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List of works by Jack W. Singer

A phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors

scientific article published on 06 August 2008

An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome

scientific article

Anthracycline cardiotoxicity: clinical and pathologic outcomes assessed by radionuclide ejection fraction

scientific article published on 01 September 1980

Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib

scientific article published on November 2006

Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma

scientific article published on December 2003

Arsenic trioxide and thalidomide combination produces multi-lineage hematological responses in myelodysplastic syndromes patients, particularly in those with high pre-therapy EVI1 expression.

scientific article

Bone marrow transplantation in a patient with myelodysplasia associated with diffuse eosinophilic fasciitis

scientific article published in January 1987

Chronic lymphocytic leukaemia: Clonal origin in a committed B-lymphocyte progenitor ⬇️

scientific article published on August 26, 1978

Chronic lymphocytosis with neutropenia: evidence for a novel, abnormal T-cell population associated with antibody-mediated neutrophil destruction

scientific article published on 01 April 1983

Comparative phenotypic profiling of the JAK2 inhibitors ruxolitinib, fedratinib, momelotinib, and pacritinib reveals distinct mechanistic signatures

scientific article published on 27 September 2019

Comparison of pixantrone-based regimen (CPOP-R) with doxorubicin-based therapy (CHOP-R) for treatment of diffuse large B-cell lymphoma

scientific article published on 14 August 2013

Correlation between cytogenetic and molecular findings in human chronic myelogenous leukemia lines EM-2 and EM-3.

scientific article published on April 1987

Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta

scientific article

Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man.

scientific article

Effect of GM-CSF on circulating granulocyte-monocyte progenitors in autologous bone marrow transplantation

scientific article published in December 1989

Evidence for a stem cell common to hematopoiesis and its in vitro microenvironment: studies of patients with clonal hematopoietic neoplasia

scientific article published in January 1984

Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosis

scientific article

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

scientific article published on July 2005

Lisofylline suppresses ex vivo release by murine spleen cells of hematopoietic inhibitors induced by cancer chemotherapeutic agents

scientific article published on 01 August 2000

Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival

scientific article published on 01 October 2006

Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.

scientific article published on April 2005

Non-small cell lung cancer: does estrogen affect outcome?

scientific article published on 01 January 2007

Paclitaxel poliglumex (XYOTAX, CT-2103): a macromolecular taxane.

scientific article

Paclitaxel poliglumex (XYOTAX; CT-2103): an intracellularly targeted taxane.

scientific article

Phase I/II study of pixantrone in combination with cyclophosphamide, vincristine, and prednisone in patients with relapsed aggressive non-Hodgkin lymphoma

scientific article published on 01 April 2011

Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naïve advanced non-small cell lung cancer.

scientific article published in June 2008

Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice.

scientific article

Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells

scientific article

Pixantrone dimaleate in combination with fludarabine, dexamethasone, and rituximab in patients with relapsed or refractory indolent non-Hodgkin lymphoma: phase 1 study with a dose-expansion cohort

scientific article published on 16 June 2011

Pixantrone dimaleate versus other chemotherapeutic agents as a single-agent salvage treatment in patients with relapsed or refractory aggressive non-Hodgkin lymphoma: a phase 3, multicentre, open-label, randomised trial

scientific article

Preferential radiosensitization of G1 checkpoint-deficient cells by methylxanthines.

scientific article

Prevalence of clinically relevant bacteremia after upper gastrointestinal endoscopy in bone marrow transplant recipients

scientific article published on 01 August 1990

Procoagulant inhibitory properties of paclitaxel poliglumex.

scientific article

Radiopharmaceutical reimbursement rates

scientific article published on 01 June 2008

Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naïve advanced non-small cell lung cancer

scientific article published in July 2008

Responsiveness of the in vitro hematopoietic microenvironment to platelet-derived growth factor

scientific article published in January 1985

Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: prognostic factors and treatment selection based on two large randomized clinical trials

scientific article

Substrate specificity of lysophosphatidic acid acyltransferase beta -- evidence from membrane and whole cell assays

scientific article published on 20 December 2005

Synthesis and in vivo antitumor activity of poly(l-glutamic acid) conjugates of 20S-camptothecin

scientific article

Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-beta

scientific article published on May 2004

The Use of Genetic Markers in Studies of Myeloid Neoplasia

scientific article

The novel anthracenedione, pixantrone, lacks redox activity and inhibits doxorubicinol formation in human myocardium: insight to explain the cardiac safety of pixantrone in doxorubicin-treated patients.

scientific article published on 28 November 2012

The use of recombinant human granulocyte macrophage colony-stimulating factor in autologous and allogeneic bone marrow transplantation

scientific article

Tolerability and toxicological profile of pixantrone (Pixuvri®) in juvenile mice. Comparative study with doxorubicin

scientific article published on 03 March 2014

Treatment of chronic granulocytic leukaemia in chronic phase by allogeneic marrow transplantation

scientific article published on 01 September 1982

Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo

scientific article published in July 2001

rhGM-CSF after allogeneic bone marrow transplantation from unrelated donors: a pilot study of cyclosporine and prednisone as graft-versus-host disease prophylaxis

scientific article published on June 1993

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