List of works - Seung-Jae Lee

A detergent-insoluble membrane compartment contains A beta in vivo

scientific article published in June 1998

A novel mechanism of interaction between alpha-synuclein and biological membranes

scientific article published on 17 May 2006

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

scientific article published in August 2002

Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

scientific article published on 13 October 2015

Cell-to-Cell Transmission of α-Synuclein Aggregates ⬇️

scientific article published on January 1, 2012

Cell-to-cell transmission of non-prion protein aggregates.

scientific article published on 12 October 2010

Controlling the mass action of alpha-synuclein in Parkinson's disease

scientific article published on 02 September 2008

FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis

scientific article published on 2 September 2015

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.

scientific article published on 30 April 2015

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

scientific journal article

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

scientific article published on June 2005

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

scientific article published on 01 October 2020

Lack of direct role of parkin in the steady-state level and aggregation of alpha-synuclein and the clearance of pre-formed aggregates.

scientific article published on 28 November 2005

Neurodegeneration: Aggregates feel the strain.

scientific article published on 10 June 2015

Neurodevelopmental defects and neurodegenerative phenotypes in human brain organoids carrying Parkinson's disease-linked <i>DNAJC6</i> mutations

scientific article published on 17 February 2021

Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions

scientific article published on 24 March 2010

Novel covalent modifications of alpha-synuclein during the recovery from proteasomal dysfunction

scientific article published on 19 June 2006

The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity

scientific article

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.