List of works - Giovanni Natile

"Lantern-Shaped" Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2).

scientific article

A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data

A NMR, X-ray, and DFT combined study on the regio-chemistry of nucleophilic addition to platinum(II) coordinated terminal olefins

article

A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO).

scientific article published on July 2013

A new polymorph of dichlorido(1,10-phenanthroline)platinum(II)

Activation of ketones by electrophilic metal complexes: Synthesis of some ketonyl platinum(II) complexes and X-ray crystal structure of [PtCl{CH2C(O)CH3}(1,10-phenanthroline)]·1/2Y (Y=H2O or CH2Cl2)

Aggregation pathways of native-like ubiquitin promoted by single-point mutation, metal ion concentration and dielectric constant of the medium.

scientific article published on 20 December 2017

Aiding Factors in the Formation of Azaplatinacyclobutane Rings – X-ray and Crystal Structure of [Pt{CH(Ph)CH2NEt2-κC,κN}(N,N,N′,N′-tetramethylethylenediamine)]+ and of Its Open-Chain Precursor

Amyloid transition of ubiquitin on silver nanoparticles produced by pulsed laser ablation in liquid as a function of stabilizer and single-point mutations.

scientific article

Antitumortrans Platinum Complexes can Form Cross-Links with Adjacent Purine Groups

Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir

scientific article published on August 2004

Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands

scientific article published in June 2010

Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds

article

C60@Lysozyme: direct observation by nuclear magnetic resonance of a 1:1 fullerene protein adduct

scientific article

Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)]

article

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

scientific article published on 27 May 2015

Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).

scientific article published on 14 August 2013

Cisplatin handover between copper transporters: the effect of reducing agents

scientific article published on 01 May 2014

Computational metallomics of the anticancer drug cisplatin

scientific article

Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.

scientific article published on 17 August 2007

Conformational selection of ubiquitin quaternary structures driven by zinc ions

scientific article published on 10 October 2013

Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin

scientific article

Copper-triggered aggregation of ubiquitin

scientific article

Crystallographic analysis of metal-ion binding to human ubiquitin

scientific article

Cytotoxicity of some platinum(IV) complexes with ethylenediamine-N,N'-di-3-propionato ligand

scientific article published on August 2004

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.

scientific article published on February 2010

Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.

scientific article published on 25 December 2007

Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands.

scientific article published on 18 December 2015

Cytotoxictrans-Oriented Platinum Complexes only Form Adducts with Single-Stranded Oligodeoxynucleotides

scientific article published on 01 July 2004

DNA fragment conformations in adducts with Kiteplatin

article

DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes ⬇️

scientific article published on November 15, 2003

Dalton communication. Intramolecular nucleophilic addition of the oxygen of a nitro ligand onto the cis olefin in cationic complexes of platinum(II)

article

Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent

article

Differential Reactivity of Metal Binding Domains of Copper ATPases towards Cisplatin and Colocalization of Copper and Platinum

scientific article published on 30 May 2018

Differential genotoxic effects of antitumor trans-[PtCl(2)(E-iminoether)(2)] and cisplatin in Escherichia coli.

scientific article

Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs

scientific article

Direct addition of alcohols to organonitriles activated by ligation to a platinum(IV) center.

scientific article

Effect of Thioethers on DNA Platination bytrans-Platinum Complexes

scientific article published on 03 August 2011

Effect of chirality in platinum drugs

Effect of in vivo post-translational modifications of the HMGB1 protein upon binding to platinated DNA: a molecular simulation study

scientific article

Encapsulation of lipophilic kiteplatin Pt(iv) prodrugs in PLGA-PEG micelles.

scientific article

Endocyclic versus exocyclic N-coordination to platinum(II) of some nitro-9-[(2-dialkylaminoethyl)amino]acridines

Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+.

scientific article

Factors influencing conformer equilibria in retro models of cisplatin-DNA adducts as revealed by moderately dynamic (N,N'-dimethyl-2,3-diaminobutane)PtG(2) retro models (G = a guanine derivative).

scientific article published in September 2002

Formation of adenine-N3/guanine-N7 cross-link in the reaction of trans-oriented platinum substrates with dinucleotides

scientific article published in October 2002

Ground-state stability and rotational activation parameters for individual rotamers of (R,S,S,R)-(N,N'-dimethyl-2,3-diaminobutane)PtG(2) complexes (G = 9-EtG, 3'-GMP, and 5'-GMP).

scientific article published in February 2003

H/D exchange at sp(3) carbons in the coordination sphere of platinum(II).

scientific article published in March 2014

High barrier to rotation about the Pd–N bond in trans-dichloro-dihydrazonepalladium(II) complexes

article published in 1977

High resolution proton MR spectroscopy of cerebrospinal fluid in MS patients. Comparison with biochemical changes in demyelinating plaques

scientific article published in December 1996

Hydrophobic Nanocrystals Coated with an Amphiphilic Polymer Shell: A General Route to Water Soluble Nanocrystals

Imprinting Structural Information from a GpG Ligand into the Configuration of a Chiral Diamine Ligand through Second-Sphere Communication in Platinum(II) Complexes

scientific article published on 01 January 2001

In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum-iminoether complexes with different configuration at the iminoether ligands

scientific article

Influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand

scientific article published on 01 February 2000

Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)]

article published in 2004

Insertion of alkynes into Pt-X bonds of square planar [PtX2(N^N)] (X = Cl, Br, I) complexes

scientific article published in June 2014

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

scientific article published on 9 October 2007

Interaction between platinum complexes and a methionine motif found in copper transport proteins

scientific article published in January 2007

Isomerization of platinum-coordinated iminoethers induced by spectator ligands: stabilization of the Z anti configuration.

scientific article

Markovnikov versus anti-Markovnikov selectivity in the amination of terminal olefins coordinated to platinum(II)

article published in 2006

Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs

scientific article published on 19 July 2019

Mechanistic insight into the inhibition of matrix metalloproteinases by platinum substrates.

scientific article

Methionine can favor DNA platination by trans-coordinated platinum antitumor drugs

scientific article published in January 2009

Modification of second-sphere communication, leading to an unusually high abundance of the head-to-head conformer of cisplatin cross-link retro models

scientific article published in February 2002

Modulation of properties in analogues of Zeise's anion on changing the ligand trans to ethene. X-ray crystal structures of trans-[PtCl2(OH)(η2-C2H4)]- and trans-[PtCl2(η1-CH2NO2)(η2-C2H4)]-.

scientific article published on 20 January 2012

Molecular Recognition of Platinated DNA from Chromosomal HMGB1.

scientific article published on 10 July 2014

Molecular aspects of antitumor effects of a new platinum(IV) drug.

scientific article published on 8 August 2006

Monofunctional platinum(II) complexes with potent tumor cell growth inhibitory activity: the effect of a hydrogen-bond donor/acceptor N-heterocyclic ligand.

scientific article published on 2 May 2014

Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions

scientific article published on 14 July 2018

NMR Studies of Models Having the Pt(d(GpG)) 17-Membered Macrocyclic Ring Formed in DNA by Platinum Anticancer Drugs: Pt Complexes with Bulky Chiral Diamine Ligands

scientific article published on 21 April 2011

NMR and X-ray characterization of a platinum(II) complex with (−)sparteine

NMR and X-ray structural characterization of a cisplatin analogue able to slow down the Pt-N7 rotation of a coordinated guanine base by a billion-fold times: 2,2'-bipiperidine(dimethylmalonato)platinum(II) complex

scientific article published on 30 April 2008

NMR investigation of the spontaneous thermal- and/or photoinduced reduction of trans dihydroxido Pt(IV) derivatives.

scientific article

Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates

scientific article published on 10 November 2011

New chemistry of olefin complexes of platinum(II) unravelled by basic conditions: synthesis and properties of elusive cationic species

scientific article published on 21 August 2008

Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1-Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses

article

Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy

scientific article

Origins of the distortions in the base pair step adjacent to platinum anticancer drug-DNA adducts. Fundamental NMR solution studies utilizing right-handed cross-link models having 5'- and 3'-flanking residues.

scientific article published in September 2009

Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione

scientific article published on 06 September 2019

Photo-isomerisation of alkenyl complexes of platinum(II): structural, spectroscopic, kinetic and computational investigations.

scientific article

Platination of the copper transporter ATP7A involved in anticancer drug resistance

scientific article published in August 2014

Platinum complexes with imino ethers or cyclic ligands mimicking imino ethers: synthesis, in vitro antitumour activity, and DNA interaction properties

scientific article published on 6 July 2004

Platinum(II) Complexes with the Diethyl Aminomethylphosphonate Ligand (amp): Characterization, Properties, and Unusual Solution Behavior

Platinum(II) complexes containing iminoethers: a trans platinum antitumour agent

scientific article published on 01 December 1995

Platinum(II) complexes with antitumoral/antiviral aromatic heterocycles: effect of glutathione upon in vitro cell growth inhibition

scientific article

Platinum(II) complexes with bioactive carrier ligands having high affinity for the translocator protein.

scientific article published on July 2010

Platinum(IV) Complexes of trans-1,2-diamino-4-cyclohexene: Prodrugs Affording an Oxaliplatin Analogue that Overcomes Cancer Resistance

scientific article published on 27 March 2020

Platinum-based antitumor drugs containing enantiomerically pure alpha-trifluoromethyl alanine as ligand.

scientific article

Platinum-bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis

scientific article published on 30 December 2010

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

scientific article published on 24 October 2011

Reaction of Zn7Metallothionein withcis- andtrans-[Pt(N-donor)2Cl2] Anticancer Complexes: trans-PtIIComplexes Retain Their N-Donor Ligands

scientific article published on 01 August 2007

Reactivity of kiteplatin with S-donor biomolecules and nucleotides

scientific article published on 01 September 2014

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

scientific article

Rotamer stability in cis-[Pt(diA)G2] complexes (diA = diamine derivative and G = guanine derivative) mediated by carrier-ligand amine stereochemistry as revealed by circular dichroism spectroscopy

scientific article published in September 2005

Solution behavior of amidine complexes: an unexpected cis/trans isomerization and formation of di- and trinuclear platinum(III) and platinum(II) species

scientific article

Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.

scientific article published on 19 July 2013

Steric constraints and addition reactions in platinum(II) complexes containing 2,9-dimethyl-1,10-phenanthroline (Me2-phen). X-ray crystal structures of [PtBr2(Me2-phen)] and [PtI2(Me2-phen)]

article

Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance

scientific article published on 3 August 2006

Structural Determinants of Cisplatin and Transplatin Binding to the Met-Rich Motif of Ctr1: A Computational Spectroscopy Approach

scientific article

Structural biology of cisplatin complexes with cellular targets: the adduct with human copper chaperone atox1 in aqueous solution.

scientific article published on 8 August 2014

Structural probing of Zn(II), Cd(II) and Hg(II) binding to human ubiquitin

scientific article

Synthesis and characterization of a platinum(II) complex tethered to a ligand of the peripheral benzodiazepine receptor

scientific article published on 8 February 2007

Synthesis and crystal structure of the first trinuclear chloride-bridged platinum(II) complex with mutually perpendicular co-ordination planes: cyclo-tri-µ,-chloro-tris[chloro(1-hydroxy-1-imino-2,2-dimethylpropane)platinum(II)]-dichloromethane (0.5/

Synthesis and in vitro antitumor activity of platinum acetonimine complexes.

scientific article published on January 2006

Synthesis and spectroscopic and structural characterization of different configurations of the tridentate amine ligand N,N′,N′′-trimethyldiethylenetriamine coordinated to platinum

Synthesis and structural characterization of isomeric ‘lantern-shaped’ platinum(III) complexes of formula [Pt2(PPh3)X{N(H)C(R)O}4](NO3)2 (X=PPh3, H2O)

article

Synthesis, Characterization, and in Vitro Evaluation of a New TSPO-Selective Bifunctional Chelate Ligand

scientific article published on 30 March 2014

Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands.

scientific article

Synthesis, characterization, and biological activity of platinum II, III, and IV pivaloamidine complexes

scientific article

Synthesis, characterization, and cytotoxicity of dinuclear platinum-bisphosphonate complexes to be used as prodrugs in the local treatment of bone tumours

scientific article

Synthesis, characterization, and in vitro evaluation of new coordination complexes of platinum(II) and rhenium(I) with a ligand targeting the translocator protein (TSPO).

scientific article

The First Example of a Dinuclear Platinum(III) Complex with Three Bridging Ligands

The First Pure ΛHT Rotamer of a Complex with acis-[Metal(nucleotide)2] Unit: Acis-[Pt(amine)2(nucleotide)2] ΛHT Rotamer with Unique Molecular Structural Features

scientific article published on 01 January 2007

The thermodynamics of translesion DNA synthesis past major adducts of enantiomeric analogues of antitumor cisplatin.

scientific article published on 28 February 2012

The unexpected reactivity of Zeise's anion in strong basic medium discloses new substitution patterns at the platinum centre

scientific article published on 25 January 2006

Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug.

scientific article

Trans-platinum complexes in cancer therapy

scientific article published on January 2007

Translocation of platinum anticancer drugs by human copper ATPases ATP7A and ATP7B.

scientific article published on 27 December 2013

Two polymorphs of potassium trichloro[diethyl (methylsulfinylmethyl)phosphonate-κS]platinum(II) withZ′ = 1 and 3 in the space groupP212121

scientific article published on 30 June 2006

Ubiquitin Stability and the Lys 63-Linked Polyubiquitination Site Are Compromised on Copper Binding

scientific article published on 01 January 2007

Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.

scientific article published in January 2008

Unusual interstrand Pt(S,S-diaminocyclohexane)-GG crosslink formed by rearrangement of a classical intrastrand crosslink within a DNA duplex

scientific article published in February 2010

Unusual reactivity at a platinum center determined by the ligands and the solvent environment.

scientific article

X-ray structural characterization of the bis-guanine derivative of a cisplatin analogue having just one proton on each coordinated nitrogen and a head-to-head conformation: [Pt{(+/-)-N,N'-dimethyl-2,3-diaminobutane}(9-ethyl-guanine)2]dinitrate.

scientific article published on September 2010

X-ray structure and circular dichroism of pure rotamers of bis[guanosine-5'-monophosphate(-1)](N,N,N',N'-tetramethylcyclohexyl-1,2-diamine)platinum(II) complexes that have R,R and S,S configurations at the asymmetric diamine

scientific article published in December 2003

X-ray structures of the first platinum complexes with Z configuration iminoether ligands: trans-dichlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(II) and trans-tetrachlorobis(1-imino-1-methoxy-2,2'-dimethylpropane)platinum(IV).

scientific article published in February 2002

trans-Chloridobis[(Z)-1-imino-1-methoxyethane-κN](triphenylphosphane-κP)platinum(II) chloride monohydrate

scientific article published on 18 October 2012

List of works by Giovanni Natile

"Lantern-Shaped" Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2).

A Molecular Tool for Measuring the Electron-Acceptor Ability of Ligands from Crystallographic Data

A NMR, X-ray, and DFT combined study on the regio-chemistry of nucleophilic addition to platinum(II) coordinated terminal olefins

A model radiopharmaceutical agent targeted to translocator protein 18 kDa (TSPO).

A new polymorph of dichlorido(1,10-phenanthroline)platinum(II)

Activation of ketones by electrophilic metal complexes: Synthesis of some ketonyl platinum(II) complexes and X-ray crystal structure of [PtCl{CH2C(O)CH3}(1,10-phenanthroline)]·1/2Y (Y=H2O or CH2Cl2)

Aggregation pathways of native-like ubiquitin promoted by single-point mutation, metal ion concentration and dielectric constant of the medium.

Aiding Factors in the Formation of Azaplatinacyclobutane Rings – X-ray and Crystal Structure of [Pt{CH(Ph)CH2NEt2-κC,κN}(N,N,N′,N′-tetramethylethylenediamine)]+ and of Its Open-Chain Precursor

Amyloid transition of ubiquitin on silver nanoparticles produced by pulsed laser ablation in liquid as a function of stabilizer and single-point mutations.

Antitumortrans Platinum Complexes can Form Cross-Links with Adjacent Purine Groups

Antiviral properties and cytotoxic activity of platinum(II) complexes with 1,10-phenanthrolines and acyclovir or penciclovir

Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands

Bisphosphonate complexation and calcium doping in silica xerogels as a combined strategy for local and controlled release of active platinum antitumor compounds

C60@Lysozyme: direct observation by nuclear magnetic resonance of a 1:1 fullerene protein adduct

Cationic intermediates in oxidative addition reactions of Cl2 to [PtCl2(cis-1,4-DACH)]

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).

Cisplatin handover between copper transporters: the effect of reducing agents

Computational metallomics of the anticancer drug cisplatin

Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.

Conformational selection of ubiquitin quaternary structures driven by zinc ions

Conformer distribution in (cis-1,4-DACH)bis(guanosine-5'-phosphate)platinum(II) adducts: a reliable model for DNA adducts of antitumoral cisplatin

Copper-triggered aggregation of ubiquitin

Crystallographic analysis of metal-ion binding to human ubiquitin

Cytotoxicity of some platinum(IV) complexes with ethylenediamine-N,N'-di-3-propionato ligand

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.

Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.

Cytotoxicity-boosting of kiteplatin by Pt(IV) prodrugs with axial benzoate ligands.

Cytotoxictrans-Oriented Platinum Complexes only Form Adducts with Single-Stranded Oligodeoxynucleotides

DNA fragment conformations in adducts with Kiteplatin

DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes ⬇️

Dalton communication. Intramolecular nucleophilic addition of the oxygen of a nitro ligand onto the cis olefin in cationic complexes of platinum(II)

Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent

Differential Reactivity of Metal Binding Domains of Copper ATPases towards Cisplatin and Colocalization of Copper and Platinum

Differential genotoxic effects of antitumor trans-[PtCl(2)(E-iminoether)(2)] and cisplatin in Escherichia coli.

Dinuclear Pt(II)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs

Direct addition of alcohols to organonitriles activated by ligation to a platinum(IV) center.

Effect of Thioethers on DNA Platination bytrans-Platinum Complexes

Effect of chirality in platinum drugs

Effect of in vivo post-translational modifications of the HMGB1 protein upon binding to platinated DNA: a molecular simulation study

Encapsulation of lipophilic kiteplatin Pt(iv) prodrugs in PLGA-PEG micelles.

Endocyclic versus exocyclic N-coordination to platinum(II) of some nitro-9-[(2-dialkylaminoethyl)amino]acridines

Energetics, conformation, and recognition of DNA duplexes modified by methylated analogues of [PtCl(dien)]+.

Factors influencing conformer equilibria in retro models of cisplatin-DNA adducts as revealed by moderately dynamic (N,N'-dimethyl-2,3-diaminobutane)PtG(2) retro models (G = a guanine derivative).

Formation of adenine-N3/guanine-N7 cross-link in the reaction of trans-oriented platinum substrates with dinucleotides

Ground-state stability and rotational activation parameters for individual rotamers of (R,S,S,R)-(N,N'-dimethyl-2,3-diaminobutane)PtG(2) complexes (G = 9-EtG, 3'-GMP, and 5'-GMP).

H/D exchange at sp(3) carbons in the coordination sphere of platinum(II).

High barrier to rotation about the Pd–N bond in trans-dichloro-dihydrazonepalladium(II) complexes

High resolution proton MR spectroscopy of cerebrospinal fluid in MS patients. Comparison with biochemical changes in demyelinating plaques

Hydrophobic Nanocrystals Coated with an Amphiphilic Polymer Shell: A General Route to Water Soluble Nanocrystals

Imprinting Structural Information from a GpG Ligand into the Configuration of a Chiral Diamine Ligand through Second-Sphere Communication in Platinum(II) Complexes

In vitro and in vivo antitumour activity and cellular pharmacological properties of new platinum-iminoether complexes with different configuration at the iminoether ligands

Influence of Carrier Ligand NH Hydrogen Bonding to the O6 and Phosphate Group of Guanine Nucleotides in Platinum Complexes with a Single Guanine Ligand

Influence of steric and electronic factors in the stabilization of five-coordinate ethylene complexes of platinum(II): X-ray crystal structure of [PtCl2(2,9-dimethyl-1,10-phenanthroline-5,6-dione)]

Insertion of alkynes into Pt-X bonds of square planar [PtX2(N^N)] (X = Cl, Br, I) complexes

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

Interaction between platinum complexes and a methionine motif found in copper transport proteins

Isomerization of platinum-coordinated iminoethers induced by spectator ligands: stabilization of the Z anti configuration.

Markovnikov versus anti-Markovnikov selectivity in the amination of terminal olefins coordinated to platinum(II)

Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs

Mechanistic insight into the inhibition of matrix metalloproteinases by platinum substrates.

Methionine can favor DNA platination by trans-coordinated platinum antitumor drugs

Modification of second-sphere communication, leading to an unusually high abundance of the head-to-head conformer of cisplatin cross-link retro models

Modulation of properties in analogues of Zeise's anion on changing the ligand trans to ethene. X-ray crystal structures of trans-[PtCl2(OH)(η2-C2H4)]- and trans-[PtCl2(η1-CH2NO2)(η2-C2H4)]-.

Molecular Recognition of Platinated DNA from Chromosomal HMGB1.

Molecular aspects of antitumor effects of a new platinum(IV) drug.

Monofunctional platinum(II) complexes with potent tumor cell growth inhibitory activity: the effect of a hydrogen-bond donor/acceptor N-heterocyclic ligand.

Multi-Acting Mitochondria-Targeted Platinum(IV) Prodrugs of Kiteplatin with α-Lipoic Acid in the Axial Positions

NMR Studies of Models Having the Pt(d(GpG)) 17-Membered Macrocyclic Ring Formed in DNA by Platinum Anticancer Drugs: Pt Complexes with Bulky Chiral Diamine Ligands

NMR and X-ray characterization of a platinum(II) complex with (−)sparteine

NMR and X-ray structural characterization of a cisplatin analogue able to slow down the Pt-N7 rotation of a coordinated guanine base by a billion-fold times: 2,2'-bipiperidine(dimethylmalonato)platinum(II) complex

NMR investigation of the spontaneous thermal- and/or photoinduced reduction of trans dihydroxido Pt(IV) derivatives.

Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates

New chemistry of olefin complexes of platinum(II) unravelled by basic conditions: synthesis and properties of elusive cationic species

Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1-Methyl-7-Azaindole: Synthesis, Characterization, and Cellular Responses

Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy

Origins of the distortions in the base pair step adjacent to platinum anticancer drug-DNA adducts. Fundamental NMR solution studies utilizing right-handed cross-link models having 5'- and 3'-flanking residues.

Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione

Photo-isomerisation of alkenyl complexes of platinum(II): structural, spectroscopic, kinetic and computational investigations.