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List of works by Anne Le

Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold.

scientific article published on 13 March 2016

Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury

scientific article published on 31 July 2008

Breast Cancer Metabolism

scientific article published on 01 January 2018

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

scientific article

Different Tumor Microenvironments Lead to Different Metabolic Phenotypes

scientific article published on 01 January 2018

Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

scientific article published on 25 August 2016

Dual role of N-acetyl-aspartyl-glutamate metabolism in cancer monitor and therapy

scientific article published on 20 June 2019

Dysregulated metabolism contributes to oncogenesis

scientific article

Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors

scientific article published on 30 May 2013

Glucose Metabolism in Cancer

scientific article published on 01 January 2018

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

scientific journal article

Glutamine Metabolism in Cancer

scientific article published on 01 January 2018

Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment

scientific article published in 2021

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

scientific article

Inhibition of the MYC-regulated glutaminase metabolic axis is an effective synthetic lethal approach for treating chemoresistant cancers

scientific article published on 28 August 2020

MYC-induced cancer cell energy metabolism and therapeutic opportunities

scientific article published on 27 October 2009

Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells

scientific article published on 01 January 2018

Metabolic and electrochemical mechanisms of dimeric naphthoquinones cytotoxicity in breast cancer cells

scientific article published on 8 October 2011

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

scientific article published on 19 October 2020

Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury

scientific article

Non-Hodgkin Lymphoma Metabolism

scientific article published on 01 January 2018

Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation

scientific article published on 09 April 2018

Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema

scientific article published on 11 June 2009

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.

scientific article

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC ⬇️

scientific article published on May 21, 2012

Studying Myc's role in metabolism regulation

scientific article

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.

scientific article published on 27 April 2015

Targeting Metabolic Cross Talk between Cancer Cells and Cancer-Associated Fibroblasts

scientific article published on 01 January 2018

Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment

scientific article published on 4 September 2017

The Heterogeneity of Lipid Metabolism in Cancer

scientific article published on 01 January 2018

The Intratumoral Heterogeneity of Cancer Metabolism

scientific article published on 01 January 2018

The Intricate Metabolism of Pancreatic Cancers

scientific article published on 01 January 2018

The Metabolic Interplay between Cancer and Other Diseases

scientific article published on 21 November 2019

The Metabolism of Renal Cell Carcinomas and Liver Cancer

scientific article published on 01 January 2018

The Multifaceted Metabolism of Glioblastoma

scientific article published on 01 January 2018

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

scientific article

Therapeutic targeting of cancer cell metabolism.

scientific article

Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer

scientific article published on 01 April 2019

Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer

scientific article published on 01 August 2019

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