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List of works by James D. West

Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule.

scientific article

Aromatic Residues at the Dimer-Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function

scientific article published on 11 February 2019

Bifunctional electrophiles cross-link thioredoxins with redox relay partners in cells.

scientific article published on 4 March 2013

Endogenous reactive intermediates as modulators of cell signaling and cell death.

scientific article

Enhanced Toxicity of the Protein Cross-Linkers Divinyl Sulfone and Diethyl Acetylenedicarboxylate in Comparison to Related Monofunctional Electrophiles ⬇️

scientific article published on August 8, 2011

Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation

scientific article published in 2004

Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1.

scientific article published on 9 February 2005

Piecing Together How Peroxiredoxins Maintain Genomic Stability

article by James D. West et al published 28 November 2018 in Antioxidants (Basel, Switzerland)

Pronounced toxicity differences between homobifunctional protein cross-linkers and analogous monofunctional electrophiles

scientific article

Redox requirements for ubiquitin-like urmylation of Ahp1, a 2-Cys peroxiredoxin from yeast

scientific article published on 22 January 2020

Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise ⬇️

scientific article published on July 31, 2012

Structure-activity comparison of the cytotoxic properties of diethyl maleate and related molecules: identification of diethyl acetylenedicarboxylate as a thiol cross-linking agent.

scientific article published on 24 November 2010

The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds.

scientific article

Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker.

scientific article published on 2 November 2016

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