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List of works by Edward A. Clark

17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells

scientific article

A CD40 Bridge between Innate and Adaptive Immunity

scientific article published on 01 June 2003

A Short History of the B-Cell-Associated Surface Molecule CD40

scientific article

Activation of macaque T cells and B cells with agonistic monoclonal antibodies

scholarly article by Edward A. Clark & Kevin E. Draves published 1987 in European Journal of Immunology

Activation of natural killer (NK) cells in vivo with H-2 and non-H-2 alloantigens

scientific article published on 01 January 1981

Adhesion-mediating molecules of human monocytes

scientific article published in May 1988

Amplification of the immune response by agonistic antibodies

scientific article published in September 1986

Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway

scientific article

Antibodies to murine CD40 stimulate normal B lymphocytes but inhibit proliferation of B lymphoma cells.

scientific article published on December 1993

B cells with the guts to switch

scholarly article by Edward A. Clark & Kevin L. Otipoby published July 2001 in Nature Immunology

B-cell selection and the development of autoantibodies

scientific article published on 2 November 2012

BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus

scientific article published on 07 February 2020

BAFF and LPS cooperate to induce B cells to become susceptible to CD95/Fas-mediated cell death

scientific article published on 01 April 2007

BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway

scientific article

BCR-induced superoxide negatively regulates B-cell proliferation and T-cell-independent type 2 Ab responses

scientific article

Baboon T cell lymphomas expressing the B cell-associated surface proteins CD40 and Bgp95.

scientific article published in May 1992

Bim regulates BCR-induced entry of B cells into the cell cycle

scientific journal article

Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis.

scientific article

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1

scientific article (publication date: November 2003)

CD Antigens 2001

CD Antigens 2001

CD antigens 2001

scientific article published on 01 December 2001

CD antigens 2002

scientific article published on 01 May 2002

CD nomenclature for mouse antigens?

scientific article published in January 1987

CD150 regulates JNK1/2 activation in normal and Hodgkin's lymphoma B cells

scientific article

CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells

CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation

scientific article

CD22 is required for formation of memory B cell precursors within germinal centers

scientific article

CD22 is required for protection against West Nile virus Infection

scientific article published on 9 January 2013

CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1

scientific article (publication date: 23 November 2001)

CD4 and CD8 T cells from SIV-infected macaques have defective signaling responses after perturbation of either CD3 or CD2 receptors

scientific article published on January 1990

CD40: A cytokine receptor in search of a ligand ⬇️

scientific article published on July 1, 1990

CDw40 and BLCa-specific monoclonal antibodies detect two distinct molecules which transmit progression signals to human B lymphocytes

scholarly article by Edward A. Clark et al published March 1988 in European Journal of Immunology

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

scientific article

Cell-cell interactions that regulate the development of B-lineage cells

scientific article published on April 1994

Characteristics and genetic control of NK-cell-mediated cytotoxicity activated by naturally acquired infection in the mouse ⬇️

scientific article published on November 15, 1979

Characterization of molecular components associated with surface immunoglobulin M in human B lymphocytes: presence of tyrosine and serine/threonine protein kinases

scientific article published on August 1992

Conservation of HLA class I private epitopes in macaques

scientific article published on 01 January 1988

Controlling immune responses by targeting antigens to dendritic cell subsets and B cells

scientific article

Corrigendum to “The role of CD40 and CD154/CD40L in dendritic cells” [Seminars Immunol. 21 (2010) 265–272]

scholarly article published in Seminars in Immunology

Cytotoxic and fluorescent assays for thymocyte subpopulations differing in surface thy-1 level ⬇️

scientific article published on September 1, 1979

Decrease in glomerulonephritis and Th1-associated autoantibody production after progesterone treatment in NZB/NZW mice.

scientific article published in June 2009

Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α- dendritic cell subset

scientific article published on 6 December 2011

Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production

scientific article

Detection of lymphocyte subsets using three-color/single-laser flow cytometry and the fluorescent dye Peridinin chlorophyll-a protein ⬇️

scientific article published on September 1, 1991

Development of lymphocyte subsets in pigtailed macaques

scientific article published on 01 January 1988

Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase.

scientific article

Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria

scientific article

Differential expression of CD180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes

article

Differential expression of Epstein-Barr virus membrane antigens defined with monoclonal antibodies

scientific article

EVALUATION OF BELZER AND COLLINS KIDNEY-PRESERVATION METHODS

scientific article published in The Lancet

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

scientific article

Evolution of HLA class I epitopes defined by murine monoclonal antibodies: Distribution in macaques

article

Evolution of epitopes on human and nonhuman primate lymphocyte cell surface antigens

scientific article published on January 1983

Expression and function of the adaptor protein Gads in murine B cells.

scientific article

Expression of the c-myc proto-oncogene is essential for HIV-1 infection in activated T cells.

scientific article

Extrafollicular B cell activation by marginal zone dendritic cells drives T cell-dependent antibody responses

scientific article

Fluctuations of CD4+ T-cell subsets in remitting-relapsing multiple sclerosis

scientific article

Fluctuations of T- and B-cell subsets in basic protein-induced experimental allergic encephalomyelitis (EAE) in long-tailed macaques

scientific article published on 01 July 1987

Formation of simian immunodeficiency virus long terminal repeat circles in resting T cells requires both T cell receptor- and IL-2-dependent activation

scientific article

Gads-deficient thymocytes are blocked at the transitional single positive CD4+ stage

scientific article published on May 2009

Generation of phosphatidic acid and diacylglycerols following ligation of surface immunoglobulin in human B lymphocytes: potential role in PKC activation

scientific article published on May 1, 1992

Genetic polymorphism of C3 in Papio and Macaca species

scientific article published on 01 October 1982

Genetics of graft-versus-host reactions

article

Genetics of graft-versus-host reactions (GVHR)

article

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

scientific article

Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40.

scientific article published on August 1990

Immunity to MCA-induced rat sarcomas: Analysis ofin vivo andin vitro results

article

In vivo administration of anti-CD4 monoclonal antibody prolongs survival in longtailed macaques with experimental allergic encephalomyelitis

scientific article

Induction of target antigens and conversion to susceptible phenotype of NK-cell-resistant lymphoid cell line

scientific article published in November 1981

Interleukin 2 stimulates serine phosphorylation of CD45 in CTLL-2.4 cells

scientific article published on April 1991

Intracellular TCR-signaling pathway: novel markers for lymphoma diagnosis and potential therapeutic targets.

scientific article

Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor.

scientific article published in October 1998

Isolation and Characterization of Macaque Dendritic Cells from CD34+ Bone Marrow Progenitors

article

Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells

scientific article

Macaque CD4+ T-cell subsets: influence of activation on infection by simian immunodeficiency viruses (SIV)

scientific article published on March 1, 1992

Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.

scientific article published on 16 January 2003

Modulation and function of caspase pathways in B lymphocytes

scientific article published on February 2004

Mutations in mice that influence natural killer (NK) cell activity

article published in 1981

Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19

scientific article

Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses

scientific article

Nitric oxide regulates BAFF expression and T cell-independent antibody responses

scientific article published on 20 June 2014

Osteoprotegerin Is an αvβ3-induced, NF-κB-dependent Survival Factor for Endothelial Cells

scientific article published in Journal of Biological Chemistry

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

scientific article published on 21 October 2013

Polygenic Autoimmune Traits: Lyn, CD22, and SHP-1 Are Limiting Elements of a Biochemical Pathway Regulating BCR Signaling and Selection ⬇️

scientific article published on April 1, 1998

Polypeptides on human B lymphocytes associated with cell activation

scientific article published on 01 May 1986

Production and characterization of cytotoxic Thy-1 antibody-secreting hybrid cell lines. Detection of T cell subsets

scientific article published on November 1979

Properties of mouse CD40: Cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies

scholarly article by Jhagvaral Hasboldu et al published August 1994 in European Journal of Immunology

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization

scientific article published on 27 November 2017

Reactivity patterns of class I HLA monoclonal antibodies that distinguish three species of macaques

scientific article published on 01 January 1990

Regulation of B lymphocytes by dendritic cells.

scientific article

Regulation of B-cell entry into the cell cycle

scientific article published on August 2008

Regulation of B-cell fate by antigen-receptor signals

scientific article

Regulation of dendritic cell survival and cytokine production by osteoprotegerin

scientific article published on 29 July 2009

Regulation of dendritic cells by female sex steroids: relevance to immunity and autoimmunity

scientific article published on September 2007

Regulation of lymphocyte activation by the cell-surface molecule CD22

scientific article published on 01 September 1994

Relative size and evolution of the germline repertoire of T-cell receptor beta-chain gene segments in nonhuman primates

scientific article published in January 1995

Reply

article published in 1989

Report from Vienna: in search of all surface molecules expressed on human leukocytes

scientific article published in July 1989

Resistance ofH-2 heterozygous mice to parental tumors

Rewiring of sIgM-mediated intracellular signaling through the CD180 Toll-like receptor

scientific article published on 14 January 2015

Role for CD40-mediated activation of c-Rel and maintenance of c-myc RNA levels in mitigating anti-IgM-induced growth arrest

scientific article published on October 1997

Role of dendritic and follicular dendritic cells in HIV infection and pathogenesis

scientific article published on August 1997

STALing B cell responses with CD22.

scientific article published on 03 June 2013

Selective loss of a subset of T helper cells in active multiple sclerosis.

scientific article

Signaling through CD19, Fc receptors or transforming growth factor-β: each inhibits the activation of resting human B cells differently

scholarly article by Thomas B. Barrett et al published May 1990 in European Journal of Immunology

Spi-1 and Spi-B control the expression of the Grap2 gene in B cells

scientific article

Splenic macrophages are required for protective innate immunity against West Nile virus

scientific article

Surface phenotype and function of tonsillar germinal center and mantle zone B cell subsets

scientific article published on 01 January 1986

Survival niches: B cells get MIFed as well as BAFFled by dendritic cells

scientific article published on 27 May 2008

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt.

scientific article published on October 1999

T-Cell Alterations in Late Postpoliomyelitis

scientific article published on 01 May 1989

Targeting Antigens to CD180 but Not CD40 Programs Immature and Mature B Cell Subsets to Become Efficient APCs

scientific article published on 04 September 2019

Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling

scientific article

Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance

scientific article

Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory

scientific article published on 09 September 2013

The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival

scientific article

The CD40-Inducible Bcl-2 Family Member A1 Protects B Cells from Antigen Receptor-Mediated Apoptosis

article

The Plasticity of Newly Formed B Cells

scientific article published on 01 December 2019

The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness

scientific article published on 26 July 2012

The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism

scientific article

The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells

scientific article

The dual-function CD150 receptor subfamily: the viral attraction

scientific article

The intracellular progesterone receptor regulates CD4+ T cells and T cell-dependent antibody responses

scientific article published on 10 January 2013

The major histocompatibility complex, MnLA, of pigtailed Macaques: Definition of fifteen specificities

scientific article published on 01 April 1989

The role of CD40 and CD154/CD40L in dendritic cells

scientific article published on 12 June 2009

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection

scientific article published in July 1994

Therapeutic uses of agonistic monoclonal antibodies to human lymphocyte cell-surface molecules

Transient immune deficiency in patients with acute Epstein-Barr virus infection

scientific article

Triggering of neoplastic B cellsvia surface IgM and the cell surface antigens CD20 and CDw40. Responses differ from normal blood B cells and are restricted to certain morphologic subsets

article

Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34(+) progenitor cells during differentiation into antigen presenting cells

scientific article published on 24 September 2001

Viral and cellular gene expression in CD4+ human lymphoid cell lines infected by the simian immunodeficiency virus, SIV/Mne

scientific article published on July 1991

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