List of works - Neil Ashley

Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1

scientific article published on 16 January 2019

Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene

scientific article

Colonic epithelial cell diversity in health and inflammatory bowel disease

scientific article published on 27 February 2019

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances

scientific article published on 03 May 2007

Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations

scientific article published on 13 October 2009

Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining.

scientific article

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

scientific article published on 14 December 2016

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

scientific article published in February 2018

Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention

scientific article published on 12 July 2005

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

scientific article published on September 2017

Liver mtDNA content increases during development: A comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion

article

Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays

scientific article published on 7 July 2014

Relationship between genome and epigenome--challenges and requirements for future research

scientific article published on 18 June 2014

Separation of cancer cells from white blood cells by pinched flow fractionation

scientific article published on 29 October 2015

Sequencing Metrics of Human Genomes Extracted from Single Cancer Cells Individually Isolated in a Valveless Microfluidic Device

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia

scientific article published on 01 December 2019

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

scientific article published on 3 May 2016

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

scientific article

Spatiotemporal analysis of human intestinal development at single-cell resolution

scientific article published on 04 January 2021

Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors

scientific article published on 18 July 2013

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

scientific article published on 27 September 2018

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

scientific article

List of works by Neil Ashley

Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1

Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene

Colonic epithelial cell diversity in health and inflammatory bowel disease

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances

Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations

Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining.

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Liver mtDNA content increases during development: A comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion

Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays

Relationship between genome and epigenome--challenges and requirements for future research

Separation of cancer cells from white blood cells by pinched flow fractionation

Sequencing Metrics of Human Genomes Extracted from Single Cancer Cells Individually Isolated in a Valveless Microfluidic Device

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

Spatiotemporal analysis of human intestinal development at single-cell resolution

Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number