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List of works by Catarina R. Oliveira

A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats

scientific article published on 4 January 2013

A possible role for oxidation stress in lymphoid leukaemias and therapeutic failure

scientific article published on 7 April 2012

A second look into the oxidant mechanisms in Alzheimer's disease

scientific article

A study of the electrochemical oxidation of Navelbine

scientific article published on 01 March 1993

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

scientific article published on 20 April 2016

Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.

scientific article published on 20 May 2014

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells.

scientific article published on 28 August 2013

Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria

scientific article published on 13 May 2013

Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus.

scientific article published in January 2005

Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801.

scientific article

Adenosine A3 receptors are located in neurons of the rat hippocampus

scientific journal article

Adenosine modulation of d-[3H]aspartate release in cultured retina cells exposed to oxidative stress

scientific article published on 01 March 2000

Adult abdominal Burkitt lymphoma with isolated peritoneal involvement

scientific article published on January 2014

Allelic polymorphism of human FcγRIIA-H/R131 receptor in American tegumentary leishmaniasis ⬇️

scientific article published on February 16, 2011

Alteration of nitric oxide synthase activity upon oxidative stress in cultured retinal cells

scientific article published on 01 March 1998

Aluminium-induced impairment of Ca2+ modulatory action on GABA transport in brain cortex nerve terminals.

scientific article

Aluminum accumulation and membrane fluidity alteration in synaptosomes isolated from rat brain cortex following aluminum ingestion: effect of cholesterol.

scientific article published in October 2002

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

scientific article published on 7 May 2015

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

scientific article

Alzheimer's disease: a lesson from mitochondrial dysfunction.

scientific article published on October 2007

Alzheimer's disease: the quest to understand complexity.

scientific article published on January 2010

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

scientific article

Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved

scholarly article published 1 March 2005

Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels

scientific article

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

scientific article

Amyloid beta-peptide promotes permeability transition pore in brain mitochondria

scientific article published in December 2001

Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.

scientific article published on 25 June 2011

Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells

scientific article published on 16 May 2014

Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.

scientific article

Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogen-activated protein kinase cascades

scientific article published on 22 August 2008

Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway

scientific article published on January 2011

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

scientific article published on 17 July 2006

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

scientific article published on January 2009

Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2

scientific article

Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus.

scientific article published on 16 April 2007

Ankylosing spondylitis susceptibility and severity--contribution of TNF gene promoter polymorphisms at positions -238 and -308.

scientific article

Antioxidant effect of calcium antagonists on microsomal membranes isolated from different brain areas

scientific article published in November 1991

Antioxidant effect of flavonoids after ascorbate/Fe(2+)-induced oxidative stress in cultured retinal cells.

scientific article published in July 2001

Apoptosis deregulation influences chemoresistance to azaguanine in human leukemic cell lines.

scientific article

Apoptotic cell death induced by hydrogen peroxide in NT2 parental and mitochondrial DNA depleted cells

scientific article published on October 2004

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort

scientific article

Atypical presentation of Leber's hereditary optic neuropathy associated to mtDNA 11778G>A point mutation--A case report

scientific article published on 24 January 2007

Autophagocytosis of mitochondria is prominent in Alzheimer disease

scientific article

Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

scientific article published on 6 September 2014

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

scientific article published in July 2009

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.

scientific article published on 23 June 2009

BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells.

scientific article

Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells.

scientific article published on December 2003

Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors

scientific article published on 11 November 2010

Bilateral Evaluation of the Hand and Wrist in Untreated Early Inflammatory Arthritis: A Comparative Study of Ultrasonography and Magnetic Resonance Imaging

scientific article published on 01 June 2013

Bilateral MR imaging of the hand and wrist in early and very early inflammatory arthritis: tenosynovitis is associated with progression to rheumatoid arthritis.

scientific article published on 21 June 2012

Bioenergetic dysfunction in Huntington's disease human cybrids.

scientific article published on 13 June 2011

Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons

scientific article published on 26 May 2007

Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet

scientific article

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

scientific article published on 2 June 2017

Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.

scientific article

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.

scientific article published on 20 February 2007

Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen.

scientific article

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.

scientific article published on 28 March 2008

Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene

scientific article published in November 2006

CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt-Jakob disease suspected cases with inconclusive 14-3-3 result.

scientific article

Ca(2+) regulation of the carrier-mediated gamma-aminobutyric acid release from isolated synaptic plasma membrane vesicles.

scientific article

Ca(2+)-dependent release of [3H]GABA in cultured chick retina cells

scientific article published in September 1992

Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells

scientific article

Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.

scientific article published in May 2006

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

scientific article published on 27 March 2008

Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria.

scientific article published in October 2005

Cerebrospinal fluid Aβ40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease.

scientific article

Chromate-induced human erythrocytes haemoglobin oxidation and peroxidation: influence of vitamin E, vitamin C, salicylate, deferoxamine, and N-ethylmaleimide

scientific article published on 01 April 2000

Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum

scientific journal article

CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats.

scientific article published on 29 August 2005

Cobalt staining of hippocampal neurons mediated by non-desensitizing activation of AMPA but not kainate receptors

scientific article

Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models

scientific article

Comparative study of microglia activation induced by amyloid-beta and prion peptides: role in neurodegeneration

scientific article

Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics

scientific article published in March 2016

Complete screening for glucocerebrosidase mutations in Parkinson disease patients from Portugal

scientific article published on 21 December 2007

Compromised mitochondrial complex II in models of Machado-Joseph disease.

scientific article

Contribution of plasma membrane and endoplasmic reticulum Ca(2+)-ATPases to the synaptosomal [Ca2+]i increase during oxidative stress

scientific article

Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

scientific article published on 21 May 2010

Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration.

scientific article published on 11 January 2013

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α

scientific journal article

Cytochrome c oxidase is decreased in Alzheimer's disease platelets

scientific article published in January 2004

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

scientific article

DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA

scientific article

Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats

scientific article published in August 2003

Detailed characterization of alterations of chromosomes 7, 9, and 10 in glioblastomas as assessed by single-nucleotide polymorphism arrays.

scientific article

Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients

scientific article published on 6 May 2009

Different roles of adenosine A1, A2A and A3 receptors in controlling kainate-induced toxicity in cortical cultured neurons.

scientific article published in October 2005

Different synaptic and subsynaptic localization of adenosine A2A receptors in the hippocampus and striatum of the rat.

scientific article published in January 2005

Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide

scientific article published on 19 October 2005

Distinct glycolysis inhibitors determine retinal cell sensitivity to glutamate-mediated injury

scientific article published in March 1999

Dual Effect of Lipid Peroxidation on the Membrane Order of Retinal Cells in Culture

article

Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus

scientific journal article

Dynamic contrast-enhanced 3-T magnetic resonance imaging: a method for quantifying disease activity in early polyarthritis

scientific article published on 12 February 2011

Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology

scientific article

Dysregulation of CREB activation and histone acetylation in 3-nitropropionic acid-treated cortical neurons: prevention by BDNF and NGF.

scientific article published on 25 September 2009

ER stress is involved in Abeta-induced GSK-3beta activation and tau phosphorylation

scientific article published in July 2008

ER stress-mediated apoptotic pathway induced by Abeta peptide requires the presence of functional mitochondria.

scientific article

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

scientific article

Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

scientific article

Effect of free radicals on adenosine A(2A) and dopamine D2 receptors in the striatum of young adult and aged rats

scientific article published in October 2004

Effect of glucose deprivation and acute glutamate exposure in cultured retinal cells.

scientific article published in September 1998

Effect of oxidative stress on the release of [3H]GABA in cultured chick retina cells

scientific article published on 01 August 1994

Effect of streptozotocin-induced diabetes on rat brain mitochondria

scientific article published in January 2004

Effect of α-synuclein on amyloid β-induced toxicity: relevance to Lewy body variant of Alzheimer disease

scientific article

Effects of 1,4-dihydropyridine derivatives (cerebrocrast, gammapyrone, glutapyrone, and diethone) on mitochondrial bioenergetics and oxidative stress: a comparative study

scientific article published in August 2003

Effects of NADH and H2O2 on Chromate-Induced Human Erythrocytes Hemoglobin Oxidation and Peroxidation

scientific article published on 01 September 2000

Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease

scientific article published on 16 April 2009

Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers

scientific article published on 16 July 2012

Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats

scientific article published in August 2003

Enhanced amyloidogenic processing of amyloid precursor protein and cell death under prolonged endoplasmic reticulum stress in brain endothelial cells.

scientific article published on 17 August 2014

Epigenetics in neurodegeneration: a new layer of complexity.

scientific article published on 22 August 2010

Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats.

scientific article

Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

scientific article published on 14 July 2008

Evidence that synaptobrevin is involved in fusion between synaptic vesicles and synaptic plasma membrane vesicles

scientific article published in July 1997

Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease

scientific article

Expression and subcellular localization of a novel nuclear acetylcholinesterase protein

scientific article published on 2 July 2007

Expression of AMPA/kainate receptors during development of chick embryo retina cells: in vitro versus in vivo studies

scientific article

Expression of functional N-methyl-D-aspartate receptors during development of chick embryo retina cells: in vitro versus in vivo studies

scientific article published in March 2002

FK506 ameliorates cell death features in Huntington's disease striatal cell models.

scientific article published on 15 June 2011

Family association study between DRD2 and DRD3 gene polymorphisms and schizophrenia in a Portuguese population

scientific article published in March 2004

Frontotemporal dementia and mitochondrial DNA transitions

scientific article published in March 2004

G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort

scientific article published in December 2005

Galantamine protects against oxidative stress induced by amyloid-beta peptide in cortical neurons

scientific article published in February 2009

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

scientific article

Genetic variability in CLU and its association with Alzheimer's disease

scientific article

Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.

scientific article published in January 2004

Glutamate increases the [Ca2+]i but stimulates Ca(2+)-independent release of [3H]GABA in cultured chick retina cells

scientific article published in May 1993

Glutamate regulates the viability of retinal cells in culture

scientific article published in March 2001

Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress

scientific article published on January 1997

Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells

scientific article published on 01 February 2000

Glutathione cycle impairment mediates A beta-induced cell toxicity

scientific article published in March 2003

Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.

scientific article published on 14 September 2012

Homovanilic acid in Huntington's disease and Sydenham's chorea

scientific article

Human Erythrocytes Are Protected against Chromate-Induced Peroxidation

scientific article published on 01 May 1999

Hydroxytamoxifen protects against oxidative stress in brain mitochondria.

scientific article

IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

scientific article

Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters

scientific article published on 20 October 2010

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

scientific article published on 13 August 2014

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

scientific article published on January 2017

Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats

scientific article

Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress

scientific article published on 22 June 2006

Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure.

scientific article published in June 2003

Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria

scientific article published on March 2002

Influence of gamma-aminobutyric acid on retinal cells excitotoxicity upon glucose deprivation.

scientific article published in May 1999

Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress

scientific article published on 01 June 1999

Influence of vitamin E succinate on retinal cell survival

scientific article published in July 1998

Inhibition of NF-kB Renders Cells more Vulnerable to Apoptosis Induced by Amyloid ß Peptides

scientific article published on September 2003

Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides

scientific article published in September 2003

Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons ⬇️

scientific article published on September 28, 2012

Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells

scientific article published on 30 June 2014

Insulin attenuates diabetes-related mitochondrial alterations: a comparative study.

scientific article published in May 2006

Insulin in Central Nervous System: More than Just a Peripheral Hormone ⬇️

scientific article published on February 21, 2012

Insulin is a two-edged knife on the brain

scientific article published on January 2009

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

scientific article

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression

scientific article

Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.

scientific article published on April 2005

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

scientific article published in October 2006

Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation

scientific article published on 12 January 2012

Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

scientific article

Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia.

scientific article published in April 2008

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

scientific article published on 01 June 1999

Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides

scientific article published in March 2003

Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide.

scientific article

Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).

scientific article published on 6 November 2007

Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide

scientific article published on January 2003

Lack of evidence for functional TRPV1 vanilloid receptors in rat hippocampal nerve terminals

scientific article published on 2 May 2006

Lack of replication of association between GIGYF2 variants and Parkinson disease.

scientific article

Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers

scientific article published on 16 March 2013

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.

scientific article published on September 2007

Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients

Localization and Trafficking of Amyloid-β Protein Precursor and Secretases: Impact on Alzheimer's Disease

scientific article

Loss of proteostasis induced by amyloid beta peptide in brain endothelial cells

scientific article published on 28 February 2014

Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview

scientific article

Membrane lipid peroxidation induces changes in gamma-[3H]aminobutyric acid transport and calcium uptake by synaptosomes.

scientific article

Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities

scientific article published on 16 March 2012

Metformin promotes isolated rat liver mitochondria impairment.

scientific article published on 2 October 2007

Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes.

scientific article published in July 2008

Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology.

scientific article published on 11 October 2016

Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease

scientific article

Mitochondria as a therapeutic target in Alzheimer's disease and diabetes

scientific article published on December 2009

Mitochondria as potential targets in antidiabetic therapy

scientific article published on January 2011

Mitochondria as the target for mildronate's protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria.

scientific article published in September 2008

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

scientific article

Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen

scientific article published on 13 October 2010

Mitochondria: the common upstream driver of amyloid-β and tau pathology in Alzheimer's disease.

scientific article published on August 2011

Mitochondrial DNA variants in a portuguese population of patients with Alzheimer's disease

scientific article

Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD.

scientific article published on 16 January 2011

Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer's-Disease Related Pathology

scientific article published on 17 June 2016

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

scientific article published in August 2003

Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria.

scientific article published on 29 March 2013

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases ⬇️

scientific article published on October 1, 2003

Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

scientific article

Mitochondrial function is differentially affected upon oxidative stress

scientific article

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

scientific article

Mitochondrial preconditioning: a potential neuroprotective strategy

scientific article published on 26 August 2010

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.

scientific article published on 23 May 2013

Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

scientific article

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

scientific article

Modification of adenosine A1 and A2A receptor density in the hippocampus of streptozotocin-induced diabetic rats

scientific article published on 26 October 2005

Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats

scientific article

Modulation of N-methyl-d-aspartate receptor activity by oxidative stress conditions in chick retinal cells

scientific article published on 01 October 1995

Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.

scientific article published in July 2005

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

scientific article

N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.

scientific article

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

article

Neuroprotective effect of H. perforatum extracts on beta-amyloid-induced neurotoxicity.

scientific article

Neuroprotective effects of statins in an in vitro model of Alzheimer's disease.

scientific article

Neurotoxicity of heroin-cocaine combinations in rat cortical neurons

scientific article published on 30 June 2010

Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases

article

Overactivation of calcineurin induced by amyloid-beta and prion proteins

scientific article

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment

scientific article published in January 2010

Oxidative stress affects synaptosomal gamma-aminobutyric acid and glutamate transport in diabetic rats: the role of insulin

scientific article

Oxidative stress affects the selective ion permeability of voltage-sensitive Ca2+ channels in cultured retinal cells

scientific article published on 01 April 1997

Oxidative stress in acidic conditions increases the production of inositol phosphates in chick retinal cells in culture

article

Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids

scientific article

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

scientific article published on 6 April 2015

Oxidative stress mediates apoptotic effects of ascorbate and dehydroascorbate in human Myelodysplasia cells in vitro.

scientific article published on 27 March 2013

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

scientific article

P3-375

Parameters affecting fusion between liposomes and synaptosomes. Role of proteins, lipid peroxidation, pH and temperature

scientific article published on 01 November 1994

Parkinson's disease and mitochondrial DNA NADH dehydrogenase subunit 1 nucleotides 3337-3340: study in a population from the central region of Portugal (Coimbra).

scientific article published in January 2003

Partition coefficients of dopamine antagonists in brain membranes and liposomes

scientific article published on 01 July 1989

Partition of ca2+ antagonists in brain plasma membranes

scientific article published on 01 July 1989

Partitioning and membrane disordering effects of dopamine antagonists: influence of lipid peroxidation, temperature, and drug concentration

scientific article published on May 15, 1992

Pediatric mitochondrial respiratory chain disorders in the Centro region of Portugal

scientific article published in May 2009

Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment

scientific article

Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

scientific journal article

Pre-clinical antitumour evaluation of Biphosphinic Palladacycle Complex in human leukaemia cells

scientific article published on 5 November 2008

Presynaptic kainate receptors are localized close to release sites in rat hippocampal synapses.

scientific article published in October 2005

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

scientific article published on 27 March 2018

Prion protein aggregation and neurotoxicity in cortical neurons

scientific article

Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer's disease.

scientific article

Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a Portuguese cohort

scientific article published on 6 September 2013

Protective effect of leptin and ghrelin against toxicity induced by amyloid-β oligomers in a hypothalamic cell line.

scientific article published on March 2014

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

scientific article published on January 2005

Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.

scientific article published on 13 December 2006

Pseudohypoparathyroidism type I-b with neurological involvement is associated with a homozygous PTH1R mutation.

scientific article published on 14 July 2016

Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia

scientific article

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

scientific article

Relevant Factors on Cognitive Evaluation of the Portuguese Population

scientific article published on 28 April 2017

Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies.

scientific article published on 27 October 2007

Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus

scientific article

Sporadic Creutzfeldt–Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3γ assay

scientific article published on 03 March 2016

Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons

scientific article published on 23 January 2007

Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus

scientific journal article

Subsynaptic localization of nicotinic acetylcholine receptor subunits: a comparative study in the mouse and rat striatum

scientific article published on 4 March 2014

Susceptibility of hippocampal neurons to Abeta peptide toxicity is associated with perturbation of Ca2+ homeostasis

scientific article

Susceptibility to beta-amyloid-induced toxicity is decreased in goto-kakizaki diabetic rats: involvement of oxidative stress.

scientific article published on January 2000

Synaptic and sub-synaptic localization of amyloid-β protein precursor in the rat hippocampus

scientific article published in January 2014

Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship

scientific article

Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

scientific article published on 12 January 2006

The Association of Amyloid-β Protein Precursor With α- and β-Secretases in Mouse Cerebral Cortex Synapses Is Altered in Early Alzheimer's Disease.

scientific article published on 26 October 2015

The Use of Microcarrier Beads in Ion Transport NMR Studies of Perfused Cells

scientific article published on 01 July 1995

The protective effect of vitamin E, idebenone and reduced glutathione on free radical mediated injury in rat brain synaptosomes.

scientific article published in May 1998

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

scientific article

The role of calcineurin in amyloid-beta-peptides-mediated cell death

scientific article published on July 2005

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease.

scientific article published on 14 May 2014

Therapeutic potential of oxidant mechanisms in Alzheimer's disease

scientific article

Thermodynamic analysis of antagonist and agonist interactions with dopamine receptors

scientific article

Transarterial embolisation of a large focal nodular hyperplasia, using microspheres, in a paediatric patient

scientific article published on 10 July 2015

Transcriptome analysis describing new immunity and defense genes in peripheral blood mononuclear cells of rheumatoid arthritis patients

scientific article

Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus

scientific article published in November 2002

Transthyretin decrease in plasma of MCI and AD patients: investigation of mechanisms for disease modulation

scientific article published in October 2012

Trolox protection of myelin membrane in hydrogen peroxide-treated mature oligodendrocytes

scientific article

Type 2 diabetes aggravates Alzheimer's disease-associated vascular alterations of the aorta in mice

scientific article

Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies

scientific article

Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?

scientific article

Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats

scientific article published on April 2005

Update on persistent symptoms associated with Lyme disease.

scientific article published on February 2015

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

scientific article published on 15 May 2015

Value of brain magnetic resonance imaging in mitochondrial respiratory chain disorders

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Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death

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