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List of works by Mark C. Field

A bioinformatic analysis of the RAB genes of Trypanosoma brucei

scientific article

A cell-surface phylome for African trypanosomes

scientific article

A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae

scientific article

A novel Rho-like protein TbRHP is involved in spindle formation and mitosis in trypanosomes

scientific article

A novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila

scientific article published on 19 May 2022

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes

scientific article published on 28 September 2007

Acylation-dependent Protein Export in Leishmania

scientific article published in Journal of Biological Chemistry

Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes

article

Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids ⬇️

scientific article published on January 19, 2013

An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei

scientific article

Analysis of small GTPase function in trypanosomes

scientific article published in January 2008

Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species

scientific article

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

scientific article

Biochemical and genetic evidence for a family of heterotrimeric G-proteins in Trichomonas vaginalis.

scientific article

Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis.

scientific article

Cell density-dependent ectopic expression in bloodstream form Trypanosoma brucei.

scientific article published on 26 March 2013

Chaperone requirements for biosynthesis of the trypanosome variant surface glycoprotein

scientific article

Characterization of a glycosylphosphatidylinositol membrane protein anchor precursor in Leishmania mexicana ⬇️

scientific article published on 01 October 1991

Chromosome-wide analysis of gene function by RNA interference in the african trypanosome.

scientific article published on September 2006

Clathrin-mediated endocytosis is essential in Trypanosoma brucei.

scientific article published on October 2003

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.

scientific article published on 12 September 2016

Comparative interactomics provides evidence for functional specialization of the nuclear pore complex

scientific article published on 2 May 2017

Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins

scientific article

Cytoplasmic targeting signals in transmembrane invariant surface glycoproteins of trypanosomes

scientific article published in September 2004

Developmental variation in Rab11-dependent trafficking in Trypanosoma brucei

scientific article published on May 2005

Differential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools

scientific article

Dileucine signal-dependent and AP-1-independent targeting of a lysosomal glycoprotein in Trypanosoma brucei

scientific article published on 6 August 2007

Dramatic reorganisation of Trichomonas endomembranes during amoebal transformation: a possible role for G-proteins

scientific article published on 31 March 2006

Drug screening by crossing membranes: a novel approach to identification of trypanocides

scientific article published in April 2009

EIF2α phosphorylation is regulated in intracellular amastigotes for generation of infective Trypanosoma cruzi trypomastigote forms

scientific article published on 29 June 2020

ER-associated protein degradation is a common mechanism underpinning numerous monogenic diseases including Robinow syndrome

scientific article published on 27 July 2005

Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes.

scientific article published on 29 May 2012

Erratum to “Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei”

scientific article published in April 2000

Essential roles for GPI-anchored proteins in African trypanosomes revealed using mutants deficient in GPI8

scientific article

Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei

scientific article published in July 2002

Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor

scientific article published on 13 June 2009

Evidence for recycling of invariant surface transmembrane domain proteins in African trypanosomes

scientific article published on 21 December 2012

Evidence that low endocytic activity is not directly responsible for human serum resistance in the insect form of African trypanosomes

scientific article

Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins

scientific article

Evolution of late steps in exocytosis: conservation and specialization of the exocyst complex

scientific article published on 29 November 2019

Evolution of modular intraflagellar transport from a coatomer-like progenitor.

scientific article published on 8 April 2013

Evolution of protein trafficking in kinetoplastid parasites: Complexity and pathogenesis

scientific article published on 24 July 2018

Evolution of the endomembrane systems of trypanosomatids - conservation and specialisation.

scientific article

Evolution of the eukaryotic membrane-trafficking system: origin, tempo and mode

scientific article published on September 2007

Evolution of the karyopherin-β family of nucleocytoplasmic transport factors; ancient origins and continued specialization

scientific article

Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage

scientific article published on 14 July 2008

Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat ⬇️

scientific article

Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

scientific article published on May 2011

Export of a misprocessed GPI-anchored protein from the endoplasmic reticulum in vitro in an ATP- and cytosol-dependent manner

scientific article published on 01 October 2000

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

scientific article

High-throughput decoding of antitrypanosomal drug efficacy and resistance

scientific article published on 25 January 2012

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

scientific article published on 9 February 2018

How complex is GTPase signaling in trypanosomes?

scientific article published on 6 May 2008

Identification of a very large Rab GTPase family in the parasitic protozoan Trichomonas vaginalis

scientific article

Implications of the new eukaryotic systematics for parasitologists

scientific article published on 04 December 2007

Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei

scientific article published on 09 July 2020

Intracellular trafficking in the trypanosomatids

scientific article published on 25 April 2007

Isolation and characterization of subnuclear compartments from Trypanosoma brucei. Identification of a major repetitive nuclear lamina component

scientific article published on 26 July 2001

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

scientific article published in August 2002

Leishmania major: clathrin and adaptin complexes of an intra-cellular parasite

scientific article published on 15 December 2004

Macromolecular trafficking and immune evasion in african trypanosomes.

scientific article published on January 2009

Metabolic quirks and the colourful history of the Euglena gracilis secondary plastid

scientific article published on 04 November 2019

Molecular paleontology and complexity in the last eukaryotic common ancestor

scientific article (publication date: 2013)

Molecular species analysis of phospholipids from Trypanosoma brucei bloodstream and procyclic forms

scientific article published in March 1993

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

scientific article published on 09 July 2019

NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions

scientific article (publication date: 2012)

New approaches to the microscopic imaging of Trypanosoma brucei.

scientific article

Perturbation of local endogenous expression by insertion of Pol I expression constructs into the genome of Trypanosoma brucei

scientific article published in March 2005

Phylogeny of endocytic components yields insight into the process of nonendosymbiotic organelle evolution

scholarly article

Pore timing: the evolutionary origins of the nucleus and nuclear pore complex

scientific article published on 03 April 2019

Proteomic analysis of clathrin interactions in trypanosomes reveals dynamic evolution of endocytosis.

scientific article

Proteomics Uncovers Novel Components of an Interactive Protein Network Supporting RNA Export in Trypanosomes

scientific article published on 26 January 2022

Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes ⬇️

scientific article published on February 6, 2012

Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines

scientific article published on 27 November 2012

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly

scientific article

RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei.

scientific article

Rab protein evolution and the history of the eukaryotic endomembrane system

scientific article published on 26 June 2010

Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners

scientific article published on 3 June 2011

Rab23 is a flagellar protein in Trypanosoma brucei

scientific article

Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways

scientific article published on 18 November 2011

Rab4 is an essential regulator of lysosomal trafficking in trypanosomes

scientific article

Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei

scientific article published on September 2003

Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy.

scientific article published on 17 April 2013

Reconstitution of glycopeptide export in mixed detergent-solubilised and resealed microsomes depleted of lumenal components

scientific article published in January 2005

Regulation of early endosomes across eukaryotes: Evolution and functional homology of Vps9 proteins

scientific article published on 30 March 2018

Regulation of thromboxane receptor signaling at multiple levels by oxidative stress-induced stabilization, relocation and enhanced responsiveness

scientific article

Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases

scientific article

Sequence divergence in a family of variant surface glycoprotein genes from trypanosomes: coding region hypervariability and downstream recombinogenic repeats

scientific article published in May 1996

Specialising the parasite nucleus: Pores, lamins, chromatin, and diversity.

scientific article

Specializations in a successful parasite: what makes the bloodstream-form African trypanosome so deadly?

scientific article published on 07 July 2011

Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes

scientific article published on 30 April 2020

TbFRP, a novel FYVE-domain containing phosphoinositide-binding Ras-like GTPase from trypanosomes

scientific article published on 3 December 2012

TbRAB1 and TbRAB2 mediate trafficking through the early secretory pathway of Trypanosoma brucei

scientific article published on October 2004

TbRAB18, a developmentally regulated Golgi GTPase from Trypanosoma brucei

scientific article

TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation.

scientific article

Terminal galactosylation of glycoconjugates in Plasmodium falciparum asexual blood stages and Trypanosoma brucei bloodstream trypomastigotes ⬇️

scientific article published on March 3, 2012

The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility

scientific article

The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system.

scientific article

The farnesyltransferase inhibitor manumycin A is a novel trypanocide with a complex mode of action including major effects on mitochondria.

scientific article published in October 1999

The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells

scientific article published on 28 October 2003

The role of alternative splicing and C-terminal amino acids in thromboxane receptor stabilization

scientific article

The single ENTH-domain protein of trypanosomes; endocytic functions and evolutionary relationship with epsin

scientific article published on 17 March 2009

The single dynamin-like protein of Trypanosoma brucei regulates mitochondrial division and is not required for endocytosis

scientific article

The trypanosome Rab-related proteins RabX1 and RabX2 play no role in intracellular trafficking but may be involved in fly infectivity.

scientific article

The trypanosome flagellar pocket.

scientific article published on 06 October 2009

The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages

scientific article

Transcriptome, proteome and draft genome of Euglena gracilis

scientific article published on 07 February 2019

Trypanosoma brucei brucei: endocytic recycling is important for mouse infectivity

scientific article published on 20 January 2011

Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms

scientific article published on 13 September 2005

Trypanosoma brucei: molecular cloning of homologues of small GTP-binding proteins involved in vesicle trafficking.

scientific article

Trypanosoma brucei: trypanosome-specific endoplasmic reticulum proteins involved in variant surface glycoprotein expression.

scientific article

Ubiquitylation and Developmental Regulation of Invariant Surface Protein Expression in Trypanosomes ⬇️

scientific article published on May 13, 2011

Ubiquitylation is required for degradation of transmembrane surface proteins in trypanosomes

scientific article published on 28 June 2008

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

scientific article published on 03 November 2020

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