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List of works by Bernhard Ryffel

A New Bifidobacteria Expression SysTem (BEST) to Produce and Deliver Interleukin-10 in

scientific article published in 2018

A detrimental role for invariant natural killer T cells in the pathogenesis of experimental dengue virus infection

scientific article

A novel dendritic cell subset involved in tumor immunosurveillance

scientific article published on 29 January 2006

AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging

scientific article

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

scientific article

Activation of Invariant NKT Cells by Toll-like Receptor 9-Stimulated Dendritic Cells Requires Type I Interferon and Charged Glycosphingolipids

article

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

scientific article (publication date: October 2009)

Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannan

scientific article (publication date: 7 September 2007)

Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation

scientific article (publication date: 2012)

All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus ⬇️

scientific article published on September 13, 2011

Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs

scientific article published on 23 April 2009

Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors

scientific article

American Journal of Clinical and Experimental Immunology: Editorial Board (2012) e-Century Publishing Corporation

scientific article published on 30 May 2012

An Iron-Rich Diet Decreases the Mycobacterial Burden and Correlates With Hepcidin Upregulation, Lower Levels of Proinflammatory Mediators, and Increased T-Cell Recruitment in a Model of Mycobacterium bovis Bacille Calmette-Guerin Infection

scientific article published on 2 August 2017

Anisakis pegreffii-induced airway hyperresponsiveness is mediated by gamma interferon in the absence of interleukin-4 receptor alpha responsiveness

scientific article

Anti-CD3 antibody-induced expression of both p55 and p75 chains of the high affinity interleukin-2 receptor on human T lymphocytes is inhibited by cyclosporin A.

scientific article published in January 1990

Anti-Pseudomonas aeruginosa serotype O11 LPS immunoglobulin M monoclonal antibody panobacumab (KBPA101) confers protection in a murine model of acute lung infection

scientific article published on 24 February 2011

Antibody-independent thrombocytopenia in lactate dehydrogenase-elevating virus-infected mice

scientific article

Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis

scientific article

Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses

scientific article published on 14 July 2014

Arthropod-derived histamine-binding protein prevents murine allergic asthma

scientific article

Arthropod-derived protein EV131 inhibits histamine action and allergic asthma

scientific article

Bifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung Injury

scientific article

Binding of active cyclosporins to cyclophilin A and B, complex formation with calcineurin A.

scientific article

Biochemical and morphological characterization of vascular and lymphocytic interleukin-4 receptors

scientific article published on October 1996

Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice ⬇️

scientific article published on February 27, 2013

Blockade of IL-33R/ST2 Signaling Attenuates Ileitis Depending on IL-22 Expression

Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria

scientific article

Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin

scientific article published in November 2005

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

scientific article published on 09 May 2016

CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model

scientific article published on 23 August 2013

Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

scientific article published on July 2016

Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells

scientific article published on 16 March 2012

Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation

scientific article published on 24 February 2015

Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

scientific article published on 25 May 2020

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

scientific article published on 2 December 2012

Comparison of the pharmacological profiles of cyclosporine, (Nva2)-cyclosporine and (Val2)dihydro-cyclosporine.

scientific article published in June 1985

Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury

scientific article

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

scientific article

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Contribution of TNF/TNF receptor and of Fas ligand to toxicity in murine models of endotoxemia and bacterial peritonitis

scientific article published in January 1995

Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF.

scientific article

Correction of the TNF-LT alpha-deficient phenotype by bone marrow transplantation

scientific article published on January 1998

Correction or transfer of immunodeficiency due to TNF-LT alpha deletion by bone marrow transplantation

scientific article

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation

scientific article published on March 3, 1992

Critical role of IL-33 receptor ST2 in experimental cerebral malaria development

scientific article published on 20 March 2015

Crucial role of TNF receptors 1 and 2 in the control of polymicrobial sepsis

scientific article

Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice

scientific article

Cutting edge: Priming of NK cells by IL-18.

scientific article published on August 2008

Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria

scientific article published on 17 December 2010

Cyclosporin A enhances the calcium-dependent induction of AP-1 complex and c-fos mRNA in a T cell lymphoma

scientific article published on December 1996

Demonstration of ternary immunophilin-calcineurin complexes with the immunosuppressants cyclosporin and macrolide FK506.

scientific article published on April 1994

Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation

scientific article published on 05 August 2008

Dengue virus infection: current concepts in immune mechanisms and lessons from murine models

scientific article published on February 2014

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

scientific article published on 22 May 2011

Diagnostic accuracy of a selected signature gene set that discriminates active pulmonary tuberculosis and other pulmonary diseases

scientific article published on 20 September 2017

Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection

scientific article published on 10 October 2013

Differential role of all-trans retinoic acid in promoting the development of CD4+ and CD8+ regulatory T cells

scientific article published on 30 September 2013

Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling

scientific article published on May 1996

Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate

scientific article

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects

scientific article published in January 2005

Distribution of the cyclosporine binding protein cyclophilin in human tissues

scientific article published on March 1991

Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection

scientific article

Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis

scientific article

Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells

scientific article published on 26 May 2010

Dual Role of IL-22 in Allergic Airway Inflammation and its Cross-talk with IL-17A

article

Dual effects of p38 MAPK on TNF-dependent bronchoconstriction and TNF-independent neutrophil recruitment in lipopolysaccharide-induced acute respiratory distress syndrome

scientific article published in July 2005

Efficacy of membrane TNF mediated host resistance is dependent on mycobacterial virulence

scientific article published on 22 October 2007

Elucidation of toll-like receptor and adapter protein signaling in vascular dysfunction induced by gram-positive Staphylococcus aureus or gram-negative Escherichia coli.

scientific article

Endogenous leukemia inhibitory factor attenuates endotoxin response

scientific article

Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice

scientific article published in September 2002

Enhancement of Methacholine-Evoked Tracheal Contraction Induced by Bacterial Lipopolysaccharides Depends on Epithelium and Tumor Necrosis Factor ⬇️

scientific article published on March 11, 2012

Evidence for shared receptor proteins for human interleukin-3 and granulocyte-macrophage colony-stimulating factor in the human M-07 cell line

scientific article published on January 1993

Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells

scientific article

Experimental autoimmunity

scientific article

Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy

scientific article published on January 1986

Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis

scientific article published on 3 June 2010

Fatal Mycobacterium bovis BCG infection in TNF-LT-alpha-deficient mice

scientific article published in March 2000

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.

scientific article published on December 2004

Functional and morphological differences of the lung upon acute and chronic ozone exposure in mice.

scientific article published on 13 July 2018

GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands

scientific article

GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection.

scientific article

Gain of function mutation and inflammasome driven diseases in human and mouse models

scientific article published on 30 March 2018

Glufosinate aerogenic exposure induces glutamate and IL-1 receptor dependent lung inflammation

scientific article

Growth inhibition of human colorectal-carcinoma cells by interleukin-4 and expression of functional interleukin-4 receptors

scientific article published on November 1994

Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1.

scientific article published on May 1996

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

scientific article published on 2 November 2017

Hepatic steatosis in the absence of tumor necrosis factor in mice

scientific article published in December 2005

Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model

scientific article

Histamine plays an essential regulatory role in lung inflammation and protective immunity in the acute phase of Mycobacterium tuberculosis infection

scientific article published on 12 October 2009

Histamine scavenging attenuates endotoxin-induced acute lung injury

scientific article published in November 2005

Humoral Responses Elicited by Adenovirus Displaying Epitopes Are Induced Independently of the Infection Process and Shaped by the Toll-Like Receptor/MyD88 Pathway

scientific article published on 5 February 2018

Humoral immunity and CD4+ Th1 cells are both necessary for a fully protective immune response upon secondary infection with Brucella melitensis

scientific article

IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner

scientific article (publication date: December 2011)

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis

scientific article

IL-12Rβ2 is essential for the development of experimental cerebral malaria

scientific article published on 11 January 2012

IL-17 receptor signaling is required to control polymicrobial sepsis

scientific article

IL-17A Plays a Critical Role in the Pathogenesis of Liver Fibrosis through Hepatic Stellate Cell Activation ⬇️

scientific article published on July 10, 2013

IL-17A modulates oxidant stress-induced airway hyperresponsiveness but not emphysema

scientific article

IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis

scientific article published on 26 April 2010

IL-18 Induces PD-1-Dependent Immunosuppression in Cancer

IL-1R1-MyD88 axis elicits papain-induced lung inflammation.

scientific article published on 28 August 2016

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

scientific article published on December 2007

IL-1α induces CD11blow alveolar macrophage proliferation and maturation during granuloma formation

IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection

scientific article published on 17 April 2013

IL-23 promotes intestinal Th17 immunity and ameliorates obesity associated metabolic syndrome in a murine high-fat diet model

scientific article published on 2 May 2018

IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells

scientific article published on 6 February 2015

Identification of the Multidrug Resistance-Related Membrane Glycoprotein as an Acceptor for Cyclosporine ⬇️

scientific article published on January 1, 1991

Immunopathologic effects of tumor necrosis factor alpha in murine mycobacterial infection are dose dependent

scientific article published on December 2000

Immunosuppression and cancer: the ciclosporin case

scientific article published on January 1, 1992

In Situ Characterization of Splenic Brucella melitensis Reservoir Cells during the Chronic Phase of Infection in Susceptible Mice

scientific article published on 16 September 2015

In situ detection of cyclosporin A: evidence for nuclear localization of cyclosporine and cyclophilins.

scientific article published on November 1995

In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice

scientific article

In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria

scientific article

Induced CD4+ forkhead box protein-positive T cells inhibit mast cell function and established contact hypersensitivity through TGF-β1.

scientific article

Induced Foxp3+ regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases? ⬇️

scientific article published on November 22, 2011

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge

scientific article

Inflammasome, IL-1 and inflammation in ozone-induced lung injury

scientific article

Inflammasome-IL-1-Th17 response in allergic lung inflammation

scientific article published on 06 December 2011

Inhibition of interleukin 4 receptor expression on human lymphoid cells by cyclosporin

scientific article published in May 1990

Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection

scientific article published on 2 March 2016

Interferon gamma receptor deficient mice are resistant to endotoxic shock

scientific article

Interferon-gamma enhances tumor necrosis factor-alpha production by inhibiting early phase interleukin-10 transcription

scientific article published in December 1996

Interferon-gamma is essential for the development of cerebral malaria

scientific article published on April 1997

Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection

scientific article

Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice

scientific article

Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection

scientific article published in November 2008

Interleukin-17 is a negative regulator of established allergic asthma

scientific article

Interleukin-1α Mediates Ozone-Induced Myeloid Differentiation Factor-88-Dependent Epithelial Tissue Injury and Inflammation.

scientific article

Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages

scientific article published on 31 January 2012

Interleukin-33 contributes to disease severity in Dengue virus infection in mice

scholarly article by Rafael Elias Marques et al published December 2018 in Immunology

Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells

scientific article

Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin

scientific article

Interleukin-36γ induced by the TLR3-SLUG-VDR axis promotes wound healing via REG3A.

scientific article

Interleukin-4 (IL-4) and IL-13 bind to a shared heterodimeric complex on endothelial cells mediating vascular cell adhesion molecule-1 induction in the absence of the common gamma chain

scientific article published on May 1996

Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice

scientific article published in May 1994

Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production

scientific article

Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide

scientific article published on 21 June 2012

Limited Contribution of IL-36 versus IL-1 and TNF Pathways in Host Response to Mycobacterial Infection

scientific article published on 7 May 2015

Limited role for lymphotoxin α in the host immune response to Mycobacterium tuberculosis

scientific article published on 3 September 2010

Lipopolysaccharide-induced glomerulonephritis develops in the absence of interferon-gamma signaling.

scientific article

Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway

scientific article published on 26 November 2009

Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice

scientific article

Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate--the marmoset

scientific article

MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression

scientific article published on 03 August 2020

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

scientific article published on February 2013

Membrane TNF confers protection to acute mycobacterial infection

scientific article

Membrane tumor necrosis factor confers partial protection to Listeria infection

scientific article

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

scientific article

Molecular basis of carrageenan-induced cytokines production in macrophages

scientific article published on 07 September 2020

Mouse nidovirus LDV infection alleviates graft versus host disease and induces type I IFN-dependent inhibition of dendritic cells and allo-responsive T cells

scientific article

Muc5b-deficient mice develop early histological lung abnormalities

scientific article published on 07 November 2019

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice

scientific article

Murine cerebral malaria development is independent of toll-like receptor signaling

scientific article

MyD88 Signaling in B Cells Regulates the Production of Th1-dependent Antibodies to AAV ⬇️

scientific article published on May 29, 2012

MyD88 as a therapeutic target for inflammatory lung diseases

scientific article published on 16 April 2018

MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection

scientific article published on February 2013

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression

scientific article published on 26 June 2009

Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits Mycobacterium smegmatis-induced cytokine production by human macrophages in vitro

scientific article

Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro

scientific article published in January 2006

Mycobacterium tuberculosis infection of the 'non-classical immune cell'.

scientific article published on 24 March 2015

Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis

scientific article published on 23 February 2017

Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection

NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.

scientific article published on 8 July 2004

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

article

NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

scientific article published on 8 September 2017

Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum

scientific article

Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase.

scientific article published on May 1995

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice

scientific article

Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice

scientific article

Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation

scientific article

Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R.

scientific article published on 23 December 2016

New cyclosporine derivative SDZ IMM 125: in vitro and in vivo pharmacologic effects and toxicologic evaluation.

scientific article

Nitric oxide enhances Th9 cell differentiation and airway inflammation

scientific article

Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways.

scientific article

Novel bacterial delivery system with attenuated Salmonella typhimurium carrying plasmid encoding Mtb antigen 85A for mucosal immunization: establishment of proof of principle in TB mouse model.

scientific article

Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria

scientific article

Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands

scientific article

Oral artesunate prevents Plasmodium berghei Anka infection in mice

scientific article published on March 2003

Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway

scientific article published on 16 October 2017

Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice

scientific article published in June 2003

Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by Interleukin-33.

scientific article

PGE2 reduces nephrotoxicity and immunosuppression of cyclosporine in rats

scientific article published on January 1986

Parasite killing in murine malaria does not require nitric oxide production

scientific article published on February 1999

Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection

scientific article published on 19 May 2010

Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain

scientific article published on 01 March 2015

Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation

scientific article published on 20 December 2016

Pharmacokinetics of cyclosporine in toxicological studies

scientific article published in December 1986

Phenotypic and functional characteristic of a newly identified CD8+Foxp3−CD103+ regulatory T cells ⬇️

scientific article published on July 15, 2013

Polyclonal CD4+Foxp3+ Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome ⬇️

scientific article published on July 6, 2012

Prevention of intestinal allergy in mice by rflaA:Ova is associated with enforced antigen processing and TLR5-dependent IL-10 secretion by mDC

scientific article

Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells

scientific article (publication date: 2012)

Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection

scientific article published on 09 June 2008

Protein kinase C-theta is required for development of experimental cerebral malaria

scientific article

Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen

scientific article

Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome

scientific article

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

scientific article published in June 2009

Reactivation of latent tuberculosis by an inhibitor of inducible nitric oxide synthase in an aerosol murine model

scientific article published in November 2002

Reactivation of latent tuberculosis infection in TNF-deficient mice

scientific article published in September 2003

Reactivation of tuberculosis by tumor necrosis factor neutralization

scientific article published on 30 March 2007

Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection

scientific article

Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG.

scientific article published on 30 October 2013

Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response

scientific article published on January 1997

Rodent nutritional model of steatohepatitis: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency

scientific article published in January 2006

Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection

scientific article published on 12 December 2014

Role of interferon-gamma in contact hypersensitivity assessed in interferon-gamma receptor-deficient mice

scientific article published in September 1995

Role of interferon-gamma in interleukin 12-induced pathology in mice.

scientific article published on December 1995

Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension

scientific article published on 13 July 2016

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice

scientific article

Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection

scientific article published on January 2011

SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth

scientific article published on 25 April 2013

Selective NOD1 Agonists Cause Shock and Organ Injury/DysfunctionIn Vivo

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

scientific article published on 24 February 2014

Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain

scientific article published on 26 August 2015

Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of Th17 cells in the lymph nodes

scientific article published on 12 June 2018

TLR2-dependent mast cell activation contributes to the control of Mycobacterium tuberculosis infection

scientific article

TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa

scientific article

TLR9-dependent induction of intestinal alpha-defensins by Toxoplasma gondii

scientific article published on 19 May 2010

TNF in host resistance to tuberculosis infection

scientific article published on 18 February 2010

TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis

scientific article published on 26 June 2015

Targeting the NLRP3 inflammasome to reduce diet-induced metabolic abnormalities in mice

scientific article published on 23 November 2015

The Emerging Roles of STING in Bacterial Infections

scientific article published on 15 June 2017

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

article

The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles

scientific article

The alternative cap-binding complex is required for antiviral defense in vivo

scientific article published on 19 December 2019

The anti-Pseudomonas aeruginosa antibody Panobacumab is efficacious on acute pneumonia in neutropenic mice and has additive effects with meropenem

scientific article

The course of Plasmodium chabaudi chabaudi infections in interferon‐gamma receptor deficient mice ⬇️

scientific article published on August 1, 1997

The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.

scientific article published in May 2008

The development and function of follicular helper T cells in immune responses ⬇️

scientific article published on 04 June 2012

The development of murine cerebral malaria does not require nitric oxide production

scientific article published on February 1999

The dual role of LBP and CD14 in response to Gram-negative bacteria or Gram-negative compounds

scientific article published on January 2003

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

scientific article

The launch of the American Journal of Clinical and Experimental Immunology ⬇️

scientific article published on June 21, 2012

The microtubule regulator stathmin is an endogenous protein agonist for TLR3.

scientific article

The plant extract Isatis tinctoria L. extract (ITE) inhibits allergen-induced airway inflammation and hyperreactivity in mice

scientific article

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

scientific journal article

The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo

scientific article published on May 1995

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells

scientific article

Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France

scientific article published on 6 June 2016

Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation

scientific article published on 7 February 2013

Toll like receptor - potential drug targets in infectious disease

scientific article published on December 2008

Toll-Like Receptors and Control of Mycobacterial Infection in Mice

Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology

scholarly article by François Vanhoutte et al published November 2007 in Microbes and Infection

Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells

scientific article

Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans

scientific article published in April 2004

Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis

scientific article

Toll-like receptor 2 is essential for the sensing of oxidants during inflammation

scientific article

Toll-like receptor 2 is required for optimal control of Listeria monocytogenes infection

scientific article published on April 2004

Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection

scientific article

Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice

scientific article published in September 2002

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

scientific article (publication date: September 2007)

Toll-like receptor and tumour necrosis factor dependent endotoxin-induced acute lung injury

scientific journal article

Toll-like receptor pathways in the immune responses to mycobacteria

scientific article published in August 2004

Toll-like receptors and control of mycobacterial infection in mice

scientific article published on January 2006

Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions

scientific article

Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy

scholarly article by Husnu Uysal published in July 2018

Transmembrane TNF-α is sufficient for articular inflammation and hypernociception in a mouse model of gout

article

Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy

scientific article published on 25 August 2017

Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses

scientific article published in May 2008

Tumor Necrosis Factor and Its Receptors Are Crucial to Control Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection in a Murine Model

scientific article published on 22 July 2016

Tumor Necrosis Factor-Alpha Targeting Can Protect against Arthritis with Low Sensitization to Infection.

scientific article published on 14 November 2017

Tumor necrosis factor alpha-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient mice

scientific article

Tumor necrosis factor is critical to control tuberculosis infection

scientific article published on 21 February 2007

Tumor necrosis factor is not associated with intestinal ischemia/reperfusion-induced lung inflammation

scientific article published in September 2010

Type I Interferon Signaling Contributes to Chronic Inflammation in a Murine Model of Silicosis

article

Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA.

scientific article published on 19 July 2013

Uncoupling between inflammatory and fibrotic responses to silica: evidence from MyD88 knockout mice

scientific article

Unravelling the roles of innate lymphoid cells in cerebral malaria pathogenesis

scientific article published on 8 November 2017

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

scientific article published on 12 February 2009

Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18.

scientific article published on 4 November 2011

VEGF kinoid vaccine, a therapeutic approach against tumor angiogenesis and metastases

scholarly article

iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice

scientific article

microRNA cluster 106a~363 is involved in T helper 17 cell differentiation

scientific article published on 15 June 2017

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