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List of works by Marieke Griffioen

A mechanistic rationale for combining alemtuzumab and rituximab in the treatment of ALL.

scientific article published on 15 September 2010

A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR.

scientific article

ARTISAN PCR: rapid identification of full-length immunoglobulin rearrangements without primer binding bias.

scientific article published on 15 June 2016

Analysis of T-cell responses in metastatic melanoma patients vaccinated with dendritic cells pulsed with tumor lysates

scientific article published on 3 March 2004

Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets

scientific article

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

scientific article published on 25 March 2019

Both permissive and nonpermissive HLA-DPB1 mismatches can induce polyclonal HLA-DPB1 specific immune responses in vivo and in vitro

article

C-myc represses transiently transfected HLA class I promoter sequences not locus-specifically

scientific article published on 01 July 1995

CD4 Donor Lymphocyte Infusion Can Cause Conversion of Chimerism Without GVHD by Inducing Immune Responses Targeting Minor Histocompatibility Antigens in HLA Class II

article

CD4+ Th2 cell recognition of HLA-DR-restricted epitopes derived from CAMEL: a tumor antigen translated in an alternative open reading frame

scientific article published on February 2003

Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY

scientific article published on 17 June 2019

Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

scientific article published on 03 March 2020

Detection and functional analysis of CD8+ T cells specific for PRAME: a target for T-cell therapy

scientific article published in May 2006

Detection and quantification of CD8+ T cells specific for HLA-A*0201-binding melanoma and viral peptides by the IFN-?-elispot assay

scientific article published on 01 August 2001

Development of a coordinated allo T cell and auto B cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation

scientific article published on 04 October 2013

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

scientific article published on 11 March 2020

Donor T cells administered over HLA class II barriers mediate antitumor immunity without broad off-target toxicity in a NOD/scid mouse model of acute leukemia.

scientific article published on 13 March 2013

Durable remission of renal cell carcinoma in conjuncture with graft versus host disease following allogeneic stem cell transplantation and donor lymphocyte infusion: rule or exception?

scientific article published on 15 January 2014

Efficiency and mechanism of antigen-specific CD8+ T-cell activation using synthetic long peptides

scientific article published in February 2012

Endogenous HLA class II epitopes that are immunogenic in vivo show distinct behavior toward HLA-DM and its natural inhibitor HLA-DO.

scientific article published on 13 August 2012

Establishment and characterization of an uveal-melanoma cell line.

scientific article published on July 1995

Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells

scientific article published on 12 November 2020

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

scientific article

Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation

scientific article published on 15 February 2022

HLA class II upregulation during viral infection leads to HLA-DP-directed graft-versus-host disease after CD4+ donor lymphocyte infusion.

scientific article published on 18 June 2013

HLA-B down-regulation in human melanoma is mediated by sequences located downstream of the transcription-initiation site

scientific article published on 01 February 1999

HLA-B locus-specific downregulation in human melanoma requires enhancer A as well as a sequence element located downstream of the transcription initiation site

scientific article published on 01 November 2000

HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia

scientific article published on 17 April 2008

HLA-DPB1 Mismatching Results in the Generation of a Full Repertoire of HLA-DPB1-Specific CD4+ T Cell Responses Showing Immunogenicity of all HLA-DPB1 Alleles

article

HLA-class II disparity is necessary for effective T cell mediated Graft-versus-Leukemia effects in NOD/scid mice engrafted with human acute lymphoblastic leukemia.

scientific article published on 17 September 2012

High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning

scientific article published on 9 November 2010

Human allo-reactive CD4+ T cells as strong mediators of anti-tumor immunity in NOD/scid mice engrafted with human acute lymphoblastic leukemia

scientific article published on 23 August 2011

Human leukocyte antigen-DO regulates surface presentation of human leukocyte antigen class II-restricted antigens on B cell malignancies

scientific article published on 14 February 2014

Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity

scientific article published on 25 August 2009

Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity

scientific article

Identification of Biological Relevant Minor Histocompatibility Antigens within the B-lymphocyte-Derived HLA-Ligandome Using a Reverse Immunology Approach.

scientific article

Identification of multiple HLA-DR-restricted epitopes of the tumor-associated antigen CAMEL by CD4+ Th1/Th2 lymphocytes

scientific article published on April 2004

Identification of phosphatidylinositol 4-kinase type II beta as HLA class II-restricted target in graft versus leukemia reactivity

scientific article

Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

scientific article published on 25 March 2019

Induction of CAMEL/NY-ESO-ORF2-specific CD8+ T cells upon stimulation with dendritic cells infected with a modified Ad5 vector expressing a chimeric Ad5/35 fiber

scientific article published on March 2004

Influence of increased c-Myc expression on the growth characteristics of human melanoma

scientific article published on March 1999

Integrated Whole Genome and Transcriptome Analysis Identified a Therapeutic Minor Histocompatibility Antigen in a Splice Variant of ITGB2.

scientific article published on 10 March 2016

Integrated whole genome and transcriptome analysis identified a therapeutic minor histocompatibility antigen encoded by an alternative ITGB2 transcript.

scientific article published on 4 November 2015

Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice

scientific article

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

scientific article published on 11 June 2015

Loss of the GPI-anchor in B-lymphoblastic leukemia by epigenetic downregulation of PIGH expression

scientific article published on 25 November 2018

Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies.

scientific article

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia

scientific article published on 14 January 2019

Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles

scientific article published on 17 August 2018

Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens

scientific article published on 17 April 2020

PRAME-Specific Allo-HLA-Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer

article

Patient HLA-DP-specific CD4+ T cells from HLA-DPB1-mismatched donor lymphocyte infusion can induce graft-versus-leukemia reactivity in the presence or absence of graft-versus-host disease

scientific article

Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM

scientific article published on 06 September 2020

Repression of the minimal HLA-B promoter by c-myc and p53 occurs through independent mechanisms

scientific article published on September 1998

Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy

scientific article

Role of the interferon-stimulated response element in HLA-B downregulation in human melanoma cell lines

scientific article published on 01 April 1999

Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response

scientific article published on 9 January 2017

T Cells Specific for an Unconventional Natural Antigen Fail to Recognize Leukemic Cells

scientific article published on 19 March 2019

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

scientific article published on 06 December 2021

T-cell receptor gene transfer for treatment of leukemia.

scientific article published on January 2008

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1.

scientific article published on 4 January 2017

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

scientific article

The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses

scientific article published on 25 November 2020

The Value of Online Algorithms to Predict T-Cell Ligands Created by Genetic Variants

scientific article

Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1.

scientific article published on October 2012

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