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List of works by Seth J Orlow

25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase

scientific article published on August 2004

A Review of Vitamin D and Scarring: The Potential for New Therapeutics

scientific article published on 01 July 2020

A study of large congenital melanocytic nevi and associated malignant melanomas: review of cases in the New York University Registry and the world literature

scientific article published on March 1997

AIDS-associated Kaposi's sarcoma in Romanian children.

scientific article

Abortive segmental perineal hemangioma

scientific article published on 15 October 2011

Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A.

scientific article published on April 2003

Acquired acrodermatitis enteropathica due to zinc-depleted parenteral nutrition

scientific article published on 24 May 2019

Additional glomangioma families link to chromosome 1p: no evidence for genetic heterogeneity.

scientific article

Albendazole sensitizes cancer cells to ionizing radiation.

scientific article

Albinism: an update

scientific article published on March 1997

Altered N-glycosylation in macrophage x melanoma fusion hybrids

scientific article published on November 1999

Alternative Systemic Treatments for Vitiligo: A Review

scientific article published on 02 September 2015

Analysis of 54 cases of hypopigmentation and hyperpigmentation along the lines of Blaschko

scientific article published on October 1996

Androgenetic alopecia in the paediatric population: a retrospective review of 57 patients.

scientific article published on 23 March 2010

Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells

scientific article

Atypical erythema toxicum neonatorum of delayed onset in a term infant

scientific article published on 01 March 1999

Bathing and Associated Treatments in Atopic Dermatitis

scientific article published on 3 December 2016

Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum ⬇️

scientific article published on November 1, 1979

CHILD syndrome in a boy

scientific article published on 01 March 1996

Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells

scientific article

Changes in expression of putative antigens encoded by pigment genes in mouse melanomas at different stages of malignant progression

scientific article

Characterization of Herpes Simplex Virus Infections Seen in the Pediatric Dermatology Office

scientific article published on 21 June 2017

Characterization of a calmodulin-binding protein that is deficient in trifluoperazine-resistant variants of the macrophage-like cell line J774.

scientific article published on January 1983

Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content

scientific article

Cimetidine therapy for multiple viral warts in children

scientific article published on 01 May 1993

Clinical evidence for washing and cleansers in acne vulgaris: A systematic review

scientific article published on 20 February 2018

Clinicopathologic findings in the Bannayan-Riley-Ruvalcaba syndrome

scientific article

Cole Disease Results from Mutations in ENPP1.

scientific article published on 26 September 2013

Cole Disease: Guttate Hypopigmentation and Punctate Palmoplantar Keratoderma

scientific article published on 01 April 2009

Comparative decreases in tyrosinase, TRP-1, TRP-2, and Pmel 17/silver antigenic proteins from melanotic to amelanotic stages of syngeneic mouse cutaneous melanomas and metastases

scientific article published on 01 April 1998

Comparison of Childhood Vitiligo Presenting with or without Associated Halo Nevi

scientific article published on 17 November 2015

Congenital Spitz nevus clinically mimicking melanoma

scientific article published on 01 September 2002

Congenital disorders of hypopigmentation.

scientific article published on March 1995

Congenital granular cell tumors localized to the arm

scientific article published on 01 May 2001

Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes

scientific article

Culinary Metaphors in Dermatology: Eating Our Words

scientific article published on 25 February 2015

Cutaneous features of Crouzon syndrome with acanthosis nigricans

scientific article published on June 2013

Cutaneous findings in craniofacial malformation syndromes

scientific article published on October 1, 1992

Cutaneous microbiome effects of fluticasone propionate cream and adjunctive bleach baths in childhood atopic dermatitis.

scientific article

Cutaneous ulcerations secondary to interferon alfa therapy of Kaposi's sarcoma

scientific article published on 01 April 1992

Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation.

scientific article

Dermatologists' attitudes, prescription, and counseling patterns for isotretinoin: a questionnaire-based study

scientific article

Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research.

scientific article published on January 2009

Dissection of melanogenesis with small molecules identifies prohibitin as a regulator

scientific article published in April 2005

Early-onset childhood vitiligo is associated with a more extensive and progressive course

scientific article published on 25 June 2015

Eccrine angiomatous hamartoma

scientific article published on 08 September 2006

Efficacy and safety of oral retinoids in psoriasis.

scientific article

Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies

scientific article published on 01 August 2006

Engineering a new mouse model for vitiligo

scientific article published on 01 July 2012

Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism

scientific article published on 21 June 2009

Erythema induratum of Bazin in an infant

scientific article published on 01 February 1999

Evidence that dopachrome tautomerase is a ferrous iron-binding glycoprotein

scientific article published in May 1992

Evidence-based recommendations for the diagnosis and treatment of pediatric acne.

scientific article

Expression of tyrosinase and the tyrosinase related proteins in the Mitfvit (vitiligo) mouse eye: implications for the function of the microphthalmia transcription factor

scientific article published on 01 April 1998

Extensive Riga-Fede disease of the lip and tongue

scientific article published on 01 September 2002

Familial segregation of hemangiomas and vascular malformations as an autosomal dominant trait

scientific article published on 01 June 1998

Fatal disseminated infection with human herpesvirus-6.

scientific article

Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.

scientific article published on October 2011

From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging.

scientific article

Genetic mapping of a novel familial form of infantile hemangioma

scientific article published on 01 January 1999

Genital melanocytic nevi in children: Experience in a pediatric dermatology practice

scientific article published on 24 December 2013

HIV infection in Romanian children: a call for antiretroviral therapy

scientific article published on 01 October 1993

High-Value Dermatology: Five Laboratory Tests to Reconsider

scientific article published on 19 December 2017

High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex

scientific article (publication date: August 1994)

IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis

scientific article published on 30 April 2013

Identification and characterization of a melanocyte-specific novel 65-kDa peripheral membrane protein.

scientific article

Identification of a mammalian melanosomal matrix glycoprotein

scientific article published on 01 August 1993

Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion

scientific article

Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism

scientific article published in September 2004

Identification of novel pigmentation modulators by chemical genetic screening

scientific article

Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking

scientific article

Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish

scientific article

Immunoassay and immunopurification of macrophage calmodulin-binding protein

scientific article published on 01 January 1987

Increased risk of symptomatic hemangiomas of the airway in association with cutaneous hemangiomas in a "beard" distribution

scientific article published on 01 October 1997

Induction of B16 melanoma melanogenesis by a serum-free synthetic medium

scientific article published on 01 July 1992

Infantile granular parakeratosis: recognition of two clinical patterns

scientific article published in May 2004

Infantile systemic hyalinosis

Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinism ⬇️

scientific article published on October 1, 2011

Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers

scientific article

Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism.

scientific article

Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.

scientific article published on 20 June 2016

Interaction of melanosomal proteins with melanin.

scientific article

Interactions between ultraviolet light and interleukin-1 on MSH binding in both mouse melanoma and human squamous carcinoma cells

scientific article published on March 1991

Interferon alfa-2a therapy for extensive perianal and lower extremity hemangioma

scientific article published on 01 July 1993

Internal binding sites for MSH: analyses in wild-type and variant Cloudman melanoma cells.

scientific article published in January 1990

Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis

scientific article published in March 2001

Inverse correlation between pink-eyed dilution protein expression and induction of melanogenesis by bafilomycin A1

scientific article (publication date: October 2001)

Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene.

scientific article published on October 1996

Juvenile amyopathic dermatomyositis

scientific article published on 30 December 2005

Juvenile myelomonocytic leukemia presenting with features of hemophagocytic lymphohistiocytosis in association with neurofibromatosis and juvenile xanthogranulomas.

scientific article

Keratosis Pilaris and its Subtypes: Associations, New Molecular and Pharmacologic Etiologies, and Therapeutic Options

scientific article published on 01 October 2018

Large congenital melanocytic nevi and the risk for the development of malignant melanoma. A prospective study

scientific article published in February 1996

Lichen planopilaris noted during etanercept therapy in a child with severe psoriasis

scientific article published in January 2009

Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells

scientific article published on 01 March 1995

Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein band II

scientific article published on 01 February 1993

Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells

scientific article

Melanocytic proliferations in the setting of vulvar lichen sclerosus: diagnostic considerations

scientific article published on 01 May 2005

Melanogenesis by human uveal melanocytes in vitro

scientific article published on 01 April 1995

Melanoma x macrophage fusion hybrids acquire increased melanogenesis and metastatic potential: altered N-glycosylation as an underlying mechanism

scientific article

Melanomas in children

scientific article published on October 1995

Melanosomal and lysosomal alterations in murine melanocytes following transfection with the v-rasHa oncogene

scientific article published on 01 May 1996

Melanosomal defects in melanocytes from mice lacking expression of the pink-eyed dilution gene: correction by culture in the presence of excess tyrosine

scientific article published on 01 March 1998

Melanosomes are specialized members of the lysosomal lineage of organelles.

scientific article

Membrane glycoproteins common to vesicles and melanosomes in mouse melanoma cells

scientific article published in January 1992

Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2.

scientific article

Misrouting of tyrosinase with a truncated cytoplasmic tail as a result of the murine platinum (cp) mutation

scientific article published on 01 November 1995

Molecular cascades in UV-induced melanogenesis: a central role for melanotropins?

scientific article

Morphea, diabetes mellitus type I, and celiac disease: case report and review of the literature.

scientific article published on January 2010

Mucocutaneous granulomatous disease in a patient with Hermansky-Pudlak syndrome.

scientific article published on October 2014

Mucosal dominant pemphigus vulgaris with anti-desmoplakin autoantibodies

scientific article published in July 2004

Multimodal management of diffuse neonatal hemangiomatosis

scientific article

Multiple pilomatricomas: report of two cases and review of the association with myotonic dystrophy.

scientific article

Multiple subcutaneous leiomyosarcomas in an adolescent with AIDS

scientific article published on August 1, 1992

Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro

scientific article published on 01 October 2000

Mutations in the Desmoglein 4 Gene Underlie Localized Autosomal Recessive Hypotrichosis with Monilethrix Hairs and Congenital Scalp Erosions

article

Neonatal erosions and ulcerations in giant congenital melanocytic nevi

scientific article published on September 1999

Neurocutaneous melanosis: clinical features of large congenital melanocytic nevi in patients with manifest central nervous system melanosis

scientific article published on October 1996

Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability

scientific article

Novel mutations of the tyrosinase (TYR) gene in type I oculocutaneous albinism (OCA1)

scientific article published on 01 January 1997

OA1 Mutations and Deletions in X-Linked Ocular Albinism ⬇️

scientific article published on April 1, 1998

Ocular albinism 1 protein: trafficking and function when expressed in Saccharomyces cerevisiae

scientific article

Oral Antibacterial Therapy for Acne Vulgaris: An Evidence-Based Review.

scientific article published on 2 March 2017

Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner

scientific article published on 22 September 2004

Pathogenesis of the platinum (cp) mutation, a model for oculocutaneous albinism

scientific article published on 01 August 1993

Patient perspectives on the management of atopic dermatitis

scientific article published on 2 May 2006

Patient-reported outcomes in pediatric patients with psoriasis undergoing etanercept treatment: 12-week results from a phase III randomized controlled trial

scientific article published on 8 July 2010

Pegylated liposomal doxorubicin (PLD): enhanced skin toxicity in areas of vitiligo.

scientific article published on 9 December 2008

Phacomatosis pigmentokeratotica associated with hemihypertrophy and a rhabdomyosarcoma of the abdominal wall

scientific article published on 01 August 2006

Pigmented plexiform neurofibroma: Distinction from a large congenital melanocytic nevus

scientific article published on 5 February 2007

Pink-eyed dilution protein controls the processing of tyrosinase.

scientific article published on June 2002

Pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism.

scientific article published on December 2002

Pityriasis rubra pilaris, type IV

scientific article published on 30 December 2005

Porokeratotic eccrine ostial and dermal duct nevus: a report of 2 cases and review of the literature.

scientific article published on August 2009

Postnatal ocular expression of tyrosinase and related proteins: disruption by the pink-eyed unstable (p(un)) mutation

scientific article published in September 1993

Practical guidelines for evaluation of loose anagen hair syndrome

scientific article published in October 2009

Purification and distribution of a novel macrophage-specific calmodulin-binding glycoprotein.

scientific article

Rab27b association with melanosomes: dominant negative mutants disrupt melanosomal movement.

scientific article

Radiation therapy for high-risk squamous cell carcinomas in patients with xeroderma pigmentosum: report of two cases and review of the literature

scientific article published on 21 October 2011

Rapid improvement of prurigo nodularis with cyclosporine treatment

scientific article published on 10 February 2018

Recent advances in understanding vitiligo

scientific article

Regulation of melanogenesis by human uveal melanocytes in vitro

scientific article published on 01 March 1997

Retinoic acid is a potent inhibitor of inducible pigmentation in murine and hamster melanoma cell lines

scientific article published on April 1990

Segmental stiff skin syndrome (SSS): A distinct clinical entity.

scientific article published on 2 March 2016

Skin and bones. I.

scientific article published on August 1991

Speckled lentiginous nevus--classic congenital melanocytic nevus hybrid not the result of "collision"

scientific article published on 01 December 2001

Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi.

scientific article

Spitz nevi: beliefs, behaviors, and experiences of pediatric dermatologists

scientific article

Stimulation of the receptor for melanocyte-stimulating hormone by retinoic acid

scientific article published on December 1990

Structural/functional relationships between internal and external MSH receptors: modulation of expression in Cloudman melanoma cells by UVB radiation

scientific article

Subcellular distribution of tyrosinase and tyrosinase-related protein-1: implications for melanosomal biogenesis.

scientific article

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

scientific article published on 22 August 2012

Supraumbilical midabdominal raphe, sternal atresia, and hemangioma in an infant: response of hemangioma to laser and interferon alfa-2a.

scientific article published on March 1993

Symmetric truncal aplasia cutis congenita following multifetal reduction of a sextuplet pregnancy

scientific article

Syndromes associated with melanocytic nevi

scientific article

Synthesis and characterization of melanins from dihydroxyindole-2-carboxylic acid and dihydroxyindole

scientific article published on 01 September 1992

Teens, Acne, and Oral Contraceptive Pills: The Need for Greater Clarity on When Teens Can Consent

scientific article published in April 2017

The Alopecia Areata Consensus of Experts (ACE) Study: Results of an International Expert Opinion on Treatments for Alopecia Areata

scientific article published on 09 March 2020

The Dermatology Foundation: partnerships and programs focused on the future.

scientific article published in April 2013

The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function

scientific article published in November 1994

The Tyr (albino) locus of the laboratory mouse

scientific article published in October 2004

The Use of Hormonal Antiandrogen Therapy in Female Patients with Acne: A 10-Year Retrospective Study

scientific article published on 20 March 2018

The effects of trifluoperazine on the macrophage-like cell line, J774

scientific article published on 01 January 1980

The extracellular cyclic nucleotide phosphodiesterase of Dictyostelium discoideum. Purification and characterization

scientific article published on 01 July 1981

The misnomer "macrocephaly-cutis marmorata telangiectatica congenita syndrome": report of 12 new cases and support for revising the name to macrocephaly-capillary malformations.

scientific article published on March 2009

The mouse ocular albinism 1 gene product is an endolysosomal protein

scientific article published on 01 March 2001

The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone.

scientific article published on 31 March 2017

The ocular albinism type 1 gene product is an N-glycoprotein but glycosylation is not required for its subcellular distribution

scientific article

The ocular albinism type 1 gene product, OA1, spans intracellular membranes 7 times

scientific article

The physician-scientist

scientific article published in March 2006

The pink-eyed dilution gene and the molecular pathogenesis of tyrosinase-positive albinism (OCA2).

scientific article

The pink-eyed dilution locus controls the biogenesis of melanosomes and levels of melanosomal proteins in the eye

scientific article published on 01 February 1999

The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis

scientific article published on 01 October 1995

The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding

scientific article published on 23 April 2010

The use of oral antibiotics before isotretinoin therapy in patients with acne

scientific article

Tinea incognito in an urban pediatric population

scientific article published on 01 November 2018

Triazine-based tyrosinase inhibitors identified by chemical genetic screening

scientific article published in December 2005

Ulcerated haemangioma of infancy: a retrospective review of 47 patients

scientific article published on 27 February 2007

Undifferentiated pleomorphic sarcoma in a child with type 1 neurofibromatosis

scientific article published on 23 April 2010

Unilateral cutaneous heterotopic meningeal nodules with neural, smooth muscle and connective tissue hamartomas: a field defect of cephalic neural crest-derived tissues

scientific article published on 20 February 2007

Varicella-zoster virus infection in Romanian children infected with the human immunodeficiency virus.

scientific article

Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8.

scientific article

X-linked recessive ichthyosis

scientific article published on 30 December 2005

XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts

scientific article

p16(Ink4a) in melanocyte senescence and differentiation

scientific article published in March 2002

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