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List of works by Stefano Manfredini

2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase

scientific article

3,4-Bismethylenecyclopentanone ethylene ketal: A useful diene for[6.5]ring systems: Application to a formal synthesis of gibberellic acid

scientific article published in January 1989

5‘-Phosphoramidates and 5‘-Diphosphates of 2‘-O-Allyl-β-d-arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase

scientific article published on 01 August 1999

7-deazainosine derivatives: synthesis and characterization of 7- and 7,8-substituted pyrrolo [2,3-d]pyrimidine ribonucleosides

scientific article published in May 2008

A Multi-Target Approach toward the Development of Novel Candidates for Antidermatophytic Activity: Ultrastructural Evidence on α-Bisabolol-Treated Microsporum gypseum.

scientific article published on 26 June 2015

A New Approach to UV Protection by Direct Surface Functionalization of TiO2 with the Antioxidant Polyphenol Dihydroxyphenyl Benzimidazole Carboxylic Acid

scientific article published on 28 January 2020

A PLE-based resolution of cocaine, pseudococaine, and 6- and 7-methoxylated cocaine analogues

scientific article published in February 1996

A non-invasive method for the in vivo determination of skin antioxidant capacity (IAC-S).

scientific article published in November 2006

Activity and stability studies of verbascoside, a novel antioxidant, in dermo-cosmetic and pharmaceutical topical formulations.

scientific article

Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase

scientific article published on 01 November 2005

Antidermatophytic Action of Resorcinol Derivatives: Ultrastructural Evidence of the Activity of Phenylethyl Resorcinol against Microsporum gypseum

scientific article published on 30 September 2016

Antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.

scientific article published in July 2011

Antioxidant effect of FeAOX-6 on free radical species produced during iron catalyzed breakdown of tert-butyl hydroperoxide

scientific article published in February 2006

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs.

scientific article published on 19 December 2004

Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity

scientific article published on 02 July 2018

Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-beta-D-glucopyranosides.

scientific article

Carnitine conjugate of nipecotic acid: a new example of dual prodrug.

scientific article published on 31 August 2009

ChemInform Abstract: Design, Synthesis and Enzymatic Activity of Highly Selective Human Mitochondrial Thymidine Kinase Inhibitors

Chemical Composition and Anti-Candida Activity of Mentha suaveolens Ehrh. Essential Oils Obtained by Different Distillation Processes

scientific article published in 2023

Chemical Composition and Biological Activity of Five Essential Oils from the Ecuadorian Amazon Rain Forest

article

Cholinergic agents structurally related to furtrethonium. 2. Synthesis and antimuscarinic activity of a series of N-[5-[(1'-substituted-acetoxy) methyl]-2-furfuryl]dialkylamines

scientific article published on 01 December 1994

Combination of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate for the treatment of inflammatory lung diseases: An in vitro study

scientific article published on 30 April 2018

Comparative Study of SPA Mud from "Bacino Idrominerario Omogeneo dei Colli Euganei (B.I.O.C.E.)-Italy" and Industrially Optimized Mud for Skin Applications

scientific article published on 26 May 2020

Control of Erwinia amylovora Growth by Moringa oleifera Leaf Extracts: In Vitro and in Planta Effects

scientific article published in 2022

Design and synthesis of phosphonoacetic acid (PPA) ester and amide bioisosters of ribofuranosylnucleoside diphosphates as potential ribonucleotide reductase inhibitors and evaluation of their enzyme inhibitory, cytostatic and antiviral activity

scientific article published on July 2003

Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones.

scientific article published on 30 April 2016

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity.

scientific article published on January 2002

Design, synthesis and anti flaviviridae activity of N(6)-, 5',3'-O- and 5',2'-O-substituted adenine nucleoside analogs

scientific article

Design, synthesis and antiproliferative activity of methyl 4-Iodo-1-β-D-ribofuranosyl-pyrazole-3-carboxylate and related compounds

scientific article published in 1996

Design, synthesis and binding at cloned muscarinic receptors of N -[5-(1′-substituted-acetoxymethyl)-3-oxadiazolyl] and N -[4-(1′-substituted-acetoxymethyl)-2-dioxolanyl] dialkyl amines

scientific article published in July 2000

Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties.

scientific article

Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.

scientific article published in May 2001

Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors

scientific article published on 15 July 2015

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules.

scientific article published in October 2004

Design, synthesis and in vivo activity of 9-(S)-dihydroerythromycin derivatives as potent anti-inflammatory agents

scientific article published on 18 September 2006

Design, synthesis, and antioxidant activity of FeAOX-6, a novel agent deriving from a molecular combination of the chromanyl and polyisoprenyl moieties

scientific article

Design, synthesis, and antioxidant potency of novel alpha-tocopherol analogues in isolated membranes and intact cells

scientific article

Development and characterization of biodegradable nanospheres as delivery systems of anti-ischemic adenosine derivatives

scientific article published in April 2005

Effects of Flavonoids and Phenols from Moringa oleifera Leaf Extracts on Biofilm Processes in Xanthomonas campestris pv. campestris ⬇️

scientific article published on 30 March 2023

Effects of new combinative antioxidant FeAOX-6 and alpha-tocotrienol on macrophage atherogenesis-related functions

scientific article

Evaluation of antiradical activity of different cocoa and chocolate products: relation with lipid and protein composition.

scientific article published on 16 January 2014

Expert Systems for Predicting the Bioavailability of Sun Filters in Cosmetic Products, Software vs. Expert Formulator: The Benzophenone-3 Case

scientific article published in 2022

Facile synthesis of 2-nitroalkanols by tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones

article

First Report of Pinnatoxin-G (PnTX-G) in a Marine–Coastal Area of the Adriatic Sea Associated with the Presence of the Dinoflagellate Vulcanodinium rugosum

scientific article published in 2024

Formulation and Characterization of Native and Crosslinked Hyaluronic Acid Microspheres for Dermal Delivery of Sodium Ascorbyl Phosphate: A Comparative Study

scientific article published on 01 December 2018

Frataxin mRNA isoforms in FRDA patients and normal subjects: effect of tocotrienol supplementation

scientific article published on 23 September 2013

Geiparvarin analogues. 2. Synthesis and cytostatic activity of 5-(4-arylbutadienyl)-3(2H)-furanones and of N-substituted 3-(4-oxo-2-furanyl)-2-buten-2-yl carbamates

scientific article published on 01 November 1991

Geiparvarin analogues. 3. Synthesis and cytostatic activity of 3(2H)-furanone and 4,5-dihydro-3(2H)-furanone congeners of geiparvarin, containing a geraniol-like fragment in the side chain

scientific article published on 01 May 1992

Geiparvarin analogues. 4. Synthesis and cytostatic activity of geiparvarin analogues bearing a carbamate moiety or a furocoumarin fragment on the alkenyl side chain

scientific article published on July 1994

Herbal extracts, lichens and biomolecules as natural photo-protection alternatives to synthetic UV filters. A systematic review.

scientific article published on 15 September 2016

Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property

scientific article published on 01 December 2006

In vitro characterization of physico-chemical properties, cytotoxicity, bioactivity of urea-crosslinked hyaluronic acid and sodium ascorbyl phosphate nasal powder formulation

scientific article published on 16 January 2019

In vitro neuroprotection by novel antioxidants in guinea-pig urinary bladder subjected to anoxia-glucopenia/reperfusion damage

scientific article published on 20 November 2004

Iranian Medicinal Plants: From Ethnomedicine to Actual Studies

scientific article published on 26 February 2020

Microbial Biosurfactants as Key Multifunctional Ingredients for Sustainable Cosmetics

scientific article published in 2020

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water ⬇️

scientific article published on July 7, 2013

Moringa oleifera Leaf Extracts as Multifunctional Ingredients for "Natural and Organic" Sunscreens and Photoprotective Preparations

scientific article published on 15 March 2018

Nanoparticle formulation may affect the stabilization of an antiischemic prodrug.

scientific article published on 14 November 2005

Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer

scientific article

Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study

scientific article published on 30 November 2017

Novel antioxidant agents deriving from molecular combinations of vitamins C and E analogues: 3,4-dihydroxy-5(R)

scientific article published on 01 December 2000

Novel molecular combination deriving from natural aminoacids and polyphenols: Design, synthesis and free-radical scavenging activities

scientific article published on 17 February 2012

Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity

scientific article published on 2 February 2007

Nucleic acid related compounds. 65. New syntheses of 1-(beta-D-arabinofuranosyl)-5(E)-(2-iodovinyl)uracil (IVAraU) from vinylsilane precursors. Radioiodine uptake as a marker for thymidine kinase positive herpes viral infections

scientific article

Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features

scientific article

Oxidative Stress in Autistic Children Alters Erythrocyte Shape in the Absence of Quantitative Protein Alterations and of Loss of Membrane Phospholipid Asymmetry

scientific article published on 11 November 2018

Peptide T-araC conjugates: solid-phase synthesis and biological activity of N 4 -(acylpeptidyl)-araC

scientific article published on 01 March 2000

Phloridzin derivatives inhibiting pro-inflammatory cytokine expression in human cystic fibrosis IB3-1 cells.

scientific article published on 22 July 2015

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress

scientific article published on 06 August 2010

Prodrugs of Ara-CMP and Ara-AMP with a S-acyl-2-thioethyl (SATE) biolabile phosphate protecting group: synthesis and biological evaluation

scientific article published on April 1999

Progress in drug delivery to the central nervous system by the prodrug approach.

scientific article published on May 2008

Protective effects of Fe-Aox29, a novel antioxidant derived from a molecular combination of Idebenone and vitamin E, in immortalized fibroblasts and fibroblasts from patients with Friedreich Ataxia.

scientific article published on 3 May 2007

Pyrazole related nucleosides 5. Synthesis and biological activity of 2'-deoxy-2',3'-dideoxy- and acyclo-analogues of 4-iodo-1-beta-D-ribofuranosyl-3-carboxymethyl pyrazole (IPCAR).

scientific article

Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides

scientific article (publication date: 6 March 1992)

Pyrazolo-triazoles as light activable DNA cleaving agents

scientific article

Pyrazolo[3,4-c]isothiazole and isothiazolo[4,3-d]isoxazole derivatives as antifungal agents

scientific article published on 09 March 2011

Pyrazolo[4,3-d]pyrimidine nucleosides. Synthesis and antiviral activity of 1-beta-D-ribofuranosyl-3-methyl-6-substituted-7H-pyrazolo[4,3-d]pyr imi din-7-ones

scientific article published on August 1984

Quorum sensing inhibition activity of garlic extract and p-coumaric acid

scientific article published on 24 July 2009

Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives.

scientific article

Retinoic acid conjugates as potential antitumor agents: synthesis and biological activity of conjugates with Ara-A, Ara-C, 3(2H)-furanone, and aniline mustard moieties

scientific article published on 01 November 1997

Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

scientific article published on 21 September 2020

Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration

scientific article published on 24 March 2020

Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents

scientific article published on 06 May 2020

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

scientific article published on 07 April 2020

Synthesis and Characterization of New Multifunctional Self-Boosted Filters for UV Protection: ZnO Complex with Dihydroxyphenyl Benzimidazole Carboxylic Acid

scientific article published on 12 December 2019

Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogs of pyrrolo[1,4]benzodiazepines (PBDs)

scientific article published in 1993

Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogues of pyrrolo[1,4][2,1-c]benzodiazepines

scientific article published on 01 December 1994

Synthesis and biological evaluation of a series of substituted pyrazolo[3,4-d]-1,2,3-triazoles and pyrazolo[3,4-d]oxazoles

scientific article published on September 1998

Synthesis and biological evaluation of pro-drugs of GW196771, a potent glycine antagonist acting at the NMDA receptor.

scientific article published in May 2005

Synthesis and cytotoxic activity of 6-vinyl- and 6-ethynyluridine and 8-vinyl-and 8-ethynyladenosine

scientific article published on 01 January 1995

Synthesis and in vitro stability of nucleoside 5'-phosphonate derivatives

scientific article published on 15 May 2012

Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex.

scientific article

Synthesis and study of 5'-ester prodrugs of N6-cyclopentyladenosine, a selective A1 receptor agonist

scientific article published in April 2001

Synthesis, Cytostatic Activity and Inhibition of Ribonucleotide Reductase by 5′-Phosphoramidates and 5′-Diphosphates, of 2′-O-Allyl-arabinofuranosyl Nucleosides

scientific article published on 01 April 1999

Synthesis, antioxidant and antimicrobial activity of a new phloridzin derivative for dermo-cosmetic applications.

scientific article published on 7 November 2012

Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1, 4]benzodiazepine and minor-groove-binding oligopyrrole carriers

scientific article

Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β Species

scientific article

Synthetic approaches to a mononucleotide prodrug of cytarabine

scientific article published in January 2005

Synthetic studies toward C-glucosidic ellagitannins: a biomimetic total synthesis of 5-O-desgalloylepipunicacortein A

scientific article published on 15 June 2012

Synthèse de quelques dérivés isoxazoliques analogues des rétinoides. Effects biologiques vis-à-vis des cellules tumorales

The Antioxidants and Pro-Antioxidants Network: An Overview

scientific article

Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate

scientific article published on January 2004

Up-Cycling of Olea europaea L. Ancient Cultivars Side Products: Study of a Combined Cosmetic–Food Supplement Treatment Based on Leaves and Olive Mill Wastewater Extracts

scientific article published in 2023

Vitamin C and 6-amino-vitamin C conjugates of diclofenac: synthesis and evaluation.

scientific article published on 30 December 2004

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