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List of works by María J. Vicent

A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury

scientific article

A polymeric nanomedicine diminishes inflammatory events in renal tubular cells

scientific article

Anticancer Activity Driven by Drug Linker Modification in a Polyglutamic Acid-Based Combination-Drug Conjugate

Biocompatibility Reduces Inflammation-Induced Apoptosis in Mesothelial Cells Exposed to Peritoneal Dialysis Fluid

scientific article published on 01 January 2015

Capturing "Extraordinary" Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design

scientific article published on 23 August 2017

Characterization of triple-negative breast cancer preclinical models provides functional evidence of metastatic progression

scientific article published on 02 April 2019

Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines

scientific article published on 20 August 2009

Combined polymer-curcumin conjugate and ependymal progenitor/stem cell treatment enhances spinal cord injury functional recovery.

scientific article

Comparative profiling of whole-cell and exosome samples reveals protein signatures that stratify breast cancer subtypes

scientific article published on 22 August 2024

Demonstrating the importance of polymer-conjugate conformation in solution on its therapeutic output: Diethylstilbestrol (DES)-polyacetals as prostate cancer treatment

scientific article published on 31 December 2011

Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery

scientific article published on 05 April 2017

Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery

scientific article published in October 2017

Discovery of inhibitors of protein-protein interactions from combinatorial libraries

scientific article

Do HPMA copolymer conjugates have a future as clinically useful nanomedicines? A critical overview of current status and future opportunities.

scientific article published on 11 December 2009

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

scientific article published on 07 January 2019

Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate

scientific article published on 06 February 2020

Envisioning the future of polymer therapeutics for brain disorders

scientific article published on 14 June 2018

Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders

scientific article published in 2019

HIF-1α inhibition by diethylstilbestrol and its polyacetal conjugate in hypoxic prostate tumour cells: insights from NMR metabolomics.

scientific article published on 18 August 2017

HPMA copolymer-aminoglutethimide conjugates inhibit aromatase in MCF-7 cell lines

scientific article published on September 2005

Hemodynamic effects of HPMA copolymer based doxorubicin conjugate: A randomized controlled and comparative spectral study in conscious rats.

scientific article published on 18 January 2017

Identification of miR-187 and miR-182 as biomarkers of early diagnosis and prognosis in patients with prostate cancer treated with radical prostatectomy.

scientific article

Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel

scientific article published on 04 March 2011

Integrin-targeted nano-sized polymeric systems for paclitaxel conjugation: a comparative study.

scientific article published on 24 July 2017

Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells

scientific article published on 14 October 2006

Metabolomics facilitates the discrimination of the specific anti-cancer effects of free- and polymer-conjugated doxorubicin in breast cancer models.

scientific article published on 8 February 2018

MiR-187 Targets the Androgen-Regulated Gene ALDH1A3 in Prostate Cancer.

scientific article published on 13 May 2015

Modulating angiogenesis with integrin-targeted nanomedicines.

scientific article

Modulation of cellular apoptosis with apoptotic protease-activating factor 1 (Apaf-1) inhibitors

scientific journal article

Molecular platforms for targeted drug delivery

scientific article published on 09 April 2019

Molecules that modulate Apaf-1 activity

scientific article published on 22 January 2010

Nanoconjugates as intracorporeal neutralizers of bacterial endotoxins.

scientific article published on 30 October 2009

Near-Infrared Activatable Phthalocyanine–Poly-L-Glutamic Acid Conjugate: Enhanced in Vivo Safety and Antitumor Efficacy toward an Effective Photodynamic Cancer Therapy

scientific article published on 29 May 2018

Near-infrared activatable phthalocyanine-poly-L-glutamic acid conjugate: increased cellular uptake and light-dark toxicity ratio toward an effective photodynamic cancer therapy.

scientific article published on 16 February 2017

New CSPs based on peptidomimetics: efficient chiral selectors in enantioselective separations

New supported beta-amino alcohols as efficient catalysts for the enantioselective addition of diethylzinc to benzaldehyde under flow conditions.

scientific article published in October 2002

P(HPMA)-block-P(LA) copolymers in paclitaxel formulations: Polylactide stereochemistry controls micellization, cellular uptake kinetics, intracellular localization and drug efficiency

scientific article published in October 2012

Poly-L-glutamic acid (PGA) aided inhibitors of apoptotic protease activating factor 1 (Apaf-1): an antiapoptotic polymeric nanomedicine.

scientific article published on June 2006

Polyacetal-Based Combination Therapy for the Treatment of Prostate Cancer

article

Polyacetal-stilbene conjugates — The first examples of polymer therapeutics for the inhibition of HIF-1 in the treatment of solid tumours

article

Polymer Therapeutics as Nano-Sized Medicines for Tissue Regeneration and Repair

Polymer Therapeutics: Biomarkers and New Approaches for Personalized Cancer Treatment

scientific article published on 23 January 2018

Polymer conjugates as therapeutics: future trends, challenges and opportunities

scientific article published on 01 May 2008

Polymer masked-unmasked protein therapy. 1. Bioresponsive dextrin-trypsin and -melanocyte stimulating hormone conjugates designed for alpha-amylase activation

scientific article published on 19 March 2008

Polymer therapeutics designed for a combination therapy of hormone-dependent cancer

scientific article

Polymer therapeutics-prospects for 21st century: The end of the beginning ⬇️

scientific article published on 05 September 2012

Polymer therapeutics: Clinical applications and challenges for development

article

Polymer-doxycycline conjugates as fibril disrupters: an approach towards the treatment of a rare amyloidotic disease.

scientific article published on 4 December 2014

Polymer-drug conjugates: current status and future trends

scientific article published on January 2008

Polymer-drug conjugates: towards a novel approach for the treatment of endrocine-related cancer.

scientific article

Polypeptide-Based Conjugates as Therapeutics: Opportunities and Challenges.

scientific article

Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis

scientific article published on 14 December 2019

Preclinical safety assessments of nano-sized constructs on cardiovascular system toxicity: A case for telemetry.

scientific article published on 6 February 2017

Professor Ruth Duncan: a pioneer in the field of polymer therapeutics

scientific article

Reduction sensitive Poly(l-glutamic acid) (PGA)-protein conjugates designed for polymer masked-unmasked protein therapy

scientific article

Relevance of folic acid/polymer ratio in targeted PEG-epirubicin conjugates

scientific article published on 2 June 2010

Relevant Physicochemical Descriptors of "Soft Nanomedicines" to Bypass Biological Barriers.

scientific article published on 16 December 2015

Smart branched polymer drug conjugates as nano-sized drug delivery systems

scientific article published on 12 August 2015

Synthesis and in vitro evaluation of defined HPMA folate conjugates: influence of aggregation on folate receptor (FR) mediated cellular uptake

scientific article published on September 2010

Synthesis, Characterization and Preliminary Biological Evaluation of P(HPMA)-b-P(LLA) Copolymers: A New Type of Functional Biocompatible Block Copolymer

scientific article published on 9 June 2010

Targeting a rare amyloidotic disease through rationally designed polymer conjugates.

scientific article published on 31 January 2014

Total synthesis and preliminary biological evaluation of cis-solamin isomers

scientific article published on May 2004

Triblock Copolymer Nanovesicles for pH-Responsive Targeted Delivery and Controlled Release of siRNA to Cancer Cells.

scientific article published on 2 June 2015

Tumor microenvironment-targeted poly-L-glutamic acid-based combination conjugate for enhanced triple negative breast cancer treatment

scientific article published on 18 September 2018

Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I.

scientific article published on 16 December 2016

Using small-angle neutron scattering to study the solution conformation of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates

scientific article

Well-Defined Star-Shaped Polyglutamates with Improved Pharmacokinetic Profiles As Excellent Candidates for Biomedical Applications.

scientific article published on 10 September 2015

pH-Responsive Polyacetal-Protein Conjugates Designed for Polymer Masked-Unmasked Protein Therapy (PUMPT).

scientific article published on 6 December 2017

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