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List of works by Boris Hinz

A Novel Method of Dynamic Culture Surface Expansion Improves Mesenchymal Stem Cell Proliferation and Phenotype

article

A key role for NOX4 in epithelial cell death during development of lung fibrosis.

scientific article

A new lock-step mechanism of matrix remodelling based on subcellular contractile events

scientific article published on 27 April 2010

Activin A in Inflammation, Tissue Repair, and Fibrosis: Possible Role as Inflammatory and Fibrotic Mediator of Uterine Fibroid Development and Growth

scientific article published on 3 November 2017

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts.

scientific article

Author Correction: Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix

scientific article published on 20 May 2019

Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells

scientific article published in November 2005

Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β

scientific article published on 15 January 2019

Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity

scientific article

Cellular, structural and functional cardiac remodelling following pressure overload and unloading.

scientific article published on 23 April 2016

Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology

scientific article published on 11 October 2016

Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity

scientific article published on 01 May 2006

Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research

scientific article published on October 2016

Culture of primary bovine chondrocytes on a continuously expanding surface inhibits dedifferentiation

scientific article

Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition

scientific article published on 4 September 2013

Discoidin Domain Receptor 1 Mediates Myosin-Dependent Collagen Contraction

scientific article published in February 2017

Does Breathing Amplify Fibrosis?

scientific article

Dynamic expansion culture for mesenchymal stem cells

scientific article published on 01 January 2011

Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix

scientific article published on 23 April 2019

Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases

scientific article published on 02 December 2019

Experimental Right Ventricular Hypertension Induces Regional β1-Integrin-Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling.

scientific article

Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells.

scientific article published on 28 May 2015

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

scientific article published on 23 September 2007

Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

scientific article

Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives

scientific article

Fibrotic microtissue array to predict anti-fibrosis drug efficacy.

scientific article published on 25 May 2018

Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix

scientific article published on 2 July 2015

Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers

scientific article

Formation and function of the myofibroblast during tissue repair

scientific article published on March 2007

Grab, stick, pull and digest: the functional diversity of actin-associated matrix-adhesion structures. Workshop on Invadopodia, Podosomes and Focal Adhesions in Tissue Invasion

scientific article published on 18 January 2008

Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation

scientific article published on 12 January 2016

Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation

scientific article published in July 2015

Hypoxia impairs skin myofibroblast differentiation and function

scientific article published on 5 August 2010

Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H.

scientific article

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

scientific article

Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship

scientific article

Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction

scientific article

Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro

scientific article published on 27 September 2005

Isoform-specific regulation of the actin-organizing protein palladin during TGF-beta1-induced myofibroblast differentiation

scientific article (publication date: November 2006)

It has to be the αv: myofibroblast integrins activate latent TGF-β1.

scientific article published in December 2013

Kindlin-2 Mediates Mechanical Activation of Cardiac Myofibroblasts

scientific article published on 17 December 2020

Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge

scientific article published on 15 June 2017

Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.

scientific article

Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior

scientific article

Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission

scientific article

Matrix mechanics and regulation of the fibroblast phenotype

scientific article published on October 1, 2013

Mechanical aspects of lung fibrosis: a spotlight on the myofibroblast

scientific article published on 01 July 2012

Mechanical control of cardiac myofibroblasts

scientific article

Mechanical induction of gene expression in connective tissue cells

scientific article published on January 2010

Mechanisms of force generation and transmission by myofibroblasts

scientific article published on October 2003

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells.

scientific article

Myofibroblast communication is controlled by intercellular mechanical coupling

scientific article published on 30 September 2008

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

scientific article

Myofibroblast development is characterized by specific cell-cell adherens junctions.

scientific article published on 07 July 2004

Myofibroblasts

scientific article published on 17 July 2015

Myofibroblasts and mechano-regulation of connective tissue remodelling

scientific article (publication date: May 2002)

Myofibroblasts work best under stress

scientific article published on 12 May 2008

NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression.

scientific article

Nonactivated versus thrombin-activated platelets on wound healing and fibroblast-to-myofibroblast differentiation in vivo and in vitro

scientific article published on 01 January 2012

Novel Differences in Gene Expression and Functional Capabilities of Myofibroblast Populations in Idiopathic Pulmonary Fibrosis

article

Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants

scientific article published on 2 April 2015

Plasma fibronectin stabilizes Borrelia burgdorferi-endothelial interactions under vascular shear stress by a catch-bond mechanism

scientific article

Possible involvement of inflammatory/reparative processes in the development of uterine fibroids

scientific article published on 27 November 2015

Preclinical Models of Wound Healing: Is Man the Model? Proceedings of the Wound Healing Society Symposium

scientific article published on February 2013

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.

scientific article

Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1-7)

scientific article published on 30 August 2021

Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins.

scientific article published on 29 September 2013

Quantifying Lamella Dynamics of Cultured Cells by SACED, a New Computer-Assisted Motion Analysis

article

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

scientific article

Regulation of myofibroblast activities: calcium pulls some strings behind the scene

scientific article published on 06 May 2010

Signs of stress on soft surfaces : A commentary on: Cui, Y., F.M. Hameed, B. Yang, K. Lee, C.Q. Pan, S. Park, and M. Sheetz. 2015. Cyclic stretching of soft substrates induces spreading and growth. Nat Commun. 6:6333.

scientific article published on 16 August 2015

Strategies to overcome the hurdles to treat fibrosis, a major unmet clinical need

scientific article published on 24 June 2016

Temporal and Molecular Analyses of Cardiac Extracellular Matrix Remodeling following Pressure Overload in Adiponectin Deficient Mice

scientific article published on 24 April 2015

The 22nd annual meeting of the European Tissue Repair Society (ETRS) in Athens, Greece

scientific article published on February 2013

The ED-A domain enhances the capacity of fibronectin to store latent TGF-β binding protein-1 in the fibroblast matrix.

scientific article published on 19 January 2018

The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers

scientific article

The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo

scientific article

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

scientific article published on 13 February 2014

The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication

scientific article published on 30 January 2018

The covalent attachment of adhesion molecules to silicone membranes for cell stretching applications

scientific article

The effect of lactose-conjugated silk biomaterials on the development of fibrogenic fibroblasts

scientific article published on 19 September 2008

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

scientific article published on 07 May 2015

The mechanical environment modulates intracellular calcium oscillation activities of myofibroblasts

scientific article

The mechanical memory of lung myofibroblasts

scientific article published on 13 March 2012

The myofibroblast at a glance

scientific article published on 10 July 2020

The myofibroblast in wound healing and fibrosis: answered and unanswered questions

scientific article

The myofibroblast matrix: implications for tissue repair and fibrosis.

scientific article published on January 2013

The myofibroblast: one function, multiple origins

scientific article

The myofibroblast: paradigm for a mechanically active cell

scientific article published on 03 October 2009

The role of the myofibroblast in tumor stroma remodeling

scientific article

The single-molecule mechanics of the latent TGF-β1 complex

scientific article

Tissue stiffness, latent TGF-beta1 activation, and mechanical signal transduction: implications for the pathogenesis and treatment of fibrosis

scientific article published in April 2009

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

scientific article published on 7 April 2004

Triplet Imaging of Oxygen Consumption During the Contraction of a Single Smooth Muscle Cell (A7r5)

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

scientific article published on January 2010

Tumor cell invasion is promoted by interstitial flow-induced matrix priming by stromal fibroblasts

scientific article published on 18 January 2011

Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation

scientific article

YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

scientific article

β-Catenin-regulated myeloid cell adhesion and migration determine wound healing

scientific article published on 16 May 2014