List of works by Mattias Höglund

A Molecular Pathologic Framework for Risk Stratification of Stage T1 Urothelial Carcinoma.

scientific article published on 11 March 2015

A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences

scientific article published on 01 November 1998

A gene fusion network in human neoplasia.

scientific article published in April 2006

A human 12p-derived cosmid hybridizing to subsets of human and chimpanzee telomeres

scientific article published in January 1995

A model for karyotypic evolution in testicular germ cell tumors.

scientific article published in July 2004

A molecular taxonomy for urothelial carcinoma.

scientific article published on 2 May 2012

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).

scientific article

A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age- and sex-related differences

scientific article published on 01 March 2003

A radiation hybrid map with 60 loci covering the entire short arm of chromosome 12.

scientific article

A systematic study of gene mutations in urothelial carcinoma; inactivating mutations in TSC2 and PIK3R1.

scientific article

A validation and extended description of the Lund taxonomy for urothelial carcinoma using the TCGA cohort.

scientific article published on 27 February 2018

Abnormal nuclear shape in solid tumors reflects mitotic instability

scientific article published on January 2001

Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer.

scientific article published on 21 August 2018

Acute myeloid leukemia with inv(16)(p13q22): involvement of cervical lymph nodes and tonsils is common and may be a negative prognostic sign

scientific article

Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas

scientific article published in July 2001

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

scientific article published on 16 April 2021

Analysis of fusion transcripts indicates widespread deregulation of snoRNAs and their host genes in breast cancer

scientific article published on 17 February 2020

Analysis of promoter regions of co-expressed genes identified by microarray analysis

scientific article

Approximate geodesic distances reveal biologically relevant structures in microarray data

scientific article

Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study

scientific article

BCR/ABL-negative chronic myeloid leukemia with ETV6/ABL fusion

scientific article published on 01 November 1997

Biological determinants of bladder cancer gene expression subtypes

scientific article published on 8 June 2015

Bladder Cancer Molecular Taxonomy: Summary from a Consensus Meeting

scientific article published on 07 January 2016

Can tissue microarray-based analysis of protein expression predict recurrence of stage Ta bladder cancer?

scientific article published on 20 April 2011

Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes.

scientific article published in August 2017

Characterization of chromosome aberrations in salivary gland tumors by FISH, including multicolor COBRA-FISH

scientific article published on 01 February 2001

Characterization of genomically amplified segments using PCR: optimizing relative-PCR for reliable and simple gene expression and gene copy analyses

scientific article published on October 2000

Characterization of the CHOP breakpoints and fusion transcripts in myxoid liposarcomas with the 12;16 translocation

scientific article (publication date: 15 December 1994)

Childhood acute lymphoblastic leukaemia with ider(21)(q10)t(12;21)(p12;q22): a new recurrent abnormality showing ETV6/CBFA2 fusion

scientific article published on 01 July 1997

Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

scholarly article

Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms

scientific article published on 01 July 1997

Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridization

scientific article

Clinical and genetic studies of ETV6/ABL1-positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate

scientific article

Clustering of deletions on chromosome 13 in benign and low-malignant lipomatous tumors

scientific article

Combined gene expression and genomic profiling define two intrinsic molecular subtypes of urothelial carcinoma and gene signatures for molecular grading and outcome.

scientific article published on 20 April 2010

Comparative genomic hybridization reveals frequent gains of 20q, 8q, 11q, 12p, and 17q, and losses of 18q, 9p, and 15q in pancreatic cancer

article

Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma.

scientific article

Conservation of highly repetitive DNA in cetaceans

scientific article published on 01 January 1984

Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer

scientific article published on 3 March 2005

Construction and preliminary analysis of the ICRF human P1 library

scientific article published on January 1994

Construction of microcell hybrid panel containing different neo gene insertions in mouse chromosome 17 used for chromosome-mediated gene transfer

scientific article published in May 1989

Coping with complexity. multivariate analysis of tumor karyotypes

scientific article

Cyclin D1 amplification in chromosomal band 11q13 is associated with overrepresentation of 3q21-q29 in head and neck carcinomas

scientific article published on 01 March 2002

Cytogenetic aberrations in 188 benign and borderline adipose tissue tumors

scientific article published on 01 March 1994

Cytogenetic analysis of pancreatic carcinomas: intratumor heterogeneity and nonrandom pattern of chromosome aberrations.

scientific article published in October 1998

Cytogenetic and FISH analyses of pancreatic carcinoma reveal breaks in 18q11 with consistent loss of 18q12-qter and frequent gain of 18p.

scientific article

Cytogenetic and FISH studies of a single center consecutive series of 152 childhood acute lymphoblastic leukemias

scientific article published on 01 July 2000

Cytogenetic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinomas: frequent loss of 19p13.3 and gain of 19q13.1-13.2.

scientific article published on 01 January 1998

Cytogenetic and fluorescence in situ hybridization characterization of chromosome 1 rearrangements in head and neck carcinomas delineate a target region for deletions within 1p11-1p13

scientific article published on 01 December 1998

Cytogenetic and fluorescence in situ hybridization characterization of chromosome 8 rearrangements in head and neck squamous cell carcinomas

scientific article published on 01 October 2001

Cytogenetic and molecular genetic demonstration of polyclonality in an acinic cell carcinoma

scientific article

Cytogenetic features of multiple myeloma: impact of gender, age, disease phase, culture time, and cytokine stimulation

scientific article published on 01 June 2002

Cytogenetics of hepatoblastoma: further characterization of 1q rearrangements by fluorescence in situ hybridization: an international collaborative study.

scientific article published in March 2000

DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status

scientific article

Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities

scientific article

Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p.

scientific article published on 18 June 2013

Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification

scientific article published on 01 June 2002

Different pathways for chromosomal integration of transfected circular pSVneo plasmids in normal and established rodent cells

scientific article published on July 1992

Differentially amplified chromosome 12 sequences in low- and high-grade osteosarcoma

scientific article published on 01 February 2002

Dissecting karyotypic patterns in colorectal tumors: two distinct but overlapping pathways in the adenoma-carcinoma transition.

scientific article published in October 2002

Dissecting karyotypic patterns in malignant melanomas: temporal clustering of losses and gains in melanoma karyotypic evolution

scientific article published on 01 January 2004

Dissecting karyotypic patterns in renal cell carcinoma: an analysis of the accumulated cytogenetic data

scientific article

Distinct evolutionary mechanisms for genomic imbalances in high-risk and low-risk neuroblastomas ⬇️

scientific article

Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers.

scientific article published on March 2007

ETV6/ABL fusion is rare in Ph-negative chronic myeloid disorders

scientific article

Ewing tumours and synovial sarcomas have critical features of karyotype evolution in common with epithelial tumours

scientific article published on 01 September 2005

Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUS

scientific article

Extensive cytogenetic heterogeneity in a benign retroperitoneal schwannoma

FISH characterization of head and neck carcinomas reveals that amplification of band 11q13 is associated with deletion of distal 11q

scientific article published on 01 August 1998

Fluorescence in situ hybridization analyses of hematologic malignancies reveal frequent cytogenetically unrecognized 12p rearrangements

scientific article published on 01 March 1998

Fluorescence in situ hybridization analysis of whole-arm 7;12 translocations in hematologic malignancies

scientific article published on 01 September 1995

Fluorescent in situ hybridisation (FISH) characterisation of pericentromeric breakpoints on chromosome 5 in head and neck squamous cell carcinomas.

scientific article published on March 1999

Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer

article

Frequent miRNA-convergent fusion gene events in breast cancer

scientific article published on 5 October 2017

Fusion of the EWS and CHOP genes in myxoid liposarcoma

scientific article

Fusion of the FUS gene with ERG in acute myeloid leukemia with t(16;21)(p11;q22)

scientific article published on 01 December 1994

Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.

scientific article

Genetic Alterations in the Molecular Subtypes of Bladder Cancer: Illustration in the Cancer Genome Atlas Dataset

scientific article

Genetic variant of the human homologous recombination-associated gene RMI1 (S455N) impacts the risk of AML/MDS and malignant melanoma

scientific article

Genome-wide array-based comparative genomic hybridization reveals multiple amplification targets and novel homozygous deletions in pancreatic carcinoma cell lines

scientific article published on May 2004

Genome-wide transcription factor binding site/promoter databases for the analysis of gene sets and co-occurrence of transcription factor binding motifs

scientific article

Genomic amplification of CCND2 is rare in non-Hodgkin lymphomas

scientific article published on 01 April 1998

Genomic profiling of bone and soft tissue tumors with supernumerary ring chromosomes using tiling resolution bacterial artificial chromosome microarrays

scientific article published on 29 May 2006

Genotyping techniques to address diversity in tumors

scientific article published on January 2011

HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts

scientific article published on 24 March 2017

Heterogeneous challenges for urologic cancers

scientific article published on 06 November 2014

Hibernomas are characterized by homozygous deletions in the multiple endocrine neoplasia type I region. Metaphase fluorescence in situ hybridization reveals complex rearrangements not detected by conventional cytogenetics

scientific article published on July 1999

High frequencies of chromosomal aberrations in multiple myeloma and monoclonal gammopathy of undetermined significance in direct chromosome preparation

scientific article

High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization

scientific article

Identification of cytogenetic subgroups and karyotypic pathways in transitional cell carcinoma

scientific article published on 01 November 2001

Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomas

scientific article published in March 2004

Incidence and prognostic significance of karyotypic subgroups in older patients with acute myeloid leukemia: the Swedish population-based experience

scientific article published on 28 February 2014

Independent component analysis reveals new and biologically significant structures in micro array data

scientific article

Infiltration of CD3⁺ and CD68⁺ cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors

scientific article

Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma

scientific article

Isochromosome 17q in blast crisis of chronic myeloid leukemia and in other hematologic malignancies is the result of clustered breakpoints in 17p11 and is not associated with coding TP53 mutations

scientific article published on 01 July 1999

Isolation and characterization of radiation hybrids for human chromosome 12.

scientific article published on January 1995

Isolation and regional localization of cosmid linking clones from human chromosome 12.

scientific article published on June 1994

Locus-specific multifluor FISH analysis allows physical characterization of complex chromosome abnormalities in neoplasia

scientific article published on 01 July 2000

MDS/AML-associated cytogenetic abnormalities in multiple myeloma and monoclonal gammopathy of undetermined significance: Evidence for frequent de novo occurrence and multipotent stem cell involvement of del(20q)

article

MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31

scientific article

Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications

scientific article published on March 2005

Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status

scientific article published on 5 April 2007

Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer

scientific article published on January 1999

Molecular characterization of 12p abnormalities in hematologic malignancies: deletion of KIP1, rearrangement of TEL, and amplification of CCND2

scientific article published on 01 January 1996

Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q.

scientific article published in April 2006

Molecular characterization of jumping translocations reveals spatial and temporal breakpoint heterogeneity

scientific article published on 01 September 1998

Molecular classification of urothelial carcinoma: global mRNA classification versus tumour-cell phenotype classification

scientific article

Molecular cytogenetic mapping of recurrent chromosomal breakpoints in tenosynovial giant cell tumors

scientific article published on 13 April 2002

Molecular pathology of the luminal class of urothelial tumors

scientific article published on 27 August 2019

Molecular profiling reveals low- and high-grade forms of primary melanoma

scientific article

Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.

scholarly article

Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems

scientific article published on 26 May 2015

Monitoring of technical variation in quantitative high-throughput datasets

scientific article published on 23 September 2013

Monochromosomal mouse microcell hybrids containing inserted selectable neo genes

scientific article published on September 1990

More efficient mobilisation of peripheral blood stem cells with HiDAC+AMSA+G-CSF than with mini-ICE+G-CSF in patients with AML.

scientific article

Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced translocations during disease progression.

scientific article published on October 2002

Multivariate analyses of genomic imbalances in solid tumors reveal distinct and converging pathways of karyotypic evolution.

scientific article published in June 2001

Multivariate analysis of chromosomal imbalances in breast cancer delineates cytogenetic pathways and reveals complex relationships among imbalances

scientific article published on 01 May 2002

New probabilistic network models and algorithms for oncogenesis.

scientific article published on May 2006

Non-negative matrix factorization for the analysis of complex gene expression data: identification of clinically relevant tumor subtypes

scientific article

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

scientific article

On the origin of syn- and metachronous urothelial carcinomas.

scientific article published on 16 November 2006

Ovarian carcinoma develops through multiple modes of chromosomal evolution.

scientific article

Paired multiplex reverse-transcriptase polymerase chain reaction (PMRT-PCR) analysis as a rapid and accurate diagnostic tool for the detection of MLL fusion genes in hematologic malignancies

scientific article published on 01 August 2001

Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.

scientific article

Polyclonal expansion of cells with trisomy 7 in synovia from patients with osteoarthritis

scientific article published on 01 January 1998

Power law distribution of chromosome aberrations in cancer

scientific article published on 01 November 2003

Prediction of stage, grade, and survival in bladder cancer using genome-wide expression data: a validation study

scientific article

Prevalence and characteristics of survivors from acute myeloid leukemia in Sweden

scientific article published on 31 October 2016

Promoter analysis of epigenetically controlled genes in bladder cancer.

scientific article published on May 2008

Putting chromosome aberrations on the map

scientific article published on 01 September 2000

Re: David J. McConkey, Woonyoung Choi, Colin P.N. Dinney. New insights into subtypes of invasive bladder cancer: considerations of the clinician. Eur Urol 2014;66:609-10

scientific article published on 04 September 2014

Rearrangement of the neoplasia-associated gene HMGIC in synovia from patients with osteoarthritis.

scientific article published in March 1999

Recurrent and multiple bladder tumors show conserved expression profiles

scientific article

Robust assignment of cancer subtypes from expression data using a uni-variate gene expression average as classifier

scientific article

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

scientific article published on 16 September 2008

Statistical analyses of karyotypic complexity in head and neck squamous cell carcinoma

scientific article published on 01 April 2004

Statistical behavior of complex cancer karyotypes

scientific article

Statistical dissection of cytogenetic patterns in lung cancer reveals multiple modes of karyotypic evolution independent of histological classification

scientific article published in October 2004

Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity

scientific article

Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

scientific article

Telomere shortening and mitotic dysfunction generate cytogenetic heterogeneity in a subgroup of renal cell carcinomas

scientific article published on July 2004

Telomere-mediated mitotic disturbances in immortalized ovarian epithelial cells reproduce chromosomal losses and breakpoints from ovarian carcinoma

scientific article published on January 2005

The Lund Molecular Taxonomy Applied to Non–Muscle-Invasive Urothelial Carcinoma

scientific article published in 2022

The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeats

scientific article

The construction of a beta-lactamase-encoding ApR gene cassette flanked by recognition sites for NotI, SacII, MluI, SplI, BssHII and NarI.

scientific article published in December 1994

The importance of being grade 3: WHO 1999 versus WHO 2004 pathologic grading.

scientific article

The isolation of evolutionarily conserved Eag I end-clones from mouse chromosome 17 using cloned DNA.

scientific article

The origin of the Mendelian Society in Lund and the start of Hereditas

scientific article published on 10 December 2014

The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells

article

The tumor-associated gene HMGIC is expressed in normal and osteoarthritis-affected synovia

scientific article published in April 2001

Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors

scientific article

Tissue microarray based analysis of prognostic markers in invasive bladder cancer: much effort to no avail?

scientific article published on 22 October 2007

Toward a molecular pathologic classification of urothelial carcinoma.

scientific article published on July 2013

Truncation and fusion of HMGA2 in lipomas with rearrangements of 5q32-->q33 and 12q14-->q15

scientific article published on 01 January 2006

Unique cytological features and chromosome aberrations in chondroid lipoma: a case report based on fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and molecular cytogenetics

scientific article published on October 1999

Variable stability of chromosomes containing amplified alpha-satellite sequences in human mesenchymal tumours

scientific article published on September 1999

Vitamin D receptor is expressed in pancreatic cancer cells and a vitamin D3 analogue decreases cell number

scientific article published in January 2003

Wilms tumors develop through two distinct karyotypic pathways.

scientific article

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