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List of works by Lionel Apetoh

5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity

scientific article published on 13 April 2010

A novel dendritic cell subset involved in tumor immunosurveillance

scientific article published on 29 January 2006

AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.

scientific article published on July 2015

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen.

scientific article published on 5 August 2016

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

scientific article (publication date: October 2009)

An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets

scientific article published on 01 November 2020

Anticancer effects of the microbiota: how the microbiome shapes the development of IL-9-producing T cells

scientific article published on 06 July 2020

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer

scientific article published on 17 April 2019

Bleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cells

scientific article (publication date: 2013)

CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer

scientific article published on October 2008

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

scientific article published on July 2016

Calreticulin exposure dictates the immunogenicity of cancer cell death

scientific article

Can Immunogenic Chemotherapies Relieve Cancer Cell Resistance to Immune Checkpoint Inhibitors?

scientific article

Cancer chemotherapy: not only a direct cytotoxic effect, but also an adjuvant for antitumor immunity

scientific article published on 28 March 2008

Cancer is not just a disease of a tissue: It is a host disease

scientific article published on 16 April 2008

Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation

scientific article published on 24 February 2015

Cell-Intrinsic Roles for Autophagy in Modulating CD4 T Cell Functions.

scientific article published on 9 May 2018

Cell-death-associated molecular patterns as determinants of cancer immunogenicity

scientific article published on 20 March 2013

Chemotherapy and immunomodulation: from immunogenic chemotherapies to novel therapeutic strategies

scientific article published in April 2013

Chemotherapy and radiotherapy: cryptic anticancer vaccines

scientific article published on 18 April 2010

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1.

scientific article published on 29 October 2015

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

scientific article published on 2 December 2012

Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance

scientific article published on 14 October 2019

Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?

scientific article published on 28 April 2015

Consensus guidelines for the detection of immunogenic cell death

scientific article published on October 2014

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

scientific article

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Controversies on the role of Th17 in cancer: a TGF-β-dependent immunosuppressive activity?

scientific article published on 17 October 2012

Correction: Corrigendum: The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

scientific article published in December 2015

Correction: Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway

scientific article published on 20 April 2017

Crizotinib-induced immunogenic cell death in non-small cell lung cancer

scientific article published on 02 April 2019

Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth

scientific article published on 6 September 2012

Danger signals: Chemotherapy enhancers?

scientific article

Desirable cell death during anticancer chemotherapy

scientific article published on October 2010

Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?

scientific article published on 25 January 2016

Ecto-calreticulin in immunogenic chemotherapy

scientific article published on December 2007

Enhancing the anticancer effects of 5-fluorouracil: current challenges and future perspectives

scientific article

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

scientific article

FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial

scientific article

Fas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions

scientific article published on 02 July 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

HSP70 is a negative regulator of NLRP3 inflammasome activation

scientific article published on 15 March 2019

Harnessing dendritic cells in cancer

scientific article published on 03 February 2011

Human FOXP3 and cancer

scientific article published on 24 May 2010

Human ectonucleotidase-expressing CD25(high) Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions

scientific article published on 6 July 2015

IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production.

scientific article published on 25 September 2017

IRF8-dependent molecular complexes control the Th9 transcriptional program.

scientific article published on 12 December 2017

Immune effects of 5-fluorouracil: Ambivalence matters

scientific article published on March 2013

Immunogenic cancer cell death: a key-lock paradigm

scientific article published on 23 June 2008

Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.

scientific article published on March 2007

Immunogenic death of colon cancer cells treated with oxaliplatin

scientific article published on 2 November 2009

Immunogenicity of anthracyclines: moving towards more personalized medicine

scientific article published on 18 March 2008

Immunological aspects of cancer chemotherapy

scientific article published on January 2008

Immunotherapeutic properties of chemotherapy

scientific article

In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival

scientific article published on 25 March 2011

Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27.

scientific article published on 3 September 2011

Inhibition of colon cancer growth by docosahexaenoic acid involves autocrine production of TNFα.

scientific article published on 8 February 2016

La calréticuline détermine l’immunogénicité de la chimiothérapie et de la radiothérapie antitumorales

scientific article published in March 2007

Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic

scientific article published on September 2007

Links between innate and cognate tumor immunity

scientific article published on 15 February 2007

Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells

scientific article

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

scientific article

Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation.

scientific article published on 29 April 2013

Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors

scientific article published on 19 July 2020

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

scientific article

Molecular characteristics of immunogenic cancer cell death.

scientific article

Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference

scientific article published on 22 May 2007

Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies

scientific article published on June 2008

Molecular pathways in the induction of interleukin-27-driven regulatory type 1 cells.

scientific article

PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer. ⬇️

scientific article published on 15 March 2018

Pathologic Complete Response to Neoadjuvant Chemotherapy of Breast Carcinoma Is Associated with the Disappearance of Tumor-Infiltrating Foxp3+ Regulatory T Cells

scientific article published on 27 March 2008

Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway

scientific article

Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients

scientific article

Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites

scientific article published on 18 July 2016

Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen

scientific article

Radiotherapy and immunogenic cell death

scientific article

Rationale for stimulator of interferon genes-targeted cancer immunotherapy

scientific article published on 17 February 2017

Relation between bevacizumab dose intensity and high-grade glioma survival: a retrospective study in two large cohorts.

scientific article

Restoration of Antitumor Immunity Through Selective Inhibition of Myeloid Derived Suppressor Cells by Anticancer Therapies ⬇️

scientific article published on July 1, 2011

Role of myeloid-derived suppressor cells in tumor immunotherapy

scientific article published on January 2012

SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth

scientific article published on 25 April 2013

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

scientific article published in Nature Communications

Selective autophagy restricts IL-9 secretion from TH9 cells: relevance in cancer growth

scientific article published on 12 December 2017

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

scientific article published on 15 September 2017

Signalling strength determines proapoptotic functions of STING.

scientific article

Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation

scientific article published on April 2017

Socs3 induction by PPARγ restrains cancer-promoting inflammation.

scientific article published on July 2013

Stat3 and Gfi-1 Transcription Factors Control Th17 Cell Immunosuppressive Activity via the Regulation of Ectonucleotidase Expression

scientific article published on 08 March 2012

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome.

scientific article published on 11 September 2015

T-bet expression in intratumoral lymphoid structures after neoadjuvant trastuzumab plus docetaxel for HER2-overexpressing breast carcinoma predicts survival

scientific article

TH9 cells in anti-tumor immunity

scientific article

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

scientific article published on 30 May 2011

Th9 cells: a new population of helper T cells

scientific article published on April 2016

Th9 cells: a novel CD4 T-cell subset in the immune war against cancer.

scientific article

The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response

scientific article published on 20 June 2019

The anticancer immune response: indispensable for therapeutic success?

scientific article published on June 2008

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

scientific article

The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.

scientific article published in May 2008

The immunosuppressive enzyme IL4I1 promotes FoxP3(+) regulatory T lymphocyte differentiation.

scientific article published on 17 April 2015

The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

scientific article published on December 2007

The interplay between the immune system and chemotherapy: emerging methods for optimizing therapy

scientific article published on 05 December 2013

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

scientific article

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

scientific journal article

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells

scientific article

The tumor microenvironment impairs Th1 IFNγ secretion through alternative splicing modifications of Irf1 pre-mRNA

scientific article published on 08 January 2021

Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.

scientific article

Trial Watch: Adoptively transferred cells for anticancer immunotherapy

scientific article published on 11 August 2017

Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity

scientific article published on 19 January 2010

Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients

scientific article published on 3 June 2015

Type 1 regulatory T cells (Tr1) in autoimmunity

scientific article

Witch hunt against tumor cells enhanced by dendritic cells

scientific article published on September 2009

[Immunological aspects of anticancer chemotherapy]

scientific article published on 01 October 2008

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