List of works - Barbara Mary Fingleton

A new dress code for MMPs: cleavage optional

scientific article published in January 2010

A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo

scientific article published on February 2007

Abnormal TNF activity in Timp3 −/− mice leads to chronic hepatic inflammation and failure of liver regeneration

scientific article

An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment

scientific article

Apoptotic responses common to cancer and inflammation

scientific article

Cancer in Context: Importance of the Tumor Microenvironment

Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA.

scientific article published on 10 June 2010

Development of a novel murine model of lymphatic metastasis

scientific article published on 12 February 2020

Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis

scientific article

Epithelial interleukin-4 receptor expression promotes colon tumor growth

scientific article

Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth

scientific article published on 12 September 2008

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

scientific article

From tadpoles to TIMPs — making the most of MMPs

article published in 2001

Functional colonography of Min mice using dark lumen dynamic contrast-enhanced MRI.

scientific article published on September 2008

Host-Derived Interleukin-5 Potentiates Lung Metastasis

Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion

scientific article

Host–tumor interactions influencing cancer progression

IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth

scientific article

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

scientific article published in December 2002

Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells

scientific article published on 01 August 2005

Inflammatory proteinase slips into tumor cells

scientific article published on 01 February 2010

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters

scientific article

Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia

scientific article

MMP Inhibitor Clinical Trials – The Past, Present, and Future

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.

scientific article

MMPs as therapeutic targets--still a viable option?

scientific article published on 6 July 2007

Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells.

scientific article

Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis

scientific article

Matrix Metallopeptidase-10/Stromelysin 2

Matrix Metalloproteinases in Cancer

Matrix metalloproteinase inhibitors for cancer therapy: the current situation and future prospects

scholarly article by Barbara Mary Fingleton published 2003 in Expert Opinion on Therapeutic Targets

Matrix metalloproteinase inhibitors for cancer therapy:the current situation and future prospects

scientific article

Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption

scientific article published on January 2000

Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse

scientific article published on December 2008

Matrix metalloproteinases as regulators of inflammatory processes

scientific article

Matrix metalloproteinases as targets for therapy in Kaposi sarcoma

scientific article

Matrix metalloproteinases as valid clinical targets

scientific article published on January 2007

Matrix metalloproteinases: roles in cancer and metastasis

scientific article

Moving targets: Emerging roles for MMPs in cancer progression and metastasis

scientific article

Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis

scientific article published on 09 May 2019

P37. The in vivo impact of host MMP-2 to mammary tumor growth induced osteolysis

Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.

scientific article published on 26 February 2018

Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma

scientific article

Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells.

scientific article

Proteases in Cancer: Significance for Invasion and Metastasis

scholarly article published 2013

Resident stromal cell-derived MMP-9 promotes the growth of colorectal metastases in the liver microenvironment

scientific article published on 01 August 2007

Role of Matrix Metalloproteinases in Tumor Invasion and Metastasis

scholarly article

Role of matrix metalloproteinases in invasion and metastasis: biology, diagnosis and inhibitors

scientific article published on January 1993

Role of matrix metalloproteinases in invasion and metastasis: biology, diagnosis and inhibitors

scientific article

S1658 One of the Good Guys: A Protective Role for Matrix Metalloproteinase-10 in Ulcerative Colitis

scholarly article by Felicitas Koller et al published May 2009 in Gastroenterology

Tcf binding sequence and position determines ?-catenin and Lef-1 responsiveness of MMP-7 promoters

scientific article published on 01 November 2004

The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse.

scientific article

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

scientific article published on May 1999

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

scientific article

Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis

scientific article

List of works by Barbara Mary Fingleton

A new dress code for MMPs: cleavage optional

A rat monoclonal antibody that recognizes pro- and active MMP-7 indicates polarized expression in vivo

Abnormal TNF activity in Timp3 −/− mice leads to chronic hepatic inflammation and failure of liver regeneration

An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment

Apoptotic responses common to cancer and inflammation

Cancer in Context: Importance of the Tumor Microenvironment

Cleavage of E-Cadherin by Matrix Metalloproteinase-7 Promotes Cellular Proliferation in Nontransformed Cell Lines via Activation of RhoA.

Development of a novel murine model of lymphatic metastasis

Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis

Epithelial interleukin-4 receptor expression promotes colon tumor growth

Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

From tadpoles to TIMPs — making the most of MMPs

Functional colonography of Min mice using dark lumen dynamic contrast-enhanced MRI.

Host-Derived Interleukin-5 Potentiates Lung Metastasis

Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion

Host–tumor interactions influencing cancer progression

IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

Increased plasma MMP9 in integrin alpha1-null mice enhances lung metastasis of colon carcinoma cells

Inflammatory proteinase slips into tumor cells

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters

Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia

MMP Inhibitor Clinical Trials – The Past, Present, and Future

MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.

MMPs as therapeutic targets--still a viable option?

Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells.

Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis

Matrix Metallopeptidase-10/Stromelysin 2

Matrix Metalloproteinases in Cancer

Matrix metalloproteinase inhibitors for cancer therapy: the current situation and future prospects

Matrix metalloproteinase inhibitors for cancer therapy:the current situation and future prospects

Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption

Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse

Matrix metalloproteinases as regulators of inflammatory processes

Matrix metalloproteinases as targets for therapy in Kaposi sarcoma

Matrix metalloproteinases as valid clinical targets

Matrix metalloproteinases: roles in cancer and metastasis

Moving targets: Emerging roles for MMPs in cancer progression and metastasis

Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis

P37. The in vivo impact of host MMP-2 to mammary tumor growth induced osteolysis

Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.

Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma

Proliferative effects of apical, but not basal, matrix metalloproteinase-7 activity in polarized MDCK cells.

Proteases in Cancer: Significance for Invasion and Metastasis

Resident stromal cell-derived MMP-9 promotes the growth of colorectal metastases in the liver microenvironment

Role of Matrix Metalloproteinases in Tumor Invasion and Metastasis

Role of matrix metalloproteinases in invasion and metastasis: biology, diagnosis and inhibitors

Role of matrix metalloproteinases in invasion and metastasis: biology, diagnosis and inhibitors

S1658 One of the Good Guys: A Protective Role for Matrix Metalloproteinase-10 in Ulcerative Colitis

Tcf binding sequence and position determines ?-catenin and Lef-1 responsiveness of MMP-7 promoters

The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse.

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis