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List of works by Roberto Ria

90Y-ibritumomab tiuxetan as consolidation therapy after autologous stem cell transplantation in aggressive non-Hodgkin lymphoma

scientific article

A HGF/cMET autocrine loop is operative in multiple myeloma bone marrow endothelial cells and may represent a novel therapeutic target.

scientific article published on 11 September 2014

A VEGF-dependent autocrine loop mediates proliferation and capillarogenesis in bone marrow endothelial cells of patients with multiple myeloma.

scientific article published in December 2004

A multiple myeloma that progressed as type I cryoglobulinemia with skin ulcers and foot necrosis: A case report ⬇️

scientific article published on 01 September 2018

A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma

scientific article published in February 2003

A retrospective study of skeletal and disease-free survival benefits of zoledronic acid therapy in patients with multiple myeloma treated with novel agents ⬇️

scientific article published on November 18, 2012

Age and organ damage correlate with poor survival in myeloma patients: meta-analysis of 1435 individual patient data from 4 randomized trials

scientific article

Alpha(v)beta(3) integrin engagement enhances cell invasiveness in human multiple myeloma

scientific article published in August 2002

An experimental study in the chick embryo chorioallantoic membrane of the anti-angiogenic activity of cyclosporine in rheumatoid arthritis versus osteoarthritis

scientific article published on 01 August 2000

Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas

scientific article published on 01 January 2000

Angiogenesis and progression in human melanoma.

scientific article

Angiogenesis and tumor progression in melanoma

scientific article published in November 2000

Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomas

scientific article published on 01 March 2002

Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with upgrading and myometrial invasion in endometrial carcinoma

scientific article published on 01 September 1999

Angiogenesis in multiple myeloma

scientific article published on 17 October 2013

Anti-VEGF Drugs in the Treatment of Multiple Myeloma Patients

scientific article published on 06 June 2020

Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling

scientific article

Antiangiogenesis is produced by nontoxic doses of vinblastine

scientific article published on 01 December 1999

Aspirin, Warfarin, or Enoxaparin Thromboprophylaxis in Patients With Multiple Myeloma Treated With Thalidomide: A Phase III, Open-Label, Randomized Trial

scientific article published on 31 January 2011

Autologous transplant vs oral chemotherapy and lenalidomide in newly diagnosed young myeloma patients: a pooled analysis.

scientific article published on 23 December 2016

Bendamustine, Low-dose dexamethasone, and lenalidomide (BdL) for the treatment of patients with relapsed/refractory multiple myeloma confirms very promising results in a phase I/II study.

scientific article published on 21 July 2016

Biological activity of substrate-bound basic fibroblast growth factor (FGF2): recruitment of FGF receptor-1 in endothelial cell adhesion contacts

scientific article

Bone Marrow Stromal Cells-Induced Drug Resistance in Multiple Myeloma

scientific article published on 17 January 2020

Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma.

scientific article published on February 1999

Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.

scientific article

Bone marrow angiogenesis and progression in multiple myeloma

scientific article published on 08 June 2011

Bone marrow endothelial cells in multiple myeloma secrete CXC-chemokines that mediate interactions with plasma cells

scientific article

Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.

scientific article published on 2 September 2013

Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma

scientific article published on 01 May 1999

Bortezomib Treatment Modulates Autophagy in Multiple Myeloma

scientific article published on 18 February 2020

Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma

scientific article published on 13 November 2009

Bortezomib-dexamethasone as maintenance therapy or early retreatment at biochemical relapse versus observation in relapsed/refractory multiple myeloma patients: a randomized phase II study

scientific article published on 18 May 2020

Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial

scientific article published on 12 October 2010

Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: updated follow-up and improved survival

scientific article

Can a decreasing ultrafiltration profile affect the dialytic dose administered?

scientific article published on 01 October 2006

Cancer-related coagulopathy (Trousseau's syndrome): review of the literature and experience of a single center of internal medicine.

scientific article published on 02 March 2013

Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity.

scientific article

Chemotherapy plus lenalidomide versus autologous transplantation, followed by lenalidomide plus prednisone versus lenalidomide maintenance, in patients with multiple myeloma: a randomised, multicentre, phase 3 trial

scientific article

Circulating miRNA markers show promise as new prognosticators for multiple myeloma

scientific article

Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients

scientific article published on 12 January 2011

Continuous therapy in standard- and high-risk newly-diagnosed multiple myeloma: A pooled analysis of 2 phase III trials

scientific article published on 14 September 2018

Could multiple myeloma VEGF modify the systemic microcirculation?

scientific article published on 01 January 2012

Delayed complete remission in a patient with multiple myeloma

scientific article published in December 2008

Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8+ T-cell killing

scientific article

Development of vasculature targeting strategies for the treatment of chronic inflammatory diseases.

scientific article

Different Adaptive Responses to Hypoxia in Normal and Multiple Myeloma Endothelial Cells

scientific article published on 21 March 2018

Docetaxel versus paclitaxel for antiangiogenesis

scientific article published in February 2002

Does a reduction of adhesion molecules by LDL-apheresis have a role in the treatment of sudden hearing loss?

scientific article published in June 2006

Echocardiographic findings and plasma endothelin-1 levels in obese patients with and without obstructive sleep apnea

scientific article published on 18 September 2015

Effect of low-density lipoprotein apheresis on circulating endothelial progenitor cells in familial hypercholesterolemia

scientific article published on 20 May 2010

Efficacy and safety of once-weekly bortezomib in multiple myeloma patients.

scientific article published on 31 August 2010

Endothelial cells in the bone marrow of patients with multiple myeloma

scientific article

Endothelial differentiation of hematopoietic stem and progenitor cells from patients with multiple myeloma

scientific article published on 01 March 2008

Erythropoietin as an angiogenic factor in gastric carcinoma

scientific article published on 01 March 2003

Erythropoietin is involved in the angiogenic potential of bone marrow macrophages in multiple myeloma

scientific article

Evidence for bone marrow adult stem cell plasticity: properties, molecular mechanisms, negative aspects, and clinical applications of hematopoietic and mesenchymal stem cells transdifferentiation.

scientific article published on 27 March 2013

Extramedullary Plasmacytoma Mimicking Pancreatic Cancer: An Unusual Presentation.

scientific article published on 25 October 2016

Filgrastim, lenograstim and pegfilgrastim in the mobilization of peripheral blood progenitor cells in patients with lymphoproliferative malignancies

scientific article published on 11 April 2014

Four proteins governing overangiogenic endothelial cell phenotype in patients with multiple myeloma are plausible therapeutic targets

scientific article published on 03 October 2011

Functional and Biological Role of Endothelial Precursor Cells in Tumour Progression: A New Potential Therapeutic Target in Haematological Malignancies

scientific article

Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma

scientific article published on 04 April 2019

Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma.

scientific article

Gene expression profiling of normal thyroid tissue from patients with thyroid carcinoma

scientific article published on 18 April 2016

HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target

scientific article published on 2 December 2013

Halting pro-survival autophagy by TGFβ inhibition in bone marrow fibroblasts overcomes bortezomib resistance in multiple myeloma patients.

scientific article published on 21 October 2015

Heavy-Chain Diseases and Myeloma-Associated Fanconi Syndrome: an Update

scientific article published in January 2018

High-Risk Multiple Myeloma: Integrated Clinical and Omics Approach Dissects the Neoplastic Clone and the Tumor Microenvironment

scientific article published on 09 July 2019

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk Hodgkin’s lymphoma

scientific article published on 01 January 2012

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk non-Hodgkin lymphoma

scientific article published on 18 September 2011

Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma-Enhanced Angiogenesis: A Novel Therapeutic Target?

scientific article published on 05 December 2018

Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo

scientific article published on April 1999

Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis.

scientific article published on January 1998

Identify multiple myeloma stem cells: Utopia?

scientific article

In vivo time-course of the angiogenic response induced by multiple myeloma plasma cells in the chick embryo chorioallantoic membrane

scientific article published in September 2003

Increased matrix-metalloproteinase-2 and matrix-metalloproteinase-9 expression in the brain of dystrophic mdx mouse.

scientific article

Induction Therapy and Stem Cell Mobilization in Patients with Newly Diagnosed Multiple Myeloma ⬇️

scientific article published on May 31, 2012

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma.

scientific article

Is re-challenge still an option as salvage therapy in multiple myeloma? The case of REal-life BOrtezomib re-Use as secoND treatment for relapsed patients exposed frontline to bortezomib-based therapies (the REBOUND Study)

scientific article published on 23 October 2018

Is the efficacy of LDL apheresis in ischemic optic neuropathy linked to a reduction in endothelial activation markers?

scientific article

Jagged Ligands Enhance the Pro-Angiogenic Activity of Multiple Myeloma Cells

scientific article published on 11 September 2020

Lenalidomide and low-dose dexamethasone (Rd) versus bortezomib, melphalan, prednisone (VMP) in elderly newly diagnosed multiple myeloma patients: A comparison of two prospective trials.

scientific article published on 22 December 2016

Lenalidomide restrains motility and overangiogenic potential of bone marrow endothelial cells in patients with active multiple myeloma.

scientific article

Long-term effects of tibolone on circulating levels of vascular cell adhesion molecules and E-selectin in postmenopausal women

scientific article published on 11 September 2006

Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation

scientific article published on 01 May 2007

Maintenance in myeloma patients achieving complete response after upfront therapy: a pooled analysis

scientific article published on 19 April 2018

Managing myelodysplastic symptoms in elderly patients.

scientific article

Mast cell contribution to angiogenesis related to tumour progression.

scientific article

Mechanisms of Resistance to Anti-CD38 Daratumumab in Multiple Myeloma

scientific article published on 09 January 2020

Melphalan 200 mg/m(2) versus melphalan 100 mg/m(2) in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study

scientific article

Melphalan versus melphalan plus busulphan in conditioning to autologous stem cell transplantation for low-risk multiple myeloma

scientific article published in January 2004

Metronomic chemotherapy from rationale to clinical studies: a dream or reality?

scientific article published on 20 January 2015

Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma

scientific article published in May 2001

Modifications of the mouse bone marrow microenvironment favor angiogenesis and correlate with disease progression from asymptomatic to symptomatic multiple myeloma

scientific article published on 7 May 2015

Monoclonal gammopathy as a marker of primary cerebral lymphoma

scientific article published on 30 April 2009

Multiple myeloma macrophages: pivotal players in the tumor microenvironment.

scientific article

Neovascularisation, expression of fibroblast growth factor-2, and mast cells with tryptase activity increase simultaneously with pathological progression in human malignant melanoma

scientific article published in March 2003

Neutropenia and G-CSF in lymphoproliferative diseases

scientific article published on 19 November 2012

Novel agents and new therapeutic approaches for treatment of multiple myeloma.

scientific article

Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.

scientific article published on 26 June 2013

Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: updated results of a randomized controlled trial.

scientific article published on 27 May 2008

Osteolytic lesions, cytogenetic features and bone marrow levels of cytokines and chemokines in multiple myeloma patients: Role of chemokine (C-C motif) ligand 20.

scientific article

Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross-talk in the bone marrow of multiple myeloma patients

scientific article

Preparation and characterization of novel gellan gum hydrogels suitable for modified drug release.

scientific article published on 3 September 2009

Prognostic or predictive value of circulating cytokines and angiogenic factors for initial treatment of multiple myeloma in the GIMEMA MM0305 randomized controlled trial

scientific article published on 09 January 2019

Progression of mycosis fungoides is associated with changes in angiogenesis and expression of the matrix metalloproteinases 2 and 9

scientific article published on 01 September 1997

Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression

scientific article

Recurrent primary plasmacytoma of the eyelid with rapid regional metastasis

scientific article published on 01 March 2006

Right Heart Changes Impact on Clinical Phenotype of Amyloid Cardiac Involvement: A Single Centre Study

scientific article published on 18 October 2020

Role of basic fibroblast growth factor in the formation of the capillary plexus in the chick embryo chorioallantoic membrane. An in situ hybridization, immunohistochemical and ultrastructural study

scientific article published on 01 January 1998

Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients

scientific article published on 22 February 2016

Role of hematopoietic growth factors in angiogenesis.

scientific article

Safety and efficacy of bortezomib-melphalan-prednisone-thalidomide followed by bortezomib-thalidomide maintenance (VMPT-VT) versus bortezomib-melphalan-prednisone (VMP) in untreated multiple myeloma patients with renal impairment

scientific article published on 27 September 2011

Salvage therapy with thalidomide in patients with advanced relapsed/refractory multiple myeloma

scientific article

Salvage treatment with lenalidomide and dexamethasone in relapsed/refractory mantle cell lymphoma: clinical results and effects on microenvironment and neo-angiogenic biomarkers

scientific article

Serum levels of angiogenic cytokines decrease after antineoplastic radiotherapy

scientific article published on 01 December 2004

Serum levels of angiogenic cytokines decrease after radiotherapy in non-Hodgkin lymphomas

scientific article published on 13 September 2008

Soluble intercellular adhesion molecule 1 and soluble vascular cell adhesion molecule 1 in sudden hearing loss

scientific article published in June 2008

Subcutaneous immunoglobulins in patients with multiple myeloma and secondary hypogammaglobulinemia.

scientific article published on 27 November 2017

Suspected Pericardial Tuberculosis Revealed as an Amyloid Pericardial Mass

scientific article published on 17 October 2018

Systemic sclerosis stimulates angiogenesis in the chick embryo chorioallantoic membrane

scientific article published in January 1998

TNP-470 and recombinant human interferon-alpha2a inhibit angiogenesis synergistically

scientific article published on 01 June 2000

Treatment Intensification With Autologous Stem Cell Transplantation and Lenalidomide Maintenance Improves Survival Outcomes of Patients With Newly Diagnosed Multiple Myeloma in Complete Response

scientific article published on 28 May 2018

Vascular endothelial growth factor and its receptors in multiple myeloma.

scientific article

Vasculogenic mimicry by bone marrow macrophages in patients with multiple myeloma.

scientific article

alpha(v)beta(3) integrin engagement modulates cell adhesion, proliferation, and protease secretion in human lymphoid tumor cells.

scientific article published in August 2001

“Real world” outcome of lenalidomide plus dexamethasone in the setting of recurrent and refractory multiple myeloma: Extended follow-up of a retrospective multicenter study by the “rete ematologica pugliese”

scientific article published on 23 December 2014

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