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List of works by Simon J Gibbons

A gamma variate model that includes stretched exponential is a better fit for gastric emptying data from mice

scientific article

A little humour relaxes the gallbladder.

scientific article published on September 2010

A simple automated approach to measure mouse whole gut transit

scientific article published on 30 September 2020

A stochastic multi-scale model of electrical function in normal and depleted ICC networks.

scientific article published on 12 August 2011

AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

scientific article published on 01 June 1995

Ano1 as a regulator of proliferation ⬇️

scientific article published on September 22, 2011

Apoptotic cell death of human interstitial cells of Cajal.

scientific article published on 16 September 2008

Association of low numbers of CD206-positive cells with loss of ICC in the gastric body of patients with diabetic gastroparesis

scientific article

Calcium influx and neurodegeneration

scientific article published on May 1993

Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism

scientific article

Carbon monoxide reverses diabetic gastroparesis in NOD mice.

scientific article published on 8 April 2010

Cellular automaton model for simulating tissue-specific intestinal electrophysiological activity.

scientific article

Cellular pathogenesis of diabetic gastroenteropathy.

scientific article

Changes in interstitial cells of cajal with age in the human stomach and colon.

scientific article

Changes in nitrergic and tachykininergic pathways in rat proximal colon in response to chronic treatment with otilonium bromide.

scientific article published on 30 April 2015

Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal

scientific article published on 30 January 2014

Computer aided classification of cell nuclei in the gastrointestinal tract by volume and principal axis

scientific article

Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine

scientific article

Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits: histopathological correlation

scientific article

Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells

scientific article published on 01 November 1994

Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation.

scientific article published on 3 November 2005

Determination of gastric emptying in nonobese diabetic mice

scientific article published on 20 September 2007

Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves

scientific article

EAVK segment "c" sequence confers Ca2+-dependent changes to the kinetics of full-length human Ano1.

scientific article published on 23 March 2017

Effect of mibefradil on sodium and calcium currents

scientific article

Expression and trans-synaptic regulation of P2x4 and P2z receptors for extracellular ATP in parotid acinar cells. Effects of parasympathetic denervation

scientific article published on 01 October 1998

Expression of RAD21 immunoreactivity in myenteric neurons of the human and mouse small intestine

scientific article published on 01 August 2018

Extracellular Cl- regulates electrical slow waves and setting of smooth muscle membrane potential by interstitial cells of Cajal in mouse jejunum.

scientific article published on 3 October 2017

Gastrointestinal hypomotility with loss of enteric nicotinic acetylcholine receptors: active immunization model in mice.

scientific article published on 17 October 2012

Glutamate receptor agonists stimulate diverse calcium responses in different types of cultured rat cortical glial cells

scientific article

Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis.

scientific article published on 11 September 2008

Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, Nav1.5.

scientific article published on 10 March 2011

Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6)

scientific article

Identification of intrinsic primary afferent neurons in mouse jejunum

scientific article published on 28 September 2020

Immunoreactivity for Ano1 detects depletion of Kit-positive interstitial cells of Cajal in patients with slow transit constipation.

scientific article

Increase in [Ca2+]i by CCh in adult rat sympathetic neurons are not dependent on intracellular Ca2+ pools

scientific article published on April 1995

Inhibition of a fast inwardly rectifying potassium conductance by barbiturates

scientific article published on June 1996

Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.

scientific article

Irritable bowel syndrome (IBS) patients have SCN5A channelopathies that lead to decreased NaV1.5 current and mechanosensitivity.

scientific article published on 22 November 2017

Kit signaling is required for development of coordinated motility patterns in zebrafish gastrointestinal tract

scientific article published on 8 January 2013

Kit-like immunoreactivity in the zebrafish gastrointestinal tract reveals putative ICC

scientific article published on 01 March 2007

Kit/stem cell factor receptor-induced phosphatidylinositol 3'-kinase signalling is not required for normal development and function of interstitial cells of Cajal in mouse gastrointestinal tract

scientific article

Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.

scientific article

Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture

scientific article published on 9 October 2002

Macrophages in diabetic gastroparesis--the missing link?

scientific article published on 28 August 2014

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways

scientific article

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons

scientific article published on 31 January 2019

Muscularis macrophages establish cell-to-cell contacts with telocytes/PDGFRα-positive cells and smooth muscle cells in the human and mouse gastrointestinal tract

scientific article published on 05 October 2020

Not just there to fill space: profound observations on interstitial cells of Cajal in the gastric fundus

scientific article published on 01 April 2018

Numerical metrics for automated quantification of interstitial cell of Cajal network structural properties

scientific article published on 26 June 2013

P2X(7) receptors in rat parotid acinar cells: formation of large pores

scientific article published in August 2001

Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.

scientific article published on 9 April 2015

Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans.

scientific article published on June 2012

Potassium outward currents in freshly dissociated rabbit corpus cavernosum myocytes

scientific article published on September 2001

Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis

scientific article published on 04 September 2019

Salivary gland P2 nucleotide receptors.

scientific article

Slow-wave coupling across a gastroduodenal anastomosis as a mechanism for postsurgical gastric dysfunction: evidence for a "gastrointestinal aberrant pathway"

scientific article published on 06 June 2019

Sodium current in human intestinal interstitial cells of Cajal

scientific article published on 31 July 2003

Species dependent expression of intestinal smooth muscle mechanosensitive sodium channels

scientific article published in February 2007

T-type Ca(2+) channel modulation by otilonium bromide.

scientific article

The Kv2.2 alpha subunit contributes to delayed rectifier K(+) currents in myocytes from rabbit corpus cavernosum.

scientific article published in November 2002

The alpha1H Ca2+ channel subunit is expressed in mouse jejunal interstitial cells of Cajal and myocytes

scientific article

The properties of intracellular calcium stores in cultured rat cerebellar neurons

scientific article published in December 1991

The role of carbon monoxide in the gastrointestinal tract.

scientific article published on 6 February 2004

Tissue-specific mathematical models of slow wave entrainment in wild-type and 5-HT(2B) knockout mice with altered interstitial cells of Cajal networks.

scientific article published in May 2010

Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels

scientific article published on August 1994

alpha(1C) (Ca(V)1.2) L-type calcium channel mediates mechanosensitive calcium regulation

scientific article published on September 2002

microRNA overexpression in slow transit constipation leads to reduced NaV1.5 current and altered smooth muscle contractility

scientific article published on 22 November 2019

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