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List of works by Angela L. Tyner

A New Method for Determining the Status of p53 in Tumor Cell Lines of Different Origin ⬇️

scientific article published on January 1, 2003

A conserved phosphorylation site within the forkhead domain of FoxM1B is required for its activation by cyclin-CDK1.

scientific article published on 08 September 2009

A family of proteins accumulating in ectoderm of sea urchin embryos specified by two related cDNA clones ⬇️

scientific article published on 01 June 1982

A novel p21WAF1/CIP1 transcript is highly dependent on p53 for its basal expression in mouse tissues

scientific article published on October 2004

Accumulation in embryogenesis of five mRNAs enriched in the ectoderm of the sea urchin pluteus ⬇️

scientific article published on October 30, 1981

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

scientific article (publication date: 3 July 2003)

An N-terminal inhibitory domain modulates activity of FoxM1 during cell cycle

scientific article

Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase

scientific article

Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases ⬇️

scientific article published on January 1, 2003

Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4

scientific journal article

Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK

scientific article

Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis

scientific article published on 26 October 2015

Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro

scientific article

Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line

scientific article published on 5 February 2003

Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle

scientific article published on May 2004

Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer

scientific article published on 10 February 2013

Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells

scientific article

Deregulation of FoxM1b leads to tumour metastasis

scientific article

Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium.

scientific article published in November 2004

Differential regulation of D-type cyclins in the mouse intestine

scientific article published on 16 January 2006

Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane

scientific article published on 8 July 2011

FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors

scientific article published on 20 April 2011

FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression

scientific article published on 5 November 2007

FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness

scientific article

FoxM1, a critical regulator of oxidative stress during oncogenesis

scientific article

Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine

scientific article

Histochemical examination of periodontal junctional epithelium in p21/p27 double knockout mice

scientific article published in June 2004

Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6

scientific article

Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin

scientific article published on 10 August 2006

Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis

scientific article published on 06 June 2009

Inhibition of colon cancer cell proliferation by the dietary compound conjugated linoleic acid is mediated by the CDK inhibitor p21CIP1/WAF1.

scientific article

Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer

scientific article published on 16 March 2016

Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin

scientific article

P21 functions to maintain quiescence of p27-deficient hepatocytes

scientific article published on 28 August 2002

PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.

scientific article published on 15 November 2017

PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer

scientific article published on 15 July 2013

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

scientific article

Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin

scientific article

Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor

scientific journal article

Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine

scientific journal article

Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.

scientific article

Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT ⬇️

scientific article published on September 5, 2013

Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.

scientific article published on 09 December 2013

Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate

scientific journal article

RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK.

scientific article

Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats

scientific article

Targeting FoxM1 effectively retards p53-null lymphoma and sarcoma

scientific article

Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage

scientific article published on 18 September 2012

The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury

scientific journal article

The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin

scientific article

The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis

scientific article

The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.

scientific article

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

scientific article

The zonal expression of alpha-fetoprotein transgenes in the livers of adult mice

scientific article published on September 1, 1992

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

article

Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon

scientific article

Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression

scientific article published on 22 September 2005

Vemurafenib Inhibits Active PTK6 in PTEN-null Prostate Tumor Cells

scientific article published on 29 March 2019

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