List of works - Leendert A Trouw

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis

scientific article

A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

scientific article

A mutation in factor I that is strongly associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

A role for mannose-binding lectin dysfunction in generation of autoantibodies in systemic lupus erythematosus

scientific article published on 12 October 2004

Activation of the lectin pathway in murine lupus nephritis

scientific article published on 01 April 2005

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

scientific article

Analysis of binding sites on complement factor I that are required for its activity

scientific article

Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes.

scientific article published on September 2004

Anti-C1q autoantibodies in murine lupus nephritis

scientific article published on 01 January 2004

Anti-C1q autoantibodies, novel tests, and clinical consequences

scientific article published on 14 May 2013

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

scientific article published on 8 May 2014

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

scientific article published on 13 December 2013

Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

scientific article published in April 2013

Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.

scientific article

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent: Fig. 1

article

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage

scientific article

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

scientific article published on 2 November 2017

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation

scientific article published on 29 April 2016

Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?

scientific article published on 30 June 2020

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.

scientific article published on 06 July 2011

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

scientific article published on 08 October 2013

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

scientific article

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

scientific article

Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays

scientific article

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

scientific article published on 24 August 2010

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

scientific article published on 01 July 2009

Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts.

scientific article published on 03 December 2016

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

scientific article

Antibody response against the glomerular basement membrane protein agrin in patients with transplant glomerulopathy

scientific article published on 01 February 2005

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

scientific article published on 19 July 2013

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

scientific article published on 06 October 2015

Anticarbamylated protein antibodies can be detected in animal models of arthritis that require active involvement of the adaptive immune system

scientific article published on 04 February 2015

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts

scientific article

Arthritis autoantibodies in individuals without rheumatoid arthritis: follow-up data from a Dutch population-based cohort (Lifelines)

scientific article published on 28 June 2020

Association of anti-carbamylated protein antibodies with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

scientific article published on February 2015

Autoantibodies against complement components and functional consequences.

scientific article published on 20 June 2013

Autoantibodies against mannose-binding lectin in systemic lupus erythematosus

scientific article published on 01 November 2003

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

scientific article

Autoantibodies to complement components.

scientific article

Autoantibody testing to predict response to therapy in RA

article

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

scientific article published on 01 May 2012

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

scientific article published on 26 February 2018

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis.

scientific article published on 9 March 2017

Biomarkers for rheumatoid and psoriatic arthritis.

scientific article published on 28 April 2015

Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice

scientific article published on 26 August 2009

Breach of autoreactive B cell tolerance by post-translationally modified proteins

scientific article published on 25 April 2017

C-reactive protein in myocardial infarction binds to circulating microparticles but is not associated with complement activation

article

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

scientific article

C1q, antibodies and anti-C1q autoantibodies.

scientific article published on 29 May 2015

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes

scientific article published on 21 April 2017

C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack

scientific article published in Journal of Biological Chemistry

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

scientific article published on June 2005

C4b-binding protein in Alzheimer's disease: Binding to Aβ1–42 and to dead cells

scientific article published on 16 June 2008

C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.

scientific article

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

scientific article published on 28 October 2013

Carbamylation reduces the capacity of IgG for hexamerization and complement activation

scientific article published on 05 January 2020

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

scientific article published on 26 April 2013

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

article

Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis

scientific article published on June 2012

Complement Activation in Patients With Diabetic Nephropathy.

scientific article

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis

scientific article published on 23 October 2018

Complement activation and inhibition: a delicate balance.

scientific article published on 12 January 2009

Complement activation and regulation in rheumatic disease

scientific article published on 01 October 2019

Complement activation by (auto-) antibodies.

scientific article published on 14 July 2011

Complement activation in Glioblastoma multiforme pathophysiology: evidence from serum levels and presence of complement activation products in tumor tissue

scientific article published on 18 November 2014

Complement and renal disease.

scientific article

Complement component C1q as serum biomarker to detect active tuberculosis

scientific article published in 2018

Complement inhibitor C4b-binding protein in primary Sjögren's syndrome and its association with other disease markers

scientific article published in April 2009

Complement levels and anti-C1q autoantibodies in patients with neuropsychiatric systemic lupus erythematosus.

scientific article published in July 2016

Complement production and regulation by dendritic cells: molecular switches between tolerance and immunity

scientific article published on October 2008

Correction: C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack

scientific article published on 01 July 2020

Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.

scientific article published on 31 August 2008

Diagnostic and prognostic significance of anti-C1q antibodies in systemic lupus erythematosus.

scientific article published on November 2003

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

scientific article published on 31 May 2019

Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

scientific article published on 01 June 2002

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

scientific article published on 10 June 2011

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example.

scientific article published on 3 May 2018

Excretions/secretions from medicinal larvae (Lucilia sericata) inhibit complement activation by two mechanisms

scientific article published on 26 December 2016

Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients

scientific article published on 13 March 2020

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

scientific article published on 13 January 2015

Factor H Autoantibodies in Patients with Antiphospholipid Syndrome and Thrombosis

scientific article published on 15 August 2015

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

scientific article

Five decades of Dutch immunology

scientific article published on 18 October 2014

Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis.

scientific article published in July 2013

Genetic, molecular and functional analyses of complement factor I deficiency

scientific article

Glomerular C4d deposition can precede the development of focal segmental glomerulosclerosis

scientific article published on 16 May 2019

Glomerular deposition of C1q and anti-C1q antibodies in mice following injection of antimouse C1q antibodies

scientific article published on 01 April 2003

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

scientific article published in June 2010

HLA-B*08 identified as the most associated MHC locus for anti-carbamylated protein antibody-positive/anti-CCP-negative rheumatoid arthritis

scientific article published on 31 December 2020

Human neutrophil peptide-1 inhibits both the classical and the lectin pathway of complement activation

scientific article published on 19 April 2007

Identification of Lifelines participants at high risk for development of rheumatoid arthritis

article

Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections.

scientific article published on 18 October 2014

Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis

scientific article published on 10 March 2017

Immune deposition of C1q and anti-C1q antibodies in the kidney is dependent on the presence of glomerular IgG

scientific article published on 01 December 2003

In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission

scientific article published on 25 July 2018

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

scholarly article by Emma C de Moel et al published 18 January 2019 in Arthritis Research and Therapy

Infiltrating dendritic cells contribute to local synthesis of C1q in murine and human lupus nephritis

scientific article

Inverse correlation between serum complement component C1q levels and whole blood type-1 interferon signature in active tuberculosis and QuantiFERON-positive uveitis: implications for diagnosis

scientific article published on 16 October 2020

Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency

scientific article published on 19 October 2020

Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis.

scientific article published on 5 March 2013

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF.

scientific article published on 02 August 2016

Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency

scientific article

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

scientific article published on 01 September 2020

Maturation of dendritic cells abrogates C1q production in vivo and in vitro

scientific article published on 15 January 2004

Molecular and functional analysis of complement factor I mutations in atypical haemolytic uraemic syndrome patients

scholarly article by Sara C. Nilsson et al published October 2008 in Molecular Immunology

Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I

scientific article

New biomarkers in rheumatoid arthritis

scientific article published on November 1, 2012

Novel genetic association of theVTCN1region with rheumatoid arthritis

scientific article published on 09 February 2012

Pitfalls in the detection of citrullination and carbamylation

scientific article published in December 2017

Predictive factors of radiological progression after 2 years of remission-steered treatment in early arthritis patients: a post hoc analysis of the IMPROVED study

scientific article published on 15 February 2016

Presence of anticitrullinated protein antibodies in a large population-based cohort from the Netherlands.

scientific article published on 2 January 2017

Production of complement components by cells of the immune system.

scientific article

Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation

scientific article

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method

scientific article

Regulation of complement activation by C-reactive protein: Targeting of the inhibitory activity of C4b-binding protein

Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein

scientific article published on June 2006

Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1.

scientific article published on November 2005

Reply

scientific article published on 09 October 2016

Rheumatoid arthritis-associated autoantibodies in non-rheumatoid arthritis patients with mucosal inflammation: a case-control study.

scientific article published on 9 July 2015

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

scientific article published on 9 February 2016

Role of Anti-Carbamylated Protein Antibodies Compared to Anti-Citrullinated Protein Antibodies in Indigenous North Americans With Rheumatoid Arthritis, Their First-Degree Relatives, and Healthy Controls.

scientific article published on 4 March 2016

Role of anti-C1q autoantibodies in the pathogenesis of lupus nephritis

scientific article

Role of complement and complement regulators in the removal of apoptotic cells.

scientific article published on 24 October 2007

Role of complement in innate immunity and host defense.

scientific article published on 17 February 2011

Screening for two or three autoantibodies in persons at risk for RA: implications of current data for clinical practice

scientific article published on 01 May 2019

Secretory form of rheumatoid arthritis-associated autoantibodies in serum are mainly of the IgM isotype, suggesting a continuous reactivation of autoantibody responses at mucosal surfaces

scientific article published on 14 August 2018

Serum autoantibodies directed against transglutaminase-2 have a low avidity compared with alloantibodies against gliadin in coeliac disease.

scientific article

Short article: Absence of serological rheumatoid arthritis biomarkers in inflammatory bowel disease patients with arthropathies

scientific article published on 06 December 2016

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

scientific article published on December 2016

Specific inhibition of the classical complement pathway by C1q-binding peptides.

scientific article

Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al

scientific article published on 15 April 2020

Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis

scientific article published on 14 April 2020

TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey

scientific article

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

scientific article published on 13 October 2011

The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells

scientific article published on 19 April 2004

The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching

scientific article published on 01 September 2018

The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis: a study exploring replication and the added value to ACPA and rheumatoid factor

scientific article published on 26 April 2016

The complement system as a potential therapeutic target in rheumatic disease.

scientific article published on 10 August 2017

The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations

scientific article published on 13 March 2013

The extensive glycosylation of the ACPA variable domain observed for ACPA-IgG is absent from ACPA-IgM

scientific article published on 26 July 2017

The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells

scientific article published on 9 February 2007

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA.

scientific article published on 30 November 2011

The influence of ACPA status and characteristics on the course of RA.

scientific article published on 31 January 2012

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens

scientific article published on July 2011

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

scientific article published on 15 August 2017

The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)

scientific article published on 01 December 2011

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical.

scientific article

The production and secretion of complement component C1q by human mast cells

scientific article

The risk of individual autoantibodies, autoantibody combinations and levels for arthritis development in clinically suspect arthralgia.

scientific article

The role of complement activation in autoimmune liver disease

scientific article published on 28 March 2020

The role of complement in antineutrophil cytoplasmic antibody-associated vasculitis

scientific article published on 01 January 2019

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

scientific article published on 24 November 2015

The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics

scientific article published on 10 April 2011

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis

scientific article published on 16 September 2018

Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production

scientific article published on 20 March 2017

Which elements of the criteria for RA are stable over time?

scientific article published on 10 August 2010

[The role of the complement system in the defence against infections and new ways of assessing the activation routes]

scientific article published on 01 November 2004

List of works by Leendert A Trouw

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis

A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

A mutation in factor I that is strongly associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

A role for mannose-binding lectin dysfunction in generation of autoantibodies in systemic lupus erythematosus

Activation of the lectin pathway in murine lupus nephritis

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

Analysis of binding sites on complement factor I that are required for its activity

Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes.

Anti-C1q autoantibodies in murine lupus nephritis

Anti-C1q autoantibodies, novel tests, and clinical consequences

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent: Fig. 1

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation

Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts.

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

Antibody response against the glomerular basement membrane protein agrin in patients with transplant glomerulopathy

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

Anticarbamylated protein antibodies can be detected in animal models of arthritis that require active involvement of the adaptive immune system

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts

Arthritis autoantibodies in individuals without rheumatoid arthritis: follow-up data from a Dutch population-based cohort (Lifelines)

Association of anti-carbamylated protein antibodies with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

Autoantibodies against complement components and functional consequences.

Autoantibodies against mannose-binding lectin in systemic lupus erythematosus

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

Autoantibodies to complement components.

Autoantibody testing to predict response to therapy in RA

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis.

Biomarkers for rheumatoid and psoriatic arthritis.

Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice

Breach of autoreactive B cell tolerance by post-translationally modified proteins

C-reactive protein in myocardial infarction binds to circulating microparticles but is not associated with complement activation

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

C1q, antibodies and anti-C1q autoantibodies.

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes

C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

C4b-binding protein in Alzheimer's disease: Binding to Aβ1–42 and to dead cells

C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

Carbamylation reduces the capacity of IgG for hexamerization and complement activation

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis

Complement Activation in Patients With Diabetic Nephropathy.

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis

Complement activation and inhibition: a delicate balance.

Complement activation and regulation in rheumatic disease

Complement activation by (auto-) antibodies.

Complement activation in Glioblastoma multiforme pathophysiology: evidence from serum levels and presence of complement activation products in tumor tissue

Complement and renal disease.

Complement component C1q as serum biomarker to detect active tuberculosis

Complement inhibitor C4b-binding protein in primary Sjögren's syndrome and its association with other disease markers

Complement levels and anti-C1q autoantibodies in patients with neuropsychiatric systemic lupus erythematosus.

Complement production and regulation by dendritic cells: molecular switches between tolerance and immunity

Correction: C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack

Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.

Diagnostic and prognostic significance of anti-C1q antibodies in systemic lupus erythematosus.

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example.

Excretions/secretions from medicinal larvae (Lucilia sericata) inhibit complement activation by two mechanisms