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List of works by Graham S. Baldwin

A kinetic and structural comparison of chorismate mutase/prephenate dehydratase from mutant strains of Escherichia coli K 12 defective in the PheA gene

scientific article published on 01 October 1981

A new role for an old hormone: Is gastrin a cofactor for dietary metal ion uptake? ⬇️

scientific article published on May 1, 1992

A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin.

scientific article published on 6 October 2003

A spectroscopic study of metal ion and ligand binding to beta-lactamase II.

scientific article published in November 1980

A synthetic peptide containing the autophosphorylation site of the transforming protein of Harvey sarcoma virus is phosphorylated by the EGF-stimulated tyrosine kinase

scientific article published in March 1983

Absence of common trifunctional protein mutation in patients with Alpers disease

scientific article published on 01 November 1997

Activation of Src family tyrosine kinases by ferric ions

scientific article

Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells

scientific article published on April 2003

Amino acid sequences of soluble tryptic peptides of chorismate mutase/prephenate dehydratase from Escherichia coli K12.

scientific article published on August 1979

Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein.

scientific article published on August 1994

Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer

scientific article published on 07 March 2019

Binding of a valproate metabolite to the trifunctional protein of fatty acid oxidation

scientific article published on 01 April 1996

Binding of gastrin to gastric transferrin

scientific article published on 01 September 1986

Binding of pepsinogen to the 78 kDa gastrin binding protein

scientific article published on 01 June 1999

Binding of progastrin fragments to the 78 kDa gastrin-binding protein

scientific article published on 01 February 1995

Binding sites for progastrin-derived peptides in colonic crypts.

scientific article

Biological activity and ferric ion binding of fragments of glycine-extended gastrin.

scientific article published on September 2004

Biologically active recombinant human progastrin(6-80) contains a tightly bound calcium ion.

scientific article

Bismuth ions inhibit the biological activity of non-amidated gastrins in vivo.

scientific article published on 8 December 2011

Blockade of long chain fatty acid oxidation by non-steroidal anti-inflammatory drugs may contribute to inhibition of proliferation of human colorectal carcinoma cell lines

scientific article published on 01 February 1998

C-terminal fragments of the gastrin-releasing peptide precursor stimulate cell proliferation via a novel receptor.

scientific article published on 22 November 2006

CCK receptors and cancer.

scientific article published on January 2007

Circulating gastrin concentrations in patients at increased risk of developing colorectal carcinoma.

scientific article

Circulating gastrin is increased in hemochromatosis

scientific article published on 18 October 2006

Comparison of transferrin sequences from different species.

scientific article published on September 1993

Comparison of two syngeneic orthotopic murine models of pancreatic adenocarcinoma.

scientific article published on 19 August 2013

Controlled overexpression of selected domains of the P85 subunit of phosphatidylinositol 3-kinase reverts v-Ha-Ras transformation.

scientific article

Cyclooxygenase-2-selective antagonists do not inhibit growth of colorectal carcinoma cell lines

scientific article published on 01 January 1998

Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro

scientific article

Developmental expression and biological activity of gastrin-releasing peptide and its receptors in the kidney

scientific article published on 12 May 2004

Divergent roles for ferric ions in the biological activity of amidated and non-amidated gastrins.

scientific article

Do NSAIDs contribute to acute fatty liver of pregnancy?

scientific article published on 01 May 2000

Expression and function of gastrin-releasing peptide (GRP) in normal and cancerous urological tissues

scientific article published on March 2014

Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth

scientific article published on 15 January 2009

Expression of gastrin, gastrin/CCK-B and gastrin/CCK-C receptors in human colorectal carcinomas

scientific article published on 01 January 1995

Expression of gastrin/CCK-B receptors does not lead to a mitogenic response to gastrin in two colon cell lines

scientific article published on September 1999

Ferric ions are essential for the biological activity of the hormone glycine-extended gastrin.

scientific article published on 20 September 2002

Ferric ions inhibit proteolytic processing of progastrin

scientific article

Gastrin and gastrin receptor antagonists bind to both N- and C-terminal halves of the 78 kDa gastrin-binding protein.

scientific article

Gastrin and the transforming protein of polyoma virus have evolved from a common ancestor ⬇️

scientific article published on January 11, 1982

Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor.

scientific article published on 8 October 2010

Gastrin is not required for liver regeneration

scientific article published on 01 January 2008

Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo.

scientific article

Gastrin-deficient mice have disturbed hematopoiesis in response to iron deficiency

scientific article

Gastrin-releasing peptide: different forms, different functions.

scientific article published on January 2009

Gastrins, iron and colorectal cancer.

scientific article published on 28 July 2009

Gastrins, iron homeostasis and colorectal cancer ⬇️

scientific article published on February 12, 2011

Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases

scientific article

Glaucarubinone inhibits colorectal cancer growth by suppression of hypoxia-inducible factor 1α and β-catenin via a p-21 activated kinase 1-dependent pathway.

scientific article

Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line

scientific article published on November 1997

Glycine-extended gastrin stimulates cell proliferation and migration through a Rho- and ROCK-dependent pathway, not a Rac/Cdc42-dependent pathway.

scientific article

Gut hormones, growth and malignancy

scientific article published on January 1994

HIF1α expression under normoxia in prostate cancer--which pathways to target?

scientific article

High-performance liquid chromatography of amino acids, peptides and proteins

scientific article published on 01 August 1984

Identification of a 70-kDa gastrin-binding protein on DLD-1 human colorectal carcinoma cells

scientific article

Identification of binding sites for C-terminal pro-gastrin-releasing peptide (GRP)-derived peptides in renal cell carcinoma: a potential target for future therapy.

scientific article published on 26 January 2015

Identity and regulation of stored and secreted progastrin-derived peptides in sheep

scientific article

Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions

scientific article published on 13 November 2014

Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF).

scientific article

Inhibition of cell proliferation by the cholecystokinin antagonist L-364,718.

scientific article published on January 1991

Inhibition of the preferential binding of actin to the N-terminal hydratase domain of the 78-kDa gastrin-binding protein by non-steroidal anti-inflammatory drugs and gastrin receptor antagonists

scientific article published in May 2001

Interaction of gastrin with transferrin: effects of ferric ions

scientific article published on June 1988

Interrelationships between circulating gastrin and iron status in mice and humans

scientific article published on 28 August 2008

Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinases in glycine-extended gastrin-induced dissociation and migration of gastric epithelial cells.

scientific article

Isolation and partial amino acid sequence of a 78 kDa porcine gastrin-binding protein.

scientific article

Kinetic studies on the mechanism of chorismate mutase/prephenate dehydratase from Escherichia coli K12.

scientific article published in January 1983

Metal ion-dependent binding of gastrin to albumin

scientific article published on 01 December 1991

Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo

scientific article

Molecular cloning and sequence of the ovine gastrin gene.

scientific article

Monoclonal antibody to the gastrin receptor on parietal cells recognizes a 78-kDa protein.

scientific article

Mutation of lysine residues of the 78-kDa gastrin-binding protein reduces gastrin binding

scientific article published in July 2001

Normoxic regulation of HIF-1α in prostate cancer

scientific article published on 01 July 2014

Overexpression of sense or antisense human gastrin mRNA does not affect proliferation of normal rat kidney fibroblasts

scientific article published on March 1999

P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.

scientific article

P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1α.

scientific article published on 26 June 2013

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

scientific article published in June 2010

PCR cloning and sequence of gastrin mRNA from carcinoma cell lines

scientific article published on July 1990

Phosphorylation of a synthetic gastrin peptide by the tyrosine kinase of A431 cell membranes

scientific article published on 01 December 1982

Phosphorylation of cyclin-dependent kinase 2 peptides enhances metal binding

scientific article published on 25 December 2008

Phylogenetic analysis of the sequences of gastrin-releasing peptide and its receptors: biological implications.

scientific article published on 27 February 2007

Platelet-derived growth factor induces phosphatidylinositol 3-kinase release from the middle T-pp60c-src complex and association with the platelet-derived growth factor receptor

scientific article published on January 1994

Preliminary crystallographic data for β-lactamase I from Bacillus cereus 569 ⬇️

scientific article published on April 15, 1978

Preparation and properties of recombinant rat and human procholecystokinin(57-95).

scientific article published in April 2008

Preparation of biologically active recombinant human progastrin(1-80).

scientific article published on October 2002

Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo.

scientific article

Production, secretion, and biological activity of the C-terminal flanking peptide of human progastrin

scientific article published on 22 August 2006

Properties of the complex between recombinant human progastrin and ferric ions

scientific article

Quantitative measurement of mRNA coding for the receptors controlling acid secretion in the ovine fundus and antrum by using RT-PCR

scientific article published on 01 November 2000

Recombinant C-terminal fragments of the gastrin-releasing peptide precursor are bioactive.

scientific article published on 29 March 2007

Reduction in platelet-derived growth factor receptor mRNA in v-src-transformed fibroblasts

scientific article published on April 1995

Related GAP domains in inositol polyphosphate 5-phosphatase and the p85 subunit of phosphatidylinositol 3-kinase

scientific article

Rho GTPases and p21-activated kinase in the regulation of proliferation and apoptosis by gastrins.

scientific article published on 15 May 2008

Selective, high-affinity binding of ferric ions by glycine-extended gastrin(17).

scientific article

Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa

scientific article published in November 2001

Structural requirements for the binding of non-steroidal anti-inflammatory drugs to the 78 kDa gastrin binding protein

scientific article published on 01 June 1999

Synthesis, expression and biological activity of the prohormone for gastrin releasing peptide (ProGRP).

scientific article published on 13 October 2005

The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway ⬇️

scientific article published on August 19, 2010

The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo.

scientific article published on 3 June 2013

The beta-subunit of the gastric H+/K(+)-ATPase can occur without the alpha-subunit

scientific article published in October 1990

The effects of nonspecific HIF1α inhibitors on development of castrate resistance and metastases in prostate cancer

scientific article published on 27 January 2014

The role of hypoxia-inducible factor 1α in determining the properties of castrate-resistant prostate cancers

scientific article

The self-association of chorismate mutase/prephenate dehydratase from Escherichia coli K12

scientific article published on 01 October 1981

The seventh transmembrane domain of gastrin/CCK receptors contributes to non-peptide antagonist binding.

scientific article published on June 1994

Tyrosine modification increases the affinity of gastrin for ferric ions.

scientific article

Zinc ions upregulate the hormone gastrin via an E-box motif in the proximal gastrin promoter

scientific article published on 20 December 2013

p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways

scientific article published on 10 January 2013

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