January 2007

HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism

scientific article published on 11 April 2019

Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage

scientific journal article

Identification and characterization of the hematopoietic cell-specific enhancer-like element of the mouse hex gene

scientific article published on February 2004

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis

scientific article

Identification of the transactivating region of the homeodomain protein, hex.

scientific article published in February 2004

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.

scientific article published on 16 February 2016

Insulin stimulates expression of the pyruvate kinase M gene in 3T3-L1 adipocytes

scientific article published on June 2003

Liver-Specific Delivery of Sleeping Beauty Transposon System by Hydrodynamic Injection for Cancer Gene Validation

scientific article published on 01 January 2019

Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system.

scientific article

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

scientific article published on 26 February 2013

Mouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studies

scientific article

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.

scientific article

Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system

scientific article published on 01 October 2005

Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits

scientific article published on 15 April 2007

Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy

scientific article published on 21 May 2019

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

scientific article

Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.

scientific article published on 9 October 2017

Sleeping beauty transposase has an affinity for heterochromatin conformation

scientific article published on 18 December 2006

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth

scientific article published on August 2006

Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation

scientific article published on 18 December 2018

Sp family members stimulate transcription of the hex gene via interactions with GC boxes

scientific article

Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor

article published in 2018

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma.

scientific article published in September 2017

Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: implication for retrotransposon-mediated genome evolution.

scientific article published on 2 May 2008

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

scientific article

Transposon-tagged mutagenesis in the rat.

scientific article published on 14 January 2007

Why men are at higher risk for hepatocellular carcinoma?

scientific article

cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the protein

scientific journal article

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