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List of works by Mariangela Figini

(177)Lu- labeled MOv18 as compared to (131)I- or (90)Y-labeled MOv18 has the better therapeutic effect in eradication of alpha folate receptor-expressing tumor xenografts.

scientific article

90Y Labeling of monoclonal antibody MOv18 and preclinical validation for radioimmunotherapy of human ovarian carcinomas

scientific article published on 31 May 2005

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing

scientific article published on September 2004

A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.

scientific article published on 20 February 2013

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

scientific article

Anti-PSMA 124I-scFvD2B as a new immuno-PET tool for prostate cancer: preclinical proof of principle

scientific article published on 23 July 2019

Antitumor Effects of a Human Dimeric Antibody Fragment 131I-AFRA-DFM5.3 in a Mouse Model for Ovarian Cancer ⬇️

scientific article published on November 8, 2011

Approaches to implement bispecific antibody treatment of ovarian carcinoma

scientific article published on 01 November 1997

Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4.

scientific article

CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo

scientific article published on 23 November 2011

CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma

scientific article published on August 2004

COVID-19 Vaccination in Health Care Workers in Italy: A Literature Review and a Report from a Comprehensive Cancer Center

scientific article published on 07 May 2022

Characterization of a mouse-human chimeric antibody to a cancer-associated antigen

scientific article published on October 1992

Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma

scientific article published on April 2006

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

scientific article published on March 2015

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

scientific article published on 15 August 2008

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

scientific article published on 06 August 2018

Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen

scientific article published on 09 June 2020

Effect of radiochemical modification on biodistribution of scFvD2B antibody fragment recognising prostate specific membrane antigen

scientific article published on 21 September 2015

Glycolipids carrying Le(y) are preferentially expressed on small-cell lung cancer cells as detected by the monoclonal antibody MLuC1

scientific article published on May 8, 1992

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

scientific article published on 16 May 2011

Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor

scientific article

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

scientific article published on 15 November 2020

In vivo imaging of prostate cancer using an anti-PSMA scFv fragment as a probe.

scientific article published on 21 March 2016

In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)

scientific article

PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models

scientific article (publication date: 2014)

Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection

scientific article

Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction.

scientific article

Redirection of T-cell effector functions for cancer therapy: bispecific antibodies and chimeric antigen receptors

scientific article published on April 2013

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

scientific article published in June 2003

Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor

scientific article published on 2 September 2015

Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility

scientific article

Single-step purification of immunotoxins containing a high ionic charge ribosome inactivating protein clavin by carboxymethyl high-performance membrane chromatography

scientific article published on 01 January 1999

Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo.

scientific article published on February 2015

The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer

scientific article published in October 2006

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