List of works - Rosanna Filosa

2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone derivatives as new anti Flaviviridae inhibitors

scientific article published on 17 March 2011

3-Carboxylate-Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions

Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions

article published in 2012

Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis

scientific article published on 28 March 2008

Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of α-amino acids 3-substituted phthalides or isoindolinones

scholarly article in RSC Advances, vol. 4 no. 9, 2014

Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.

scientific article published on 30 April 2013

Design of inhibitors of influenza virus membrane fusion: synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series

scientific article published on 22 May 2013

Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands

scientific article published on 14 November 2008

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands

scientific article published on September 2011

Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase ⬇️

scientific article published on June 27, 2013

Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.

scientific article published on May 2014

Evaluation of alternative strategies to optimize ketorolac transdermal delivery.

scientific article published on 04 August 2006

Exploring the role of chloro and methyl substitutions in 2-phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition

scientific article published on 07 December 2015

Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase

scientific article published on 14 May 2014

In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat).

scientific article

Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate

scientific article published on 28 November 2006

Multi-component, regio-selective aldol addition of β-ketoesters to aldehydes: scope and applications

article

N, N' (4,5-dihydro-1h-imidazol-2-yl)3-aza-1,10-decane-diamine and N, N'(4,5-dihydro-1H-imidazol-2-yl)3-aza-1, 10-dodecane-diamine antagonize cell proliferation as selective ligands towards topoisomerase II.

scientific article published on October 2006

Natural compounds in anti-leukaemic therapy: a review.

scientific article published on June 2011

New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on β-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone

Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes

scientific article published on 24 February 2015

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin

scientific article published on 24 April 2013

Protective effects of raspberry on the oxidative damage in HepG2 cells through Keap1/Nrf2-dependent signaling pathway

scientific article published on 26 August 2019

Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma

scientific article published on 10 October 2017

Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation

scientific article

Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication

scientific article

Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues ⬇️

scientific article published on November 24, 2010

Synthesis and Preliminary Biological Evaluation of 2′-Substituted 2-(3′-Carboxybicyclo[1.1.1]pentyl)glycine Derivatives as Group I Selective Metabotropic Glutamate Receptor Ligands

scientific article published on 01 March 2006

Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures

Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine.

scientific article published on 5 December 2006

Synthesis and cytotoxic activity of new β-carboline derivatives.

scientific article published on June 2011

Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of β-Keto Esters and Malonates to Aldehydes

article

List of works by Rosanna Filosa

2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone derivatives as new anti Flaviviridae inhibitors

3-Carboxylate-Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions

Active methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactions

Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis

Cascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of α-amino acids 3-substituted phthalides or isoindolinones

Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.

Design of inhibitors of influenza virus membrane fusion: synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series

Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands

Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase ⬇️

Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.

Evaluation of alternative strategies to optimize ketorolac transdermal delivery.

Exploring the role of chloro and methyl substitutions in 2-phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibition

Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase

In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat).

Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate

Multi-component, regio-selective aldol addition of β-ketoesters to aldehydes: scope and applications

N, N' (4,5-dihydro-1h-imidazol-2-yl)3-aza-1,10-decane-diamine and N, N'(4,5-dihydro-1H-imidazol-2-yl)3-aza-1, 10-dodecane-diamine antagonize cell proliferation as selective ligands towards topoisomerase II.

Natural compounds in anti-leukaemic therapy: a review.

New chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on β-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinone

Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin

Protective effects of raspberry on the oxidative damage in HepG2 cells through Keap1/Nrf2-dependent signaling pathway

Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma

Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation

Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication

Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues ⬇️

Synthesis and Preliminary Biological Evaluation of 2′-Substituted 2-(3′-Carboxybicyclo[1.1.1]pentyl)glycine Derivatives as Group I Selective Metabotropic Glutamate Receptor Ligands

Synthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related Structures

Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine.

Synthesis and cytotoxic activity of new β-carboline derivatives.

Trimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of β-Keto Esters and Malonates to Aldehydes