List of works - Joaquín M Campos

1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles

scientific article published on 01 February 2007

1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

scientific article published on 01 December 2005

A New Systematization of the Conformational Behavior of Seven-Membered Rings. Isoclinal Anomeric and Related Orientations(1)

scientific article published on 01 January 1997

A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.

scientific article published on 24 November 2006

Alkylated Sesamol Derivatives as Potent Antioxidants

scientific article published on 21 July 2020

An Antioxidant Potential, Quantum-Chemical and Molecular Docking Study of the Major Chemical Constituents Present in the Leaves of Curatella americana Linn

scientific article published on 20 July 2018

An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods

scientific article published on 29 October 2018

Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell lines.

scientific article published on 10 February 2014

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine.

scientific article published on 27 May 2011

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

scientific article published on January 2008

Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells

scientific article published on December 2007

Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation.

scientific article published on February 2005

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors

scientific article published in August 2003

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

scientific article published on 29 October 2013

Choline kinase inhibitors as a novel approach for antiproliferative drug design

scientific article

Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides

scientific article published on January 2003

Conformational dynamics of a bispyridinium cyclophane

scientific article published in October 2003

Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors.

scientific article published in January 2007

Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.

scientific article

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers

scientific article published on 01 October 2008

From a classic approach in cancer chemotherapy towards differentiation therapy: acyclic and cyclic seven-membered 5-fluorouracil O,N-acetals.

scientific article

GR-891: a novel 5-fluorouracil acyclonucleoside prodrug for differentiation therapy in rhabdomyosarcoma cells

scientific article published on February 1999

Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives

scientific article published on November 2004

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.

scientific article

Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos

scientific article published on 18 April 2019

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity

scientific article

Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

scientific article published on 14 August 2019

Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches

scientific article published on 10 March 2020

Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

scientific article published on 12 September 2020

Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening

scientific article published on 25 January 2019

Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach

scientific article published in 2022

Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models

scientific article published in March 2002

In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity

scientific article published on 15 April 2019

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations

scientific article published on 12 March 2019

Influence of the linker in bispyridium compounds on the inhibition of human choline kinase

scientific article

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

scientific article published on December 2003

Inhibition of immune complex-mediated neutrophil oxidative metabolism: a pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures

scientific article published on 15 July 2007

Insight into the inhibition of human choline kinase: homology modeling and molecular dynamics simulations

scientific article published on 01 November 2006

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

scientific article

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

scientific article published on 3 December 2010

Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells.

scientific article

QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design

scientific article

QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?

scientific article

Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds

scientific article

Selection and preliminary characterization of a Pseudomonas aeruginosa strain mineralizing selected isomers in a branchedchain dodecylbenzenesulphonate mixture.

scientific article

Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom

scientific article published in February 2006

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

scientific article

Synthesis and NMR studies on a C3-symmetrical triquinolina triscationic bicyclophane

scientific article published on 01 July 2005

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

scientific article published on 26 May 2011

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

scientific article

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives

scientific article published on April 2004

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

scientific article

Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

article

Towards a model for the inhibition of choline kinase by a new type of inhibitor.

scientific article

Two tautomeric polymorphs of 2,6-dichloropurine

scientific article published on 05 November 2011

List of works by Joaquín M Campos

1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles

1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

A New Systematization of the Conformational Behavior of Seven-Membered Rings. Isoclinal Anomeric and Related Orientations(1)

A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.

Alkylated Sesamol Derivatives as Potent Antioxidants

An Antioxidant Potential, Quantum-Chemical and Molecular Docking Study of the Major Chemical Constituents Present in the Leaves of Curatella americana Linn

An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods

Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell lines.

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine.

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells

Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation.

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

Choline kinase inhibitors as a novel approach for antiproliferative drug design

Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides

Conformational dynamics of a bispyridinium cyclophane

Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors.

Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers

From a classic approach in cancer chemotherapy towards differentiation therapy: acyclic and cyclic seven-membered 5-fluorouracil O,N-acetals.

GR-891: a novel 5-fluorouracil acyclonucleoside prodrug for differentiation therapy in rhabdomyosarcoma cells

Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.

Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity

Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches

Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening

Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach

Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models

In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations

Influence of the linker in bispyridium compounds on the inhibition of human choline kinase

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

Inhibition of immune complex-mediated neutrophil oxidative metabolism: a pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures

Insight into the inhibition of human choline kinase: homology modeling and molecular dynamics simulations

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells.

QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design

QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?

Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds

Selection and preliminary characterization of a Pseudomonas aeruginosa strain mineralizing selected isomers in a branchedchain dodecylbenzenesulphonate mixture.

Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

Synthesis and NMR studies on a C3-symmetrical triquinolina triscationic bicyclophane

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

Towards a model for the inhibition of choline kinase by a new type of inhibitor.

Two tautomeric polymorphs of 2,6-dichloropurine