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List of works by Evelyne Ségal-Bendirdjian

A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation.

scientific article

A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).

scientific article

Activation of both protein kinase A (PKA) type I and PKA type II isozymes is required for retinoid-induced maturation of acute promyelocytic leukemia cells.

scientific article published on March 2013

Antitumor trans-N-heterocyclic carbene-amine-Pt(II) complexes: synthesis of dinuclear species and exploratory investigations of DNA binding and cytotoxicity mechanisms.

scientific article published on 20 February 2013

Complex context-relationships between DNA methylation and accessibility, histone marks, and hTERT gene expression in acute promyelocytic leukemia cells: perspectives for all-trans retinoic acid (ATRA) in cancer therapy

scientific article published on 01 April 2020

Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.

scientific article published on September 2004

Diagnostics, prognostic and therapeutic exploitation of telomeres and telomerase in leukemias

scientific article published on June 2006

Ectopic expression of Bcl-2 switches over nuclear signalling for cAMP-induced apoptosis to granulocytic differentiation

scientific article published on 01 November 2000

Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis

scientific article

Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells.

scientific article published on August 2016

Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT.

scientific article published on 9 May 2015

Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths

scientific article published on 13 June 2006

Inhibition of DNA topoisomerases I and II and induction of apoptosis by erbstatin and tyrphostin derivatives.

scientific article published on August 1994

Inhibition of human telomerase by oligonucleotide chimeras, composed of an antisense moiety and a chemically modified homo-oligonucleotide.

scientific article published on February 2005

Isolation and Characterization of Mitochondrial DNA-less Lines from Various Mammalian Cell Lines by Application of an Anticancer Drug, Ditercalinium ⬇️

scientific article published on October 9, 1997

Loss of the malignant phenotype of human neuroblastoma cells by a catalytically inactive dominant-negative hTERT mutant

scientific article published on 28 August 2012

Nuclear translocation of a leukocyte elastase Inhibitor/Elastase complex during staurosporine-induced apoptosis: role in the generation of nuclear L-DNase II activity

scientific article published on 01 January 2000

Platinum Complexes Can Bind to Telomeres by Coordination

scientific article published on 03 July 2018

Pro-survival role of p62 during granulocytic differentiation of acute myeloid leukemia cells

scientific article published on October 2014

Retinoic acid receptor alpha and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death.

scientific article published on December 2003

Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.

scientific article

Telomerase regulation in hematological cancers: a matter of stemness?

scientific article published on 07 February 2009

Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL.

scientific article published on April 2006

Telomeres and telomerase: Pharmacological targets for new anticancer strategies?

scientific article

Telomeres and telomerase: from basic research to clinical applications

scientific article published on 14 October 2007

The telomere story or the triumph of an open-minded research

scientific article published on 22 January 2010

WT1 expression is inversely correlated with MYCN amplification or expression and associated with poor survival in non-MYCN-amplified neuroblastoma

scientific article published on 15 October 2015

[Cell death signalling: recent advances and therapeutic application].

scientific article

[Current concepts on apoptotic signalling pathways: new targets for anticancer strategies].

scientific article

cAMP-Dependent Protein Kinase A (PKA)-Mediated c-Myc Degradation Is Dependent on the Relative Proportion of PKA-I and PKA-II Isozymes

scientific article

cFos mediates cAMP-dependent generation of ROS and rescue of maturation program in retinoid-resistant acute promyelocytic leukemia cell line NB4-LR1.

scientific article

hTERT promotes imatinib resistance in chronic myeloid leukemia cells: therapeutic implications

scientific article published on March 2011

p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.

scientific article

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