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List of works by Inti Zlobec

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

A Digital Pathology-Based Shotgun-Proteomics Approach to Biomarker Discovery in Colorectal Cancer

scientific article published on 12 December 2019

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma

scientific article published on 04 April 2019

A next-generation tissue microarray (ngTMA) protocol for biomarker studies

scientific article published on 23 September 2014

ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics

scientific article published on 16 December 2019

ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy

scientific article

Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma

scientific article published on February 2015

Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas.

scientific article published on 31 January 2018

Assessing downgrading of locally advanced rectal cancer after chemo-radiotherapy

scientific article published on 23 March 2011

Assessment of Tumor Regression of Esophageal Adenocarcinomas After Neoadjuvant Chemotherapy

scientific article published on 01 November 2014

Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning

scientific article published on 16 December 2019

CD47 protein expression in acute myeloid leukemia: A tissue microarray-based analysis

scientific article published on 20 April 2015

CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia

scientific article published on 28 December 2016

CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival

scientific article

CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway

scientific article published on 26 September 2018

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer

scientific article published on 27 June 2019

Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing ⬇️

scientific article published on August 27, 2012

Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study

scientific article published in 2022

Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.

scientific article

Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma

scientific article published on 20 February 2019

Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung-A Single Center Analysis of 354 Cases

scientific article published on 04 September 2019

Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients.

scientific article published on 13 January 2017

Correction to: Assessment of individual tumor buds using keratin immunohistochemistry: moderate interobserver agreement suggests a role for machine learning

scientific article published on 03 January 2020

Correction: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells.

scientific article published on March 2017

Current opinion, status and future development of digital pathology in Switzerland

scientific article published on 19 December 2019

Cytokeratin-based assessment of tumour budding in colorectal cancer: analysis in stage II patients and prospective diagnostic experience

scientific article

DNA profiling of tumor buds in colorectal cancer indicates that they have the same mutation profile as the tumor from which they derive.

scientific article

Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+tumor infiltrating lymphocytes in ductal and lobular breast cancers ⬇️

scientific article published on April 3, 2012

Digital analysis and epigenetic regulation of the signature of rejection in colorectal cancer.

scientific article

Dose escalated intensity modulated radiotherapy in the treatment of cervical cancer.

scientific article published on 24 November 2015

Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer

scientific article published on 30 December 2015

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget

scientific article

Evaluation of Tumor Budding in Primary Colorectal Cancer and Corresponding Liver Metastases Based on H&E and Pancytokeratin Staining

scientific article published on 31 October 2019

Expression Patterns of TNFα, MAdCAM1 and STAT3 in Intestinal and Skin Manifestations of Inflammatory Bowel Disease

scientific article published on 22 November 2017

Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: comparison between primary tumors and metastases

scientific article published on 13 March 2017

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth.

scientific article published on 29 March 2018

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker

scientific article published on January 2014

High CD10 expression in lymph node metastases from surgically treated prostate cancer independently predicts early death ⬇️

scientific article published on 03 May 2011

High tumor budding stratifies breast cancer with metastatic properties

scientific article

High-level cytoplasmic cyclin D1 expression in lymph node metastases from prostate cancer independently predicts early biochemical failure and death in surgically treated patients ⬇️

scientific article published on March 25, 2011

Immunophenotypic profile of tumor buds in breast cancer.

scientific article published on 5 December 2017

Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts.

scientific article

Impact of the Microenvironment on Tumour Budding in Colorectal Cancer

scientific article published on 01 January 2018

Inflammatory response in serrated precursor lesions of the colon classified according to WHO entities, clinical parameters and phenotype-genotype correlation.

scientific article published on 25 February 2016

Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance

scientific article published on 16 April 2018

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

scientific article published in The Lancet

Intratumoral budding as a potential parameter of tumor progression in mismatch repair–proficient and mismatch repair–deficient colorectal cancer patients ⬇️

scientific article published on June 12, 2011

Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors

scientific article published on December 2009

Loss of E-cadherin independently predicts the lymph node status in colorectal cancer ⬇️

scientific article published on 01 February 2011

Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)

scientific article published on 14 December 2013

Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type

scientific article

MUC1 is upregulated in advanced prostate cancer and is an independent prognostic factor

scientific article

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer

scientific article published on 08 September 2020

Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer

scientific article published on 01 February 2008

Neuroendocrine Differentiation in Metastatic Conventional Prostate Cancer Is Significantly Increased in Lymph Node Metastases Compared to the Primary Tumors.

scientific article published on 28 July 2017

Novel biomarkers for the prediction of metastasis in colorectal cancer.

scientific article published on 14 December 2012

Oncologic long-term outcomes of emergency versus elective resection for colorectal cancer

scientific article published on 11 November 2019

PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential

scientific article

Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome

scientific article published on 9 November 2015

Potential clinical scenarios of tumour budding in colorectal cancer

scientific article published on 01 October 2019

Prediction of outcome in patients with low‐grade squamous intraepithelial lesions by fluorescence in situ hybridization analysis of human papillomavirus, TERC, and MYC ⬇️

scientific article published on February 13, 2013

Prognostic role of FGFR1 amplification in early-stage non-small cell lung cancer.

scientific article

Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer.

scientific article published on 2 February 2007

Proper paraffin slide storage is crucial for translational research projects involving immunohistochemistry stains

scientific article

Prospective Validation of Facial Nerve Monitoring to Prevent Nerve Damage During Robotic Drilling

scientific article published on 01 October 2019

Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. ⬇️

scientific article

Role of KCNMA1 in breast cancer

scientific article

Role of intra- and peritumoral budding in the interdisciplinary management of rectal cancer patients

scientific article published on 31 July 2012

Standardization of whole slide image morphologic assessment with definition of a new application: Digital slide dynamic morphometry ⬇️

scientific article published on October 29, 2011

Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.

scientific article

Stromal PD-1/PD-L1 Expression Predicts Outcome in Colon Cancer Patients

scientific article published on 21 September 2018

Synaptic proximity enables NMDAR signalling to promote brain metastasis

scientific article published on 18 September 2019

Systematic assessment of the prognostic impact of membranous CD44v6 protein expression in colorectal cancer

scientific article published on 01 November 2009

TREM-1 promotes intestinal tumorigenesis.

scientific article published in November 2017

TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

scientific article published on 12 September 2019

The ESRP1-GPR137 axis contributes to intestinal pathogenesis.

scientific article published on 4 October 2017

The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice

scientific article published on 26 June 2015

The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer

scientific article published on 05 June 2019

The apoptotic and proliferation rate of tumour budding cells in colorectal cancer outlines a heterogeneous population of cells with various impacts on clinical outcome

scientific article published on 28 December 2013

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer.

scientific article published on 3 August 2017

The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer

scientific article published on 16 July 2012

The predictive value of apoptosis protease-activating factor 1 in rectal tumors treated with preoperative, high-dose-rate brachytherapy

scientific article published on 01 January 2006

Tissue Microarray Technology for Molecular Applications: Investigation of Cross-Contamination between Tissue Samples Obtained from the Same Punching Device.

scientific article published on 2 April 2015

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours

scientific article

Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree?

scientific article published on 31 August 2018

Tumor border configuration added to TNM staging better stratifies stage II colorectal cancer patients into prognostic subgroups

scientific article published in September 2009

Tumor budding in colorectal cancer--ready for diagnostic practice?

scientific article published on 03 September 2015

Tumor budding in upper gastrointestinal carcinomas

scientific article published on 14 August 2014

Tumor budding predicts response to anti-EGFR therapies in metastatic colorectal cancer patients ⬇️

scientific article published on October 14, 2010

Tumour border configuration in colorectal cancer: proposal for an alternative scoring system based on the percentage of infiltrating margin

scientific article published on 4 February 2015

Tumour budding and CD8+ T-cells: "attackers" and "defenders" in rectal cancer with and without neoadjuvant chemoradiotherapy

scientific article published on 19 December 2020

Tumour budding in colorectal cancer: molecular rationale for clinical translation

scientific article published on 29 January 2018

Tumour budding in pancreatic cancer revisited: validation of the ITBCC scoring system

scientific article published on 17 April 2018

Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data

scientific article published on 02 November 2018

Tumour budding/T cell infiltrates in colorectal cancer: proposal of a novel combined score

scientific article published on 03 February 2020

VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer

scientific article published on 19 October 2015

VEGF as a predictive marker of rectal tumor response to preoperative radiotherapy

scientific article published on 01 December 2005

Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung-a single-center analysis of 354 cases

scientific article published on 03 December 2019

Validation of the International Tumor Budding Consensus Conference 2016 recommendations on tumor budding in stage I-IV colorectal cancer

scientific article published on 11 November 2018

Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer.

scientific article published on 3 August 2007

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