List of works - Irene Filippi

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

scientific article published on 8 October 2010

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

scientific article published on 5 July 2017

Carborane-conjugated 2-quinolinecarboxamide ligands of the translocator protein for boron neutron capture therapy.

scientific article published on 18 November 2010

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

scientific article

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

scientific article

Different Expression of Hypoxic and Angiogenic Factors in Human Endometriotic Lesions

scientific article

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

scientific article published on 16 February 2017

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

scientific article

Inhibition of smoothened in breast cancer cells reduces CAXII expression and cell migration

scientific article published on 21 August 2018

Interleukin-1β Affects MDAMB231 Breast Cancer Cell Migration under Hypoxia: Role of HIF-1α and NFκB Transcription Factors

scientific article

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

scientific article published on 26 August 2010

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

scientific article published on 30 August 2011

Protease-activated receptor-2 downregulation is associated to vitiligo lesions

scientific article published on 6 March 2009

Regulation of HMG-CoA reductase expression by hypoxia

scientific article

Rhinovirus 2A is the key protease responsible for instigating the early block to gene expression in infected cells

scientific article published on 07 January 2020

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

scientific article published on January 2011

Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway

scientific article published in December 2014

The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.

scientific article

Thrombin Inhibits IFN-γ Production in Human Peripheral Blood Mononuclear Cells by Promoting a Th2 Profile

scientific article published on 01 November 2006

List of works by Irene Filippi

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

Allergenic proteases cleave the chemokine CX3CL1 directly from the surface of airway epithelium and augment the effect of rhinovirus

Carborane-conjugated 2-quinolinecarboxamide ligands of the translocator protein for boron neutron capture therapy.

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Different Expression of Hypoxic and Angiogenic Factors in Human Endometriotic Lesions

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

Inhibition of smoothened in breast cancer cells reduces CAXII expression and cell migration

Interleukin-1β Affects MDAMB231 Breast Cancer Cell Migration under Hypoxia: Role of HIF-1α and NFκB Transcription Factors

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

Protease-activated receptor-2 downregulation is associated to vitiligo lesions

Regulation of HMG-CoA reductase expression by hypoxia

Rhinovirus 2A is the key protease responsible for instigating the early block to gene expression in infected cells

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

Short-term hypoxia enhances the migratory capability of dendritic cell through HIF-1α and PI3K/Akt pathway

The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.

Thrombin Inhibits IFN-γ Production in Human Peripheral Blood Mononuclear Cells by Promoting a Th2 Profile