List of works by Julio Aguirre-Ghiso

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

scientific journal article

A local view of cancer

scientific article published on March 2012

A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy

scientific article published on 13 December 2021

Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties

scientific article

Bone marrow NG2<sup>+</sup>/Nestin<sup>+</sup> mesenchymal stem cells drive DTC dormancy <i>via</i> TGFβ2

scientific article published on 11 March 2021

Combined Inhibition of Epidermal Growth Factor Receptor and Cyclooxygenase-2 as a Novel Approach to Enhance Radiotherapy.

scientific article published on October 2011

Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence

scientific article published on 07 July 2009

Dormancy of metastatic melanoma

scientific article

Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer

scientific article

Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival.

scientific article published on May 2008

ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).

scientific article published on April 2003

Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

scientific article published on February 2006

Green fluorescent protein tagging of extracellular signal-regulated kinase and p38 pathways reveals novel dynamics of pathway activation during primary and metastatic growth

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Immortalized mammary epithelial cells overexpressing protein kinase C gamma acquire a malignant phenotype and become tumorigenic in vivo.

scientific article published in August 2003

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

scientific article published on 07 January 2014

Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesis

scientific article published on 15 September 2009

Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy

scientific article published on 03 February 2009

Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation

scientific article

Integration of microenvironmental and stress signaling antagonizes colorectal cancer progression

scientific article

Mechanisms of disseminated cancer cell dormancy: an awakening field

scientific article

Metastasis awakening: targeting dormant cancer.

scientific article published in March 2013

Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.

scientific article published on 8 February 2005

On the theory of tumor self-seeding: implications for metastasis progression in humans

scientific article

Oropharyngeal cancer biology and treatment: insights from messenger RNA sequence analysis and transoral robotic surgery

scientific article published on March 2012

PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment

scientific article

Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy

scientific article published on 07 February 2012

RalA mediates v-Src, v-Ras, and v-Raf regulation of CD44 and fibronectin expression in NIH3T3 fibroblasts

scientific article published on May 2001

RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases

scientific article

Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

scientific article published on 19 November 2012

Regulation of tumor cell dormancy by tissue microenvironments and autophagy.

scientific article published on January 2013

Ribonomic and short hairpin RNA gene silencing methods to explore functional gene programs associated with tumor growth arrest

scientific article

Stress signaling and the shaping of the mammary tissue in development and cancer

scientific article

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling.

scientific article published on 27 October 2013

The problem of cancer dormancy: understanding the basic mechanisms and identifying therapeutic opportunities.

scientific article published on 15 August 2006

Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

scientific article published on April 2001

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

scientific article

p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.

scientific article published on 24 May 2011