List of works - Louise Warnich

A call for pharmacogenovigilance and rapid falsification in the age of big data: why not first road test your biomarker?

scientific article published on 29 October 2014

A microsatellite-based index map of human chromosome 11

scientific article published on 01 July 1993

A newStyl RFLP and haplotypes with theHindIII RFLP at the D8S5 (TL11) locus ⬇️

scientific article published on September 11, 1991

A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups

article

A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia.

scientific article

An Appeal to the Global Health Community for a Tripartite Innovation: An "Essential Diagnostics List," "Health in All Policies," and "See-Through 21(st) Century Science and Ethics".

scientific article

An Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016.

scientific article published in April 2016

An anonymous DNA probe E141 (D5S99) on chromosome 5 detects an EcoRI polymorphism.

scientific article published on June 1990

An anonymous DNA probe E20 [D4S143] on chromosome 4 detects a TaqI polymorphism

scientific article published on February 1990

An anonymous DNA probe M7 (D7S422) on chromosome 7 associated with two RFLP's

scientific article published on September 1990

An anonymous human single copy genomic clone (D8S5) (TL11) on chromosome 8 identifies a moderately frequent RFLP

scientific article

An anonymous human single copy genomic clone, D11S29 (L7) at 11q23, identifies a moderately frequent RFLP

scientific article published on February 1986

Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload

scientific article

Analysis of pharmacogenetic traits in two distinct South African populations

scientific article

Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.

scientific article published in August 2005

Analysis of viral and genetic factors in South African patients with multiple sclerosis.

scientific article published on 22 July 2006

Anonymous DNA segment H33 [D6S42] on chromosome 6 associated with 2 RFLPs

scientific article published on January 1989

Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population

scientific article published on 12 January 2007

Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort.

scientific article

Association of functional polymorphisms of SLC11A1 with risk of esophageal cancer in the South African Colored population

scientific article published in May 2005

Association study in three different populations between the GPR88 gene and major psychoses

scientific article published on 12 December 2013

Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).

scientific article published on 20 March 2014

Biotechnology Innovators To Convene in Cape Town, South Africa: Pharmacogenetics and Precision Medicine Conference (April 7-9, 2016).

scientific article

CYP2B66 and CYP2B618 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women

scientific article published on 13 December 2015

Characterization of the genetic profile of CYP2C19 in two South African populations.

scientific article published on August 2010

Characterization of the genetic variation present in CYP3A4 in three South African populations.

scientific article published on 18 February 2013

Chromosome 22q11 in a Xhosa schizophrenia population.

scientific article published on 23 February 2012

Considerations for rare variants in drug metabolism genes and the clinical implications

scientific article published on 28 March 2014

Cytochrome P450 pharmacogenetics in African populations.

scientific article published on 16 April 2013

DNA methylation and antipsychotic treatment mechanisms in schizophrenia: Progress and future directions

scientific article published on 7 October 2017

Detection of a frequent polymorphism in exon 10 of the low-density lipoprotein receptor gene ⬇️

scientific article published on May 1, 1992

Dinucleotide repeat polymorphism at the D5S99 locus on chromosome 5q33?34

scientific article published on 01 October 1995

Editorial: CPPM 2013 Onward: Building a Socio-Technical GPS for Global Personalized Medicine – A Welcome to Editors-In-Chief Adrian LLerena (Spain) and Ross A. McKinnon (Australia)

article

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population

scientific article published in July 2010

End of the Beginning and Public Health Pharmacogenomics: Knowledge in 'Mode 2' and P5 Medicine

scientific article published in January 2012

Evaluation of predictiveCYP2C19genotyping assays relative to measured phenotype in a South African cohort

scientific article published on 05 August 2015

Expression of the SLC11A1 (NRAMP1) 5'-(GT)n repeat: opposite effect in the presence of -237C-->T.

scientific article published on July 2004

Extended haplotype studies in South African and Dutch variegate porphyria families carrying the recurrent p.R59W mutation confirm a common ancestry

scientific article published on February 2012

Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms

scientific article

Forward Look: Tenth Anniversary of the Human Genome Sequence and 21 Century Postgenomics Global Health - A Close Up on Africa and Women's Health

scientific article published on September 2011

Gene symbol: SLC40A1. Disease: primary iron overload

scientific article published in December 2005

Genetic diversity of woolly apple aphid Eriosoma lanigerum (Hemiptera: Aphididae) populations in the Western Cape, South Africa.

scientific article

Genetic research, behavioural science, and child and adolescent mental health in South Africa: an important new agenda

scientific article

H3Africa and the African life sciences ecosystem: building sustainable innovation

scientific article

Haplotype analysis excludes the functional protoporphyrinogen oxidase promoter polymorphism -1081G>A as a modifying factor in the clinical expression of variegate porphyria

scientific article

Highly informative dinucleotide repeat polymorphism at the D11S29 locus on chromosome 11q23 ⬇️

scientific article published on May 1, 1992

Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene

scientific article

Identification of three mutations and associated haplotypes in the protoporphyrinogen oxidase gene in South African families with variegate porphyria

article

In silico promoters: modelling of cis-regulatory context facilitates target predictio

scientific article published on 24 May 2008

Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study

scientific article

Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1

scientific article published on 25 September 2012

Lack of clinical manifestation of hereditary haemochromatosis in South African patients with multiple sclerosis

scientific article published on 19 July 2006

Linkage disequilibrium analysis in a recently founded population: evaluation of the variegate porphyria founder in South African Afrikaners

scientific article published in May 1998

Mapping of the variegate porphyria (VP) gene: contradictory evidence for linkage between VP and microsatellite markers at chromosome 14q32

scientific article published on 01 May 1996

Modification of the association between antipsychotic treatment response and childhood adversity by MMP9 gene variants in a first-episode schizophrenia cohort.

scientific article published on 7 February 2018

Molecular analysis reveals a high mutation frequency in the first untranslated exon of the PPOX gene and largely excludes variegate porphyria in a subset of clinically affected Afrikaner families

scientific article published in October 1998

Molecular diagnosis of hereditary hemochromatosis: application of a newly-developed reverse-hybridization assay in the South African population

scientific article published in April 2004

Next-generation sequencing of pharmacogenes

scientific article published on 01 December 2013

Overrepresentation of the founder PPOX gene mutation R59W in a South African patient with severe clinical manifestation of porphyria.

scientific article published in January 2005

Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients

scientific article

Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

scientific article published on September 2011

Population genetic structure of economically important Tortricidae (Lepidoptera) in South Africa: a comparative analysis

scientific article published on 27 November 2009

Predictors of abnormal involuntary movement in an african schizophrenia population

scientific article published in January 2008

Psychiatric genetics in South Africa: cutting a rough diamond.

scientific article

Public Health Pharmacogenomics and the Design Principles for Global Public Goods - Moving Genomics to Responsible Innovation

scientific article published on March 2013

Reactions, beliefs and concerns associated with providing hair specimens for medical research among a South African sample: a qualitative approach

scientific article published on November 2012

Regional localization of α-galactosidase ( GLA ) to Xpter→q22, hexosaminidase B ( HEXB ) to 5q13→qter, and arylsulfatase B ( ARSB ) to5pter→q13

scientific article published on 01 January 1984

Significance of novel endothelin-B receptor gene polymorphisms in Hirschsprung's disease: predominance of a novel variant (561C/T) in patients with co-existing Down's syndrome

article

Single nucleotide polymorphisms of the protoporphyrinogen oxidase gene: inter-population heterogeneity of allelic variation

scientific article published in August 2001

Special issue "OMICS IN AFRICA": power to the people--moving 21st century integrative biology from lab to village to innovation ecosystems.

scientific article

The -237C-->T promoter polymorphism of the SLC11A1 gene is associated with a protective effect in relation to inflammatory bowel disease in the South African population.

scientific article

The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder

scientific article published on 2 March 2018

The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients.

scientific article

The molecular basis and diagnosis of familial hypercholesterolaemia in South African Afrikaners

scientific article published in May 1991

Three allele RFLP identified by an anonymous sequence on chromosome 2, E135 [D2S62]

scientific article published on January 1989

Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications

scientific article

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

scientific article published on 16 September 2016

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

scientific article (publication date: 2014)

Towards an Ecology of Collective Innovation: Human Variome Project (HVP), Rare Disease Consortium for Autosomal Loci (RaDiCAL) and Data-Enabled Life Sciences Alliance (DELSA)

scientific article (publication date: December 2011)

Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders

scientific article

Two novel point mutations causing receptor-negative familial hypercholesterolemia in a South African Indian homozygote.

scientific article

Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort

scientific article published on 22 July 2018

Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications.

scientific article published in December 2011

Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.

scientific article published on 12 December 2017

List of works by Louise Warnich

A call for pharmacogenovigilance and rapid falsification in the age of big data: why not first road test your biomarker?

A microsatellite-based index map of human chromosome 11

A newStyl RFLP and haplotypes with theHindIII RFLP at the D8S5 (TL11) locus ⬇️

A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups

A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia.

An Appeal to the Global Health Community for a Tripartite Innovation: An "Essential Diagnostics List," "Health in All Policies," and "See-Through 21(st) Century Science and Ethics".

An Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016.

An anonymous DNA probe E141 (D5S99) on chromosome 5 detects an EcoRI polymorphism.

An anonymous DNA probe E20 [D4S143] on chromosome 4 detects a TaqI polymorphism

An anonymous DNA probe M7 (D7S422) on chromosome 7 associated with two RFLP's

An anonymous human single copy genomic clone (D8S5) (TL11) on chromosome 8 identifies a moderately frequent RFLP

An anonymous human single copy genomic clone, D11S29 (L7) at 11q23, identifies a moderately frequent RFLP

Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload

Analysis of pharmacogenetic traits in two distinct South African populations

Analysis of the three common mutations in the CARD15 gene (R702W, G908R and 1007fs) in South African colored patients with inflammatory bowel disease.

Analysis of viral and genetic factors in South African patients with multiple sclerosis.

Anonymous DNA segment H33 [D6S42] on chromosome 6 associated with 2 RFLPs

Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population

Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort.

Association of functional polymorphisms of SLC11A1 with risk of esophageal cancer in the South African Colored population

Association study in three different populations between the GPR88 gene and major psychoses

Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).

Biotechnology Innovators To Convene in Cape Town, South Africa: Pharmacogenetics and Precision Medicine Conference (April 7-9, 2016).

CYP2B6*6 and CYP2B6*18 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women

Characterization of the genetic profile of CYP2C19 in two South African populations.

Characterization of the genetic variation present in CYP3A4 in three South African populations.

Chromosome 22q11 in a Xhosa schizophrenia population.

Considerations for rare variants in drug metabolism genes and the clinical implications

Cytochrome P450 pharmacogenetics in African populations.

DNA methylation and antipsychotic treatment mechanisms in schizophrenia: Progress and future directions

Detection of a frequent polymorphism in exon 10 of the low-density lipoprotein receptor gene ⬇️

Dinucleotide repeat polymorphism at the D5S99 locus on chromosome 5q33?34

Editorial: CPPM 2013 Onward: Building a Socio-Technical GPS for Global Personalized Medicine – A Welcome to Editors-In-Chief Adrian LLerena (Spain) and Ross A. McKinnon (Australia)

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population

End of the Beginning and Public Health Pharmacogenomics: Knowledge in 'Mode 2' and P5 Medicine

Evaluation of predictiveCYP2C19genotyping assays relative to measured phenotype in a South African cohort

Expression of the SLC11A1 (NRAMP1) 5'-(GT)n repeat: opposite effect in the presence of -237C-->T.

Extended haplotype studies in South African and Dutch variegate porphyria families carrying the recurrent p.R59W mutation confirm a common ancestry

Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms

Forward Look: Tenth Anniversary of the Human Genome Sequence and 21 Century Postgenomics Global Health - A Close Up on Africa and Women's Health

Gene symbol: SLC40A1. Disease: primary iron overload

Genetic diversity of woolly apple aphid Eriosoma lanigerum (Hemiptera: Aphididae) populations in the Western Cape, South Africa.

Genetic research, behavioural science, and child and adolescent mental health in South Africa: an important new agenda

H3Africa and the African life sciences ecosystem: building sustainable innovation

Haplotype analysis excludes the functional protoporphyrinogen oxidase promoter polymorphism -1081G>A as a modifying factor in the clinical expression of variegate porphyria

Highly informative dinucleotide repeat polymorphism at the D11S29 locus on chromosome 11q23 ⬇️

Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene

Identification of three mutations and associated haplotypes in the protoporphyrinogen oxidase gene in South African families with variegate porphyria

In silico promoters: modelling of cis-regulatory context facilitates target predictio

Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study

Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1

Lack of clinical manifestation of hereditary haemochromatosis in South African patients with multiple sclerosis

Linkage disequilibrium analysis in a recently founded population: evaluation of the variegate porphyria founder in South African Afrikaners

Mapping of the variegate porphyria (VP) gene: contradictory evidence for linkage between VP and microsatellite markers at chromosome 14q32

Modification of the association between antipsychotic treatment response and childhood adversity by MMP9 gene variants in a first-episode schizophrenia cohort.

Molecular analysis reveals a high mutation frequency in the first untranslated exon of the PPOX gene and largely excludes variegate porphyria in a subset of clinically affected Afrikaner families

Molecular diagnosis of hereditary hemochromatosis: application of a newly-developed reverse-hybridization assay in the South African population

Next-generation sequencing of pharmacogenes

Overrepresentation of the founder PPOX gene mutation R59W in a South African patient with severe clinical manifestation of porphyria.

Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients

Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

Population genetic structure of economically important Tortricidae (Lepidoptera) in South Africa: a comparative analysis

Predictors of abnormal involuntary movement in an african schizophrenia population

Psychiatric genetics in South Africa: cutting a rough diamond.

Public Health Pharmacogenomics and the Design Principles for Global Public Goods - Moving Genomics to Responsible Innovation

Reactions, beliefs and concerns associated with providing hair specimens for medical research among a South African sample: a qualitative approach

Regional localization of α-galactosidase ( GLA ) to Xpter→q22, hexosaminidase B ( HEXB ) to 5q13→qter, and arylsulfatase B ( ARSB ) to5pter→q13

Significance of novel endothelin-B receptor gene polymorphisms in Hirschsprung's disease: predominance of a novel variant (561C/T) in patients with co-existing Down's syndrome

Single nucleotide polymorphisms of the protoporphyrinogen oxidase gene: inter-population heterogeneity of allelic variation

Special issue "OMICS IN AFRICA": power to the people--moving 21st century integrative biology from lab to village to innovation ecosystems.

The -237C-->T promoter polymorphism of the SLC11A1 gene is associated with a protective effect in relation to inflammatory bowel disease in the South African population.

The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder

The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients.

The molecular basis and diagnosis of familial hypercholesterolaemia in South African Afrikaners

Three allele RFLP identified by an anonymous sequence on chromosome 2, E135 [D2S62]

Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

Towards an Ecology of Collective Innovation: Human Variome Project (HVP), Rare Disease Consortium for Autosomal Loci (RaDiCAL) and Data-Enabled Life Sciences Alliance (DELSA)

CYP2B66 and CYP2B618 Predict Long-Term Efavirenz Exposure Measured in Hair Samples in HIV-Positive South African Women