List of works - Hirokazu Yagi

A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex

scientific article

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan

scientific journal article

ATP hydrolysis by KaiC promotes its KaiA binding in the cyanobacterial circadian clock system

scientific article published on 03 June 2019

Alteration of a recombinant protein N-glycan structure in silkworms by partial suppression of N-acetylglucosaminidase gene expression

scientific article published on 25 May 2017

An Archaeal Homolog of Proteasome Assembly Factor Functions as a Proteasome Activator

scientific article

Analysis of N-glycans in embryonated chicken egg chorioallantoic and amniotic cells responsible for binding and adaptation of human and avian influenza viruses.

scientific article

Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein

scientific article

Backbone and side chain 1H, 13C, and 15N assignments of the ubiquitin-like domain of human HOIL-1L, an essential component of linear ubiquitin chain assembly complex

scientific article

Backbone ¹H, ¹³C and ¹⁵N assignments of yeast Ump1, an intrinsically disordered protein that functions as a proteasome assembly chaperone

scientific article published on 25 September 2013

Comparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines : HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study

scientific article published on 28 October 2015

Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1

scientific article

Comparison of the N-linked glycosylation of human beta1,3-N-acetylglucosaminyltransferase 2 expressed in insect cells and silkworm larvae

scientific article published on 21 June 2009

Cooperative Binding of KaiB to the KaiC Hexamer Ensures Accurate Circadian Clock Oscillation in Cyanobacteria

scientific article published on 13 September 2019

Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related β-prism fold

scientific article

Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer

scientific article published on 31 August 2018

Development of structural analysis of sulfated N-glycans by multidimensional high performance liquid chromatography mapping methods

scientific article published on 15 June 2005

Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis.

scientific article published on 27 December 2005

Direct Mapping of Additional Modifications on Phosphorylated O-glycans of α-Dystroglycan by Mass Spectrometry Analysis in Conjunction with Knocking Out of Causative Genes for Dystroglycanopathy

scientific article published on 6 September 2016

Disassembly of the self-assembled, double-ring structure of proteasome α7 homo-tetradecamer by α6.

scientific article

Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis

scientific article published in 2018

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

scientific article published on 17 February 2020

Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.

scientific article published on 10 June 2015

Functional roles of glycoconjugates in the maintenance of stemness and differentiation process of neural stem cells

scientific article published on 27 June 2016

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain

scientific article published on 13 March 2019

Glycan structure and serum half-life of recombinant CTLA4Ig, an immunosuppressive agent, expressed in suspension-cultured rice cells with coexpression of human β1,4-galactosyltransferase and human CTLA4Ig.

scientific article published on 14 May 2015

Glycobiological study of adult Opisthorchis viverrini: characterization of N-linked oligosaccharides

scientific article published on 10 March 2006

Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy.

scientific article

Glycomic analyses of glycoproteins in bile and serum during rat hepatocarcinogenesis.

scientific article

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells.

scientific article

Human IgG1 expression in silkworm larval hemolymph using BmNPV bacmids and its N-linked glycan structure

scientific article published on 15 October 2008

IgEb immune complexes activate macrophages through FcgammaRIV binding

scientific journal article

Impaired O-linked N-acetylglucosaminylation in the endoplasmic reticulum by mutated epidermal growth factor (EGF) domain-specific O-linked N-acetylglucosamine transferase found in Adams-Oliver syndrome.

scientific article

Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors

scientific article

Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor

scientific article published on 13 March 2020

Improved secretion of molecular chaperone-assisted human IgG in silkworm, and no alterations in their N-linked glycan structures

scientific article published on January 2010

Involvement of beta1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells.

scientific article

Kinetic Asymmetry of Subunit Exchange of Homooligomeric Protein as Revealed by Deuteration-Assisted Small-Angle Neutron Scattering ⬇️

scientific article published on October 19, 2011

Lectin microarray analysis of isolated polysaccharides from Sasa veitchii.

scientific article published on 21 June 2017

Lewis X-Carrying Neoglycolipids Evoke Selective Apoptosis in Neural Stem Cells.

scientific article

Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the Notch signaling pathway.

scientific article

Mutational and Combinatorial Control of Self-Assembling and Disassembling of Human Proteasome α Subunits. ⬇️

scientific article published on 9 May 2019

N-Glycan Modification of a Recombinant Protein via Coexpression of Human Glycosyltransferases in Silkworm Pupae

scientific article

N-Glycosylation profiling of turtle egg yolk: expression of galabiose structure

scientific article published on 11 December 2009

N-glycans from porcine trachea and lung: predominant NeuAcα2-6Gal could be a selective pressure for influenza variants in favor of human-type receptor

scientific article (publication date: 9 February 2011)

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods

scientific article published on 07 October 2019

NMR characterization of intramolecular interaction of osteopontin, an intrinsically disordered protein with cryptic integrin-binding motifs

scientific article published on 10 February 2010

NMR-based structural validation of therapeutic antibody produced in Nicotiana benthamiana.

scientific article published on 18 February 2015

Neural complex-specific expression of xylosyl N-glycan in Ciona intestinalis

scientific article published on 3 December 2007

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

scientific article published on 24 December 2019

Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome α-ring formation.

scientific article published in July 2014

Self-recognition of high-mannose type glycans mediating adhesion of embryonal fibroblasts.

scientific article

Silkworm Pupae Function as Efficient Producers of Recombinant Glycoproteins with Stable-Isotope Labeling

scientific article published on 26 October 2020

Silkworm expression and sugar profiling of human immune cell surface receptor, KIR2DL1.

scientific article

Site-specific N-glycosylation analysis of soluble Fcγ receptor IIIb in human serum.

scientific article published on 9 February 2018

Spatial arrangement and functional role of α subunits of proteasome activator PA28 in hetero-oligomeric form

scientific article published on 29 January 2013

Stable isotope labeling of glycoprotein expressed in silkworms using immunoglobulin G as a test molecule

scientific article published on 23 April 2015

Structural and molecular basis of carbohydrate-protein interaction systems as potential therapeutic targets

scientific article published on 01 January 2011

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans ⬇️

scientific article published on November 1, 2011

Structural basis for proteasome formation controlled by an assembly chaperone nas2

scientific article

Structural heterogeneity of glycoform of alpha-1 Acid glycoprotein in alcoholic cirrhosis patients

scientific article

Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation

scientific article published on 30 January 2020

Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae

scientific article published on 5 June 2009

Temperature-dependent isologous Fab-Fab interaction that mediates cryocrystallization of a monoclonal immunoglobulin G

scientific article published on 01 November 2004

The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III

scientific article published on 16 August 2019

The expression of sialylated high-antennary N-glycans in edible bird's nest.

scientific article published on 31 March 2008

The quail and chicken intestine have sialyl-galactose sugar chains responsible for the binding of influenza A viruses to human type receptors.

scientific article

pH-Dependent Assembly and Segregation of the Coiled-Coil Segments of Yeast Putative Cargo Receptors Emp46p and Emp47p

scientific article

List of works by Hirokazu Yagi

A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex

AGO61-dependent GlcNAc modification primes the formation of functional glycans on α-dystroglycan

ATP hydrolysis by KaiC promotes its KaiA binding in the cyanobacterial circadian clock system

Alteration of a recombinant protein N-glycan structure in silkworms by partial suppression of N-acetylglucosaminidase gene expression

An Archaeal Homolog of Proteasome Assembly Factor Functions as a Proteasome Activator

Analysis of N-glycans in embryonated chicken egg chorioallantoic and amniotic cells responsible for binding and adaptation of human and avian influenza viruses.

Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein

Backbone and side chain 1H, 13C, and 15N assignments of the ubiquitin-like domain of human HOIL-1L, an essential component of linear ubiquitin chain assembly complex

Backbone ¹H, ¹³C and ¹⁵N assignments of yeast Ump1, an intrinsically disordered protein that functions as a proteasome assembly chaperone

Comparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines : HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study

Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1

Comparison of the N-linked glycosylation of human beta1,3-N-acetylglucosaminyltransferase 2 expressed in insect cells and silkworm larvae

Cooperative Binding of KaiB to the KaiC Hexamer Ensures Accurate Circadian Clock Oscillation in Cyanobacteria

Crystal structures of human secretory proteins ZG16p and ZG16b reveal a Jacalin-related β-prism fold

Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer

Development of structural analysis of sulfated N-glycans by multidimensional high performance liquid chromatography mapping methods

Differential glycosylation of polyclonal IgG, IgG-Fc and IgG-Fab isolated from the sera of patients with ANCA-associated systemic vasculitis.

Direct Mapping of Additional Modifications on Phosphorylated O-glycans of α-Dystroglycan by Mass Spectrometry Analysis in Conjunction with Knocking Out of Causative Genes for Dystroglycanopathy

Disassembly of the self-assembled, double-ring structure of proteasome α7 homo-tetradecamer by α6.

Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.

Functional roles of glycoconjugates in the maintenance of stemness and differentiation process of neural stem cells

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain

Glycan structure and serum half-life of recombinant CTLA4Ig, an immunosuppressive agent, expressed in suspension-cultured rice cells with coexpression of human β1,4-galactosyltransferase and human CTLA4Ig.

Glycobiological study of adult Opisthorchis viverrini: characterization of N-linked oligosaccharides

Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy.

Glycomic analyses of glycoproteins in bile and serum during rat hepatocarcinogenesis.

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells.

Human IgG1 expression in silkworm larval hemolymph using BmNPV bacmids and its N-linked glycan structure

IgEb immune complexes activate macrophages through FcgammaRIV binding

Impaired O-linked N-acetylglucosaminylation in the endoplasmic reticulum by mutated epidermal growth factor (EGF) domain-specific O-linked N-acetylglucosamine transferase found in Adams-Oliver syndrome.

Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors

Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor

Improved secretion of molecular chaperone-assisted human IgG in silkworm, and no alterations in their N-linked glycan structures

Involvement of beta1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells.

Kinetic Asymmetry of Subunit Exchange of Homooligomeric Protein as Revealed by Deuteration-Assisted Small-Angle Neutron Scattering ⬇️

Lectin microarray analysis of isolated polysaccharides from Sasa veitchii.

Lewis X-Carrying Neoglycolipids Evoke Selective Apoptosis in Neural Stem Cells.

Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the Notch signaling pathway.

Mutational and Combinatorial Control of Self-Assembling and Disassembling of Human Proteasome α Subunits. ⬇️

N-Glycan Modification of a Recombinant Protein via Coexpression of Human Glycosyltransferases in Silkworm Pupae

N-Glycosylation profiling of turtle egg yolk: expression of galabiose structure

N-glycans from porcine trachea and lung: predominant NeuAcα2-6Gal could be a selective pressure for influenza variants in favor of human-type receptor

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods

NMR characterization of intramolecular interaction of osteopontin, an intrinsically disordered protein with cryptic integrin-binding motifs

NMR-based structural validation of therapeutic antibody produced in Nicotiana benthamiana.

Neural complex-specific expression of xylosyl N-glycan in Ciona intestinalis

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome α-ring formation.

Self-recognition of high-mannose type glycans mediating adhesion of embryonal fibroblasts.

Silkworm Pupae Function as Efficient Producers of Recombinant Glycoproteins with Stable-Isotope Labeling

Silkworm expression and sugar profiling of human immune cell surface receptor, KIR2DL1.

Site-specific N-glycosylation analysis of soluble Fcγ receptor IIIb in human serum.

Spatial arrangement and functional role of α subunits of proteasome activator PA28 in hetero-oligomeric form

Stable isotope labeling of glycoprotein expressed in silkworms using immunoglobulin G as a test molecule

Structural and molecular basis of carbohydrate-protein interaction systems as potential therapeutic targets

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans ⬇️

Structural basis for proteasome formation controlled by an assembly chaperone nas2

Structural heterogeneity of glycoform of alpha-1 Acid glycoprotein in alcoholic cirrhosis patients

Supramolecular tholos-like architecture constituted by archaeal proteins without functional annotation

Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae

Temperature-dependent isologous Fab-Fab interaction that mediates cryocrystallization of a monoclonal immunoglobulin G

The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III

The expression of sialylated high-antennary N-glycans in edible bird's nest.

The quail and chicken intestine have sialyl-galactose sugar chains responsible for the binding of influenza A viruses to human type receptors.

pH-Dependent Assembly and Segregation of the Coiled-Coil Segments of Yeast Putative Cargo Receptors Emp46p and Emp47p